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Pregnancy Related clinical trials

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NCT ID: NCT05285956 Terminated - Pregnancy Related Clinical Trials

Feasibility of Calm to Reduce Stress and Improve Sleep During Pregnancy

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Purpose: Test the effects of using Calm for its impact on stress, anxiety, and sleep in pregnant women using the following aims: Aim #1: Determine the feasibility of using Calm. Aim #2: Determine the preliminary efficacy of using Calm on stress, anxiety, and sleep. Exploratory Aim #3: Explore the preliminary efficacy of using Calm on self-reported birth outcomes

NCT ID: NCT05175040 Terminated - Pregnancy Related Clinical Trials

PROphylactic Manual RotatIon in the Second stagE of Labor

PROMISE
Start date: March 4, 2022
Phase: N/A
Study type: Interventional

This is a randomized controlled trial to determine whether prophylactic manual rotation for fetuses identified to have persistent occiput posterior or occiput transverse presentation (POP/OTP) at the initiation of the second stage of labor in nulliparous individuals reduces rates of operative delivery, second stage of labor duration, and resultant adverse clinical outcomes compared to standard management of the second stage of labor.

NCT ID: NCT04983667 Terminated - Clinical trials for Autism Spectrum Disorder

Zinc-AA Supplementation During Pregnancy & Lactation to Assess Effects on ASD Prevalence in Offspring

Start date: May 27, 2021
Phase: N/A
Study type: Interventional

Autism and associated entities, grouped under the Autism Spectrum Disorders (ASD) is the fastest growing intellectual disability in the world, statistics signal for a 1 to 3% prevalence on infants. The cause is unknown, although some data suggest that zinc deficiency during pregnancy may have an important role in its presentation. This study seeks to supplement the nutrition of randomly selected prospective and actually pregnant women with a zinc-Amino-acid complex (Zn-AA), during pregnancy and early lactation, and compare the rate of ASD in their offspring with the rate in a similar and also randomly selected cohort of non supplemented women, to assess if Zn-AA supplementation during pregnancy has any effect on this outcome

NCT ID: NCT04950855 Terminated - Pregnancy Related Clinical Trials

Retinal and Choroidal Microvascular Changes During Pregnancy Period Detected With Optical Coherence Tomography Angiography

Start date: June 26, 2021
Phase:
Study type: Observational

During pregnancy many physiological changes and adaptations occur.Hormonal, hematological and hemodynamic changes are responsible for most of the ocular adaptations.We are planning to compare the choroid and retinal blood flow values and choroidal thickness of pregnant women and healthy non pregnant women with optical coherence tomography and optic coherence tomography angiography

NCT ID: NCT04753957 Terminated - Pregnancy Related Clinical Trials

Pharmacokinetics of Progesterone in Pregnancy-2

PiP-2
Start date: January 7, 2022
Phase: Phase 1
Study type: Interventional

The objective of this study is to evaluate the local pharmacokinetics of progesterone in pregnancy through evaluation of progesterone levels in maternal serum, endometrium, and cordblood in pregnant patients undergoing scheduled cesarean delivery.

NCT ID: NCT04725812 Terminated - Pregnancy Related Clinical Trials

Complement Regulation to Undo Systemic Harm in Preeclampsia

CRUSH
Start date: September 13, 2021
Phase: Phase 2
Study type: Interventional

This is a Phase II, single arm, open-label study to determine if treatment with eculizumab prolongs pregnancy compared to historical controls in women with preeclampsia between 23-30 weeks gestation.

NCT ID: NCT04594070 Terminated - Pregnancy Related Clinical Trials

Daily Versus Alternate Day Iron Supplementation for the Treatment of Iron Deficiency Anemia in Pregnancy

Start date: October 27, 2020
Phase: Phase 4
Study type: Interventional

The target population for our study is pregnant women in the first or second trimester with a diagnosis of iron deficiency anemia. If a subject is eligible, written consent will be obtained by person to person contact. Eligible participants will be randomized to receive either daily oral iron supplementation or every other day oral iron supplementation.

NCT ID: NCT04116749 Terminated - Pregnancy Related Clinical Trials

Gastric Emptying of Water in Obese Term Pregnant Women

Start date: November 27, 2019
Phase:
Study type: Observational

It has been believed that the risk of pulmonary aspiration in term pregnant women is increased, and should be considered that all term pregnant women to have "full stomach". Recently, gastric ultrasound has been adopted as a useful tool for quantitative and qualitative assessment of stomach before anesthesia, and predict the risk of pulmonary aspiration. Although, both the obesity and pregnancy are known to be the risk of pulmonary aspiration, it is suggested in the American Society of Anesthesiology fasting guidelines, that the same fasting time should be applied in the obese and non-obese parturients. However, this was based on one study done in a small (10) numbers of volunteers. Therefore, the investigators aimed to compare the gastric antral cross-sectional area in both obese and non-obese term pregnant women, scheduled for elective cesarean section.

NCT ID: NCT04084990 Terminated - Clinical trials for Obstructive Sleep Apnea

Sleep Apnea and Fetal Growth Restriction

SAFER
Start date: November 18, 2019
Phase: Phase 3
Study type: Interventional

This study aims to evaluate the association between obstructive sleep apnea (OSA) and fetal growth restriction (FGR) and to assess the role of auto-titrated positive airway pressure (aPAP) as antenatal therapy in these patients. Pregnant patients with diagnosed FGR will be screened for OSA first by screening questionnaire and then by home sleep monitor. Of those patients diagnosed with OSA, half will be assigned to use aPAP each night when sleeping and half will not (standard care).

NCT ID: NCT04052347 Terminated - Pregnancy Related Clinical Trials

Decision Aid to Assist Low-Risk Nulliparous Women Considering Induction of Labor At 39 Weeks

DAWN
Start date: November 25, 2019
Phase: N/A
Study type: Interventional

The primary objective is to assess if the utilization of a decision-aid increases the likelihood of low-risk nulliparous women undergoing elective induction of labor at 39.0-39.6 weeks