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Pregnancy Related clinical trials

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NCT ID: NCT04838340 Completed - Pregnancy Related Clinical Trials

Effect of Hypnobirthing Training on Fear, Pain, Satisfaction and, Birth Outcomes

Start date: May 4, 2019
Phase: N/A
Study type: Interventional

Background and Purpose: Hypnobirthing is childbirth education model. This model aims for women to have a painless, calm and more comfortable birth. In this study is aimed to determine the effect of Hypnobirthing training on fear of childbirth, birth pain, birth satisfaction and birth outcomes. Materials and Methods: This randomized controlled experimental study was performed in Maternity Hospital (Bursa, Turkey) . The minimum required sample size to be included in the study will calculated with G* power. The simple randomization method was use in the assignment of healthy and nulliparous pregnant women at 28-32 weeks of gestation to the groups. The assignment of the participants to the experimental group or control group was carried out with a computer-aided program. The nulliparous women was divided into two groups as the control group contained women who received the hospital's usual care, and the experimental group contained women who received the hypnobirthing training intervention. The fear of birth was measured with the Wijma Birth Expectancy/Experience Scale A and B (W-DEQ); labor pain was measured with Visual Analogue Scale (VAS); birth satisfaction was measured with Short Form of Birth Satisfaction Scale (BSS-R); birth outcomes will measure with postpartum Information form. The Statistical Package for the Social Sciences program (version 25.00) was use in data analysis.

NCT ID: NCT04838210 Enrolling by invitation - Pregnancy Related Clinical Trials

Elevating Voices, Addressing Depression, Toxic Stress and Equity in Group Prenatal Care

EleVATE GC
Start date: May 21, 2021
Phase: N/A
Study type: Interventional

This study will provide high-quality, representative data on the capacity of Elevating Voices, Addressing Depression, Toxic Stress and Equity in Group Prenatal Care (EleVATE GC) to reduce perinatal depression, preterm birth, and low birthweight in African-American women. If findings from this study indicate that EleVATE GC is feasible and effective, this model could be implemented nationwide to help achieve mental and obstetric health parity for low-income women of color in the United States.

NCT ID: NCT04830241 Active, not recruiting - Pregnancy Related Clinical Trials

Neonatal Hypotonia Associated With in Utero Exposure to Antidepressant

Start date: March 25, 2021
Phase:
Study type: Observational

To better characterize the neonatal hypotonia associated with in utero exposure to antidepressants, so far limited to clinical cases, we will perform an observational retrospective pharmacovigilance study, using two databases. First, disproportionality analysis in Vigibase®, the World Health Organization global database, will be perform between antidepressant drugs and neonatal hypotonia . Second, narratives from the French National Pharmacovigilance Database will be extracted.

NCT ID: NCT04828382 Recruiting - Cystic Fibrosis Clinical Trials

Prospective Study of Pregnancy in Women With Cystic Fibrosis

MAYFLOWERS
Start date: September 30, 2021
Phase:
Study type: Observational

In this study, the investigators aim to evaluate changes in lung function in women with cystic fibrosis (CF) during pregnancy and for 2 years after pregnancy based on exposure to highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators.

NCT ID: NCT04828070 Active, not recruiting - Pregnancy Related Clinical Trials

The Heart Outcomes in Pregnancy Expectations (H.O.P.E) Registry

Start date: December 1, 2020
Phase:
Study type: Observational [Patient Registry]

Prospective US registry of pregnant women with cardiac disease to address the substantial gaps in knowledge surrounding these patients, in order to improve future care.

NCT ID: NCT04825782 Recruiting - Pregnancy Related Clinical Trials

MiMBa Pregnancy Registry

Start date: February 22, 2021
Phase:
Study type: Observational

The MiMBa (Malaria in Mothers and Babies) Pregnancy Registry aims to generate robust evidence on the safety of a range of antimalarials when used in pregnancy, particularly in the first trimester. This will be a multi-country observational study and will be deployed in several field sites in Africa.

NCT ID: NCT04815044 Enrolling by invitation - Pregnancy Related Clinical Trials

Experiences From Pregnancy and Post-partum Period in Women With a History of Eating Disorders.

PREG_PED-t
Start date: December 1, 2020
Phase:
Study type: Observational

Women with the eating disorder bulimia nervosa (BN) have been found to have a higher risk of unplanned pregnancies than healthy women, and experience greater miscarriage, premature birth, birth complications, and postpartum depression. Other studies have found that women with eating disorders seem to find motivation to refrain from the eating disordered behavior for the sake of the fetus, but that it is highly different whether this gives sustained or only a temporary remission. Eating disorders are rarely detected in the primary health care service, nor during pregnancy or during follow-up in fertility clinics. Meeting a health care provider in the pregnancy care service who does not know about the eating disorder or who does not understand the disease well enough, can also make the management and experience of pregnancy and weight gain extra difficult. The aim of this study is to increase the knowledge on how women with a history of eating disorder experience their bodily changes, and how they experience the health service in pregnancy care and post-partum period.

NCT ID: NCT04814628 Recruiting - Anesthesia Clinical Trials

Assessment of Transnasal Humidified Rapid-insufflation Ventilatory Exchange (THRIVE) for Maternal Pre-oxygenation

PREOXCE
Start date: February 15, 2024
Phase: N/A
Study type: Interventional

The main objective of this study is to determine if the use of transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) can reduce by 90 seconds the time between the entry into the operating room of the volunteer and the moment when the anaesthetic drugs are ready and when the Oxygen Reserve Index has reached a plateau value for more than 10 seconds, a moment which would therefore allow the induction of general anaesthesia, compared to the pre-oxygenation with the face mask applied by the anaesthetist alone in charge of anaesthesia.

NCT ID: NCT04808973 Completed - HIV Infections Clinical Trials

DTG Plus 3TC for Prophylaxis of Mother-to-child Transmission of HIV Infection in Pregnant Women

PREGNANCY
Start date: July 1, 2021
Phase: Phase 3
Study type: Interventional

The study aims to evaluate the safety and efficacy of a 2 drugs ART regimen (lamivudine plus dolutegravir) for prevention of mother to child transmission in pregnant women with HIV. 20 pregnant women will be enrolled in this proof of concept protocol. They will be prescribed DTG-3TC (fixed-dose combination), and will be followed up to the end of gestation. Initially, a total of 10 pregnant women will be recruited for the first phase of the study. Once the first phase is successfully completed, 10 additional participants will be included in a second step.

NCT ID: NCT04805073 Recruiting - Pregnancy Related Clinical Trials

Treatment of Pruritus With Intramuscular Promethazine

Start date: August 9, 2021
Phase: Phase 4
Study type: Interventional

Neuraxial narcotics are commonly used in obstetric patients for cesarean delivery to help with pain control over the first 24 hours after the surgery. The aim is to evaluate effectiveness of promethazine (IMP) treatment of intrathecal morphine induced pruritus (ITIMIP). A treatment for ITMIP, other than naloxone, will allow for increased use of intrathecal narcotics and decrease the use of systemic opioids in the initial post-operative period.