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Mental Disorders clinical trials

View clinical trials related to Mental Disorders.

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NCT ID: NCT03736057 Completed - Dementia Clinical Trials

Genetic Evaluation for Medication Selection (GEMS) Study

Start date: May 13, 2016
Study type: Observational

Investigators propose to determine whether knowing details about how a person's genes affect the way medicines work in the brain and body will help doctors pick more effective or safer medicine for that person. Target symptoms are restlessness, agitation, depression and related problems common in people with memory loss and dementia.

NCT ID: NCT03730974 Not yet recruiting - Clinical trials for Insomnia Due to Mental Disorder

Ball Blankets on Insomnia in Depression in Outpatient Clinics

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

The objective of the study is to examine the efficacy of Protac Ball BlanketsTM (PBB) and specifically if the PBB will extend the total sleep time of patients with insomnia due to depression in two psychiatric outpatient clinics at Aarhus University Hospital and Odense University Hospital. Furthermore, it will be examined whether the PBB will reduce the sleep onset latency, number of awakenings, need for sedatives and hypnotics, the self reported symptoms of depression and anxiety and improve the quality of sleep. 45 with depression and insomnia who receive outpatient treatment will be included in this study. The study is a randomized cross-over study. The data collection period lasts four weeks. Data will be collected using actigraphs, sleep diaries and questionnaires.

NCT ID: NCT03730831 Recruiting - Schizophrenia Clinical Trials

Narrative Exposure Therapy in Patients With Psychotic Disorders and a Posttraumatic Stress Disorder

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Adverse childhood experiences in psychotic disorders are associated with increased cognitive deficits, severe psychotic symptoms, and increased comorbidity. The number of different stress experiences also increases the probability of trauma-associated symptoms. Furthermore, neurobiological changes play a key role in the vulnerability of individuals with early traumas for mental and physical illnesses, among others for diseases of the schizophrenic spectrum disorder and the further course of the disease. The current project pursues a detailed recording of the course of symptoms in inpatients with psychosis to link this data with a systematic recording of childhood experiences and traumatic experiences and biological data. On a subsample of inpatients with psychosis and a comorbid post-traumatic stress disorder (PTSD), the researchers want to investigate whether symptom traits of existing psychotic disorders, biomolecular parameters and cognitive functions can be influenced by a trauma-specific treatment (NET), that has been proven to be effective in the treatment of PTSD.

NCT ID: NCT03729050 Recruiting - Rehabilitation Clinical Trials

Rehabilitation Coordinators in Specialist Psychiatry

Start date: October 24, 2018
Phase: N/A
Study type: Interventional

REKO-A is a randomized controlled intervention study that addressed women and men on sick leave in Uppsala County. Participants which are on sick leave due to mental illness.

NCT ID: NCT03724448 Recruiting - Clinical trials for Diagnosis, Psychiatric

The Efficacy of a Herbal Supplement in the Prevention of PTSD

Start date: May 1, 2018
Phase: Phase 1
Study type: Interventional

Psycho-traumatic disorders are a disabling condition whose epidemiological data vary according to the country but also the populations studied and the measuring instruments used. The estimated prevalence of posttraumatic stress disorder (PTSD) appeared to be increasing in recent years, and this appears to be due, among other things, to the improvement of the standardized evaluation procedure. The survey "Mental Health in General Population", conducted in metropolitan France between 1999 and 2003 on more than 36,000 people estimated its instantaneous prevalence (last month) of a full PTSD was 0.7% in the SMPG overall sample, with almost equal frequency between men (45%) and women (55%). This figure is close to that reported in a European population for the ESEMeD study. A very significant psychiatric comorbidity was found in subjects with PTSD, particularly with mood disorders, other anxiety disorders and addictive behaviors. The link with the suicidal risk was clearly established, which is the gravity of this pathology. The most important publications are made by American teams who have identified and evaluated the treatment of this pathology among veterans of the various wars led by the country.

