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Pregnancy Related clinical trials

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NCT ID: NCT06127277 Enrolling by invitation - Pregnancy Related Clinical Trials

Next4You: A Fully Mobile Relationships Based Program for Youth in Foster Care

Start date: September 25, 2023
Phase: N/A
Study type: Interventional

The purpose of the study is to rigorously evaluate Next4You, an innovative, fully mobile program featuring 6 content modules, each containing 8-10 microlessons intended to reduce rates of unintended pregnancy and sexually transmitted infections (STI) and increase essential knowledge, attitudes, and skills among young people aged 16-19 currently in the foster care system in California.

NCT ID: NCT06002165 Enrolling by invitation - Hypertension Clinical Trials

Testing Implementation Strategies to Support Clinic Fidelity to an Outpatient Hypertension Bundle

ACHIEVE
Start date: October 4, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test an approach to improve care for pregnant and post-partum patients with high blood pressure. The study participants are providers and staff in prenatal care clinics, and the condition of interest is severe hypertension. The research questions are: 1. Does the ACHIEVE intervention increase the quality and accuracy of measuring patient blood pressure? 2. Does the ACHIEVE intervention increase the documentation of delivery of patient education on hypertension? 3. Does the ACHIEVE intervention result in better recognition and treatment of severe hypertension during practice sessions (simulations)? 4. Does the ACHIEVE intervention result in better recognition and treatment of severe hypertension for patients who come to the clinic? Participants from 20 clinics in North Carolina will work with an ACHIEVE Nurse Coordinator who will deliver training, coaching, and simulations. Three groups of clinics will be phased into Active Implementation every six months. The study team will examine data collected before, during, and after the intervention to see if the results show improvement.

NCT ID: NCT05889806 Enrolling by invitation - Clinical trials for Cardiovascular Diseases

AUD Biomarkers Study (Proteomic and Genomic Analysis of Biospecimens)

Start date: May 10, 2023
Phase:
Study type: Observational

Study purpose: to explore the entire spectrum of proteomic and genomic changes (amongst others) involved in diseases and in healthy/control populations. The Study is designed to discover biomarkers, develop and validate diagnostic assays, instruments and therapeutics as well as other medical research. Specifically, researchers may analyze proteins, RNA, DNA copy number changes, including large and small (1,000-100,000 kb) scale rearrangements, transcription profiles, epigenetic modifications, sequence variation, and sequence in both diseased tissue and case-matched germline DNA from Subjects.

NCT ID: NCT05867836 Enrolling by invitation - Pregnancy Related Clinical Trials

Multiple Micronutrient Supplementation vs Iron and Folic Acid Among Pregnant Women in Cambodia

MMS-Cambodia
Start date: March 1, 2023
Phase: N/A
Study type: Interventional

Iron and folic acid (IFA) supplements are currently provided to Cambodian women during pregnancy. However, recent research has showed benefit of a multiple micronutrient supplement (MMS) over just IFA alone on several outcomes of perinatal and infant health. The Ministry of Health in Cambodia has proposed a transition from IFA to MMS but would like to collect some formative research on this first to assess acceptability and adherence to MMS (over IFA) and help guide key messaging, packaging, and practices to guide the transition in Cambodia.

NCT ID: NCT05804838 Enrolling by invitation - Depression Clinical Trials

Investigation of the Effect of Mindfulness-Based Stress Reduction Program on in Pregnant Women

