Randomized Controlled Trial Clinical Trial
Official title:
A Series of N-of-1 Trials of Comparing Ginkgo Biloba Pills and Placebo in the Treatment of Coronary Heart Disease With Impaired Glucose Regulation
Background
Coronary heart disease has become a serious challenge to China with its high prevalence and
mortality. The impaired glucose regulation is prevalent in patients with cardiovascular
disease. However, there are few drugs that interfere early with impaired glucose regulation.
Ginkgo biloba extract is not only a commonly used drug for cardiovascular diseases, but also
has a significant effect in reducing blood sugar. Therefore, this study used a single case
randomized controlled trial to explore the efficacy of Ginkgo biloba pills in the treatment
of coronary heart disease patients with impaired glucose regulation.
Methods
This is a randomized, double-blind, placebo-controlled, three-period crossover trial for a
single subject.A total of 12 subjects will be recruited in this trial. The trial is divided
into three cycles, one cycle has two treatment periods. Ginkgo biloba pills and placebo will
be randomized during the treatment period. The test period will be lasted 58 weeks and
subjects will take 48 weeks. Subjects will be selected by the researcher strictly in
accordance with the inclusion and exclusion criteria.
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