NCT ID: NCT03721224 Recruiting - Psychogenic Cough Clinical Trials

Psychiatric Disorders in Children With Psychogenic Cough

Start date: September 1, 2018
Study type: Observational

The study aims to evaluate psychiatric disorders and clinical features of children with psychogenic cough. Psychiatric disorders are assessed via a semi-structured interview (Kiddie Schedule for Affective Disorders and Schizophrenia) and clinical features are investigated via sociodemographic form, which was developped by researchers. Investigator planned to compare psychiatric diagnoses, specifically anxiety and depression, with children referred to pediatric clinics.

NCT ID: NCT03715608 Completed - Clinical trials for Osteoarthritis, Knee

Total Knee Arthroplasty Combined With Psychological Intervention for Patients With Psychological Disorders

Start date: May 4, 2016
Phase: N/A
Study type: Interventional

Objective To evaluate the incidence of psychological problems in total knee arthroplasty (TKA) patients and examine whether perioperative psychological intervention can improve the outcomes of and patient satisfaction with TKA. Methods The investigators will prospectively collect clinical data from 400 patients who underwent primary TKA by the same surgeon at Peking University Third Hospital. The patients will be divided into 3 groups based on psychological status and intervention: the normal group comprised patients with a normal psychological status, while patients with an abnormal psychological status will be randomly divided into the intervention group, which received psychological interventions, and the control group, which do not receive any psychological interventions. The HSS(Hospital of special surgery) and WOMAC scores will be evaluated preoperatively, 3 months postoperatively and 6 months postoperatively. A self-administered satisfaction scale (very satisfied, somewhat satisfied, somewhat dissatisfied, very dissatisfied) that assessed overall satisfaction as well as satisfaction with pain relief and the ability to perform daily and leisure activities will be administered 6 months postoperatively. Hypothesis A certain percentage of TKA patients have preoperative psychological abnormalities. Preoperative psychological abnormalities can have an adverse effect on postoperative improvement in joint function and can reduce patient satisfaction. Preoperative psychological intervention can improve the prognosis of TKA patients with psychological disorders.

NCT ID: NCT03714893 Not yet recruiting - Clinical trials for Psychiatric Disorders Mood

The Analysis of Physical, Physiological and Behavioral Data Collected From Sensors That Track the Mental Condition of Psychiatric Patients

Start date: October 2018
Study type: Observational

An observational study that uses a digital system to collect physiological, physical and behavioral data using worn sensors on psychiatric patients suffering from schizophrenia, bipolar and schizoaffective disorders. The system will enable to analyze the data using a personal digital algorithm in order to detect changes in mental condition and or changes in adherence to medication treatment, and assist in identification of illegal drug usage.

NCT ID: NCT03713398 Not yet recruiting - Mental Disorder Clinical Trials

Mental Health Services for Prisoners With SMI

Start date: November 2018
Phase: N/A
Study type: Interventional

Interventions that address criminogenic risk factors, such as Thinking for a Change (T4C), are not used with prisoners with serious mental illness (SMI) because of the neurocognitive and social impairments associated with SMI. This study examines the effectiveness of T4C with a modified delivery system designed specifically to address the unique needs of persons with SMI in prison, including improving impulsivity, criminal attitudes, and interpersonal problem solving (treatment targets) and levels of aggression, and the amount of behavioral infractions and time spent in administrative segregation in prison (outcomes).

NCT ID: NCT03708341 Not yet recruiting - Sleep Deprivation Clinical Trials

Exogenous Melatonin in Intensive Care Unit Chronodisruption

Start date: November 15, 2018
Phase: Phase 3
Study type: Interventional

To this day, a small number of studies have evaluated the effect of melatonin on the modifications of the characteristics of sleep in critical care units, with mostly a small studied population. However, no study has been realized on a large population, nor has it evaluated the association between genetic factors and response to treatment (melatonin), hence the originality of our study. In our study we hypothesized that systematic melatonin usage in ICU can ameliorate the total sleep time and the fragmentation index and can decrease the confusion related to sleep deprivation.