Start date: June 6, 2023
Phase: N/A
Study type: Interventional

This study was planned to examine the effects of the Mindfulness-Based Stress Reduction Program, which is one of the popular concepts of the 21st century, on depression, psychological well-being and prenatal attachment, which are likely to occur as a result of increased stress during an important period that requires adjustment as a result of physical, mental and cognitive changes during pregnancy. It will be conducted in a randomized parallel controlled experimental design type using Consolidated Standards of Reporting Trials (CONSORT) guidelines. It is planned to be carried out with the ZOOM Cloud Meetings program, which is an online education platform, with pregnant women who apply to the Health Sciences University Ümraniye Training and Research Hospital pregnancy polyclinic in the Ümraniye district of Istanbul. The universe of the research will be the pregnant women who applied to the Health Sciences University Ümraniye Training and Research Hospital pregnant outpatient clinic. Primiparous pregnant women who meet the inclusion criteria and willingly agree to participate in the study will be included in the study. 54 people in the intervention group, 54 people in the control group, and a total of 108 people will be taken. While the Conscious Awareness-Based Stress Reduction Program adapted for pregnant women will be applied to the intervention group, routine follow-up will be applied to the control group within the scope of the outpatient clinic follow-up of the relevant institution. Informed Voluntary Consent Form, Descriptive Characteristics Information Form, Psychological Well-Being Scale, Beck Depression Scale, Prenatal Attachment Scale and Conscious Awareness Scale will be administered to the participants included in the study. As a result of the findings, the discussion and results of the study will be written.

NCT ID: NCT05570630 Enrolling by invitation - COVID-19 Clinical Trials

VAX-MOM COVID-19: Increasing Maternal COVID-19 Vaccination

Start date: October 21, 2022
Phase: N/A
Study type: Interventional

COVID-19 infection during pregnancy is associated with increased risk of pre-eclampsia, preterm birth and stillbirth. Pregnant people with COVID-19 have a higher rate of ICU admission and intubation than those who are not pregnant. COVID-19 vaccine is recommended before pregnancy and during pregnancy to decrease these risks. Despite the benefits of COVID-19 vaccination, only 71% of pregnant women were vaccinated for COVID-19 as of June 2022 (most prior to pregnancy), with a much lower rate of 58% among non-Hispanic Black women. An effective intervention is needed to improve COVID vaccination rates for pregnant people overall. In this study, the investigators will perform a randomized controlled trial aimed at practice change in obstetricians' offices, with an overall goal of increasing maternal COVID-19 vaccination rates.

NCT ID: NCT05530863 Enrolling by invitation - Pregnancy Related Clinical Trials

Behavioral Relaxation Approaches for Insomnia in Pregnant Patients

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

This study will evaluate the effect of a simplified behavioral relaxation intervention to improve insomnia in pregnant women

NCT ID: NCT05385042 Enrolling by invitation - Pregnancy Related Clinical Trials

Iron and Immune Response to Vaccine (IRONMUM)

IRONMUM
Start date: June 18, 2022
Phase: Phase 4
Study type: Interventional

Iron deficiency causes anaemia and is common in pregnant women especially for those living in tropical regions where a high burden of infection and poor nutrition can compromise health. Low iron has been recognized as a cause of poor immune response because the group of cells that need to increase to make the immune response need iron to function. Vaccination is an important part of care during pregnancy because components of the immune response can cross the placenta and protect the young infant. More recently COVID-19 vaccination has also been recommended for pregnant women due to their higher risk of dying from this infection. Deeper investigation of whether low iron results in poor immune response is needed because the vaccines may not be providing as much protection as needed. The World Health Organization also recommends nutritional iron supplements in pregnancy and whether these improve immune response to vaccines is also not known. This study aims to test the body's immune response to recommended vaccines in pregnant women (tetanus and diphtheria (combination) and COVID-19 vaccine (if indicated)) who are anaemic and receiving iron supplements and compare their response to women who are not anaemic, who only receive a preventive, lower dose of supplement.

NCT ID: NCT05033366 Enrolling by invitation - Pregnancy Related Clinical Trials

Relationship Between Fertility Hormone Patterns and Pregnancy Rates.

Start date: March 1, 2020
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to determine if certain patterns of hormone levels during the menstrual cycle are correlated with different pregnancy outcomes.

NCT ID: NCT04838210 Enrolling by invitation - Pregnancy Related Clinical Trials

Elevating Voices, Addressing Depression, Toxic Stress and Equity in Group Prenatal Care

EleVATE GC
Start date: May 21, 2021
Phase: N/A
Study type: Interventional

This study will provide high-quality, representative data on the capacity of Elevating Voices, Addressing Depression, Toxic Stress and Equity in Group Prenatal Care (EleVATE GC) to reduce perinatal depression, preterm birth, and low birthweight in African-American women. If findings from this study indicate that EleVATE GC is feasible and effective, this model could be implemented nationwide to help achieve mental and obstetric health parity for low-income women of color in the United States.