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Pregnancy Related clinical trials

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NCT ID: NCT05271877 Not yet recruiting - Pregnancy Related Clinical Trials

Evaluation of Surgical and Obstetric Outcomes in Pregnant Women Undergoing Operative Laparoscopy

Start date: December 2022
Phase:
Study type: Observational

Laparoscopy, when applicable, is the current gold standard management for abdominal and pelvic surgery. Although accumulating evidence suggests that laparoscopy is associated with reduced intraoperative and postoperative morbidity, reduced hospital stay, better recovery and cosmesis compared with open surgery (laparotomy), the use of this technique in pregnant women is still debated. Considering this point, we aimed to collect retrospectively cases of laparoscopic surgery during pregnancy, regardless of the indication and gestational age, in order to analyze both surgical and obstetric outcomes during and after the procedure.

NCT ID: NCT05262738 Completed - Obesity Clinical Trials

Misoprostol Dosing in BMI Greater Than 30

MD30 RCT
Start date: June 1, 2022
Phase: Phase 4
Study type: Interventional

The investigators are performing a randomized controlled-trial investigating if 50mcg (compared to 25 mcg) of vaginal misoprostol reduces the time from induction start to delivery in obese women.

NCT ID: NCT05258786 Completed - Pregnancy Related Clinical Trials

Pre-labor Ultrasound as a Visual Biofeedback Device for Maternal Pushing Education

Start date: February 18, 2022
Phase: N/A
Study type: Interventional

The study will observe the effect of antenatal biofeedback with transperineal and abdominal ultrasound applied by a pelvic floor physical therapist. The training will focus on pelvic floor training and maternal-coached pushing with ultrasound-based visual biofeedback. The investigators aim to assess maternal and neonatal obstetrical outcomes, urinary and fecal incontinence, and maternal psychological effects.

NCT ID: NCT05256615 Recruiting - Diabetes Clinical Trials

Exercise Timing and Gestational Diabetes

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to understand if the timing of exercise around food intake can help improve blood sugar management in pregnant individuals with diabetes.

NCT ID: NCT05253742 Not yet recruiting - Pregnancy Related Clinical Trials

Fetal MRI Acquisition and Sequence Development

FMASD
Start date: May 31, 2023
Phase:
Study type: Observational

Testing of new magnetic resonance imaging (MRI) pulse sequences (image acquisition software) for imaging the fetus to improve workflow and image quality in fetal imaging and diagnosis. The investigators would like to develop novel MRI approaches to enhance fetal imaging with MRI, in the presence of motion. As part of technical development, the investigators plan to develop methods to improve structural T1 and T2 weighted images, MR angiography, diffusion and spectroscopy measurements of the fetus.

NCT ID: NCT05250479 Recruiting - Pregnancy Related Clinical Trials

Effect of Mindfulness Education in Primiparous Pregnant Women

Start date: December 20, 2021
Phase: N/A
Study type: Interventional

While adaptation is generally achieved to the psychological changes that develop during pregnancy, some women may experience psychological changes such as contradiction, uncertainty, introversion, passive personality, addiction, fear, and anxiety in different periods of pregnancy. During this period, the fear of childbirth may also be experienced in pregnant women. Fear of childbirth or tokophobia is a phobic condition in which a woman avoids giving birth despite desperately wanting a baby. While fear of childbirth can have a negative impact on women's psychological health during pregnancy and birth experience, it is associated with negative obstetric outcomes and postpartum mental health problems. It is possible that the fear of childbirth reduces the mother's attachment to the fetus. Fear increases avoidant attachment and anxiety, which may be associated with lower commitment scores. There is a strong relationship between fear of childbirth and negative birth outcomes. Both affect the psychological well-being of the mother, adjustment to motherhood, and the quality of the mother's relationship with the baby. Knowing the fear of childbirth is important as it is associated with various health problems such as certain physiological and obstetric disorders and they can increase the possibility of emergency cesarean section. Mindfulness-based interventions combine elements of established cognitive behavioral therapy and psychoeducational content to support a self-effective approach to reduce stress-related symptoms and improve mental and physical well-being. Mindfulness-based practices that involve focusing on the present moment and accepting life without judgment are one of the effective ways to prepare for childbirth, help women feel more empowered and aware of their motherhood processes, and give mothers the opportunity to share knowledge and emotions. Mindfulness-based birth education intervention appears to be applicable for women and is associated with improvements in women's sense of control and confidence in giving birth.

NCT ID: NCT05250297 Completed - Pregnancy Related Clinical Trials

Physical Activity and Symptom Disturbance Regarding Cross-Trimester

Start date: May 14, 2018
Phase:
Study type: Observational [Patient Registry]

This study will explore pregnant women's regular exercise intentions and behavior across trimesters (from first trimester, second trimester to third trimester).

NCT ID: NCT05245734 Recruiting - Pregnancy Related Clinical Trials

Human Anti-D (rh) Immunoglobulin (Rhesoglobin) Efficacy, Safety and Some Pharmacokinetics Parameters in Pregnant Women

Start date: February 8, 2022
Phase: Phase 4
Study type: Interventional

Rhesus conflict between mother and fetus is due to the different antigenic composition of erythrocytes. During the first pregnancy, sensitization of the mother to fetal erythrocytes rhesus D (RhD) antigens is formed. During the next pregnancy, fetal red blood cells are attacked by the mother's antibodies, and fetal/newborn hemolytic disease develops. The drug Rhesoglobin blocks the interaction of the fetal erythrocytes RhD antigen and the immune system of the mother and prevents the development of Rhesus sensitization.

NCT ID: NCT05245266 Recruiting - Pregnancy Related Clinical Trials

Cell-Based Noninvