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NCT06186713 Clinical Trial

Pulmonary Hypertension on Prognosis of Acute Myocardial Infarction Patients With Reduced Left Ventricular Function

Pulmonary Hypertension Clinical Trial

— STIMULATE  

Official title:
Pulmonary Hypertension on Prognosis of Acute Myocardial Infarction Patients With Reduced Left Ventricular Function (STIMULATE): A Single-center, Retrospective Cohort Study

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT06186713
Other study ID # XJTU1AF2023LSK-406
Secondary ID
Status Completed
Phase
First received
Last updated
Start date March 30, 2023
Est. completion date August 1, 2023

Study information
Verified date December 2023
Source First Affiliated Hospital Xi'an Jiaotong University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Pulmonary hypertension (PH) has a negative effect on acute myocardial infarction (AMI) patients and appears to be closely associated with reduced left ventricular function. However, its impact on AMI patients with reduced left ventricular function remains unclear. This retrospective study included AMI patients with reduced left ventricular function to investigate the prognostic value of PH in this specific type of patient. Meanwhile, a nomogram would be established basing on the identified independent risk factors, hoping to provide a novel risk stratification for them.

Recruitment information / eligibility
Status Completed
Enrollment 4784
Est. completion date August 1, 2023
Est. primary completion date July 31, 2023
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - The patients who were hospitalized for AMI with reduced left ventricular function at the First Affiliated Hospital of Jiaotong University from January 2018 to January 2022. Exclusion Criteria: - Myocardial infarction complicated by cardiac rupture. - Significant pre-existing heart failure. - Other comorbidities such as malignancy that may significantly affect prognosis. - Incomplete clinical data.

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• This was an observational study, and no Intervention was given to the patients.
This was an observational study, and no Intervention was given to the patients.

Locations
Country Name City State
China First Affiliated Hospital of Xian Jiaotong University Xi'an Shaanxi

Sponsors (1)
Lead Sponsor Collaborator
First Affiliated Hospital Xi'an Jiaotong University

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary The incidence of all-cause death All-cause death will be determined by clinical records or phone calls with patients and their family. 1-year after the AMI.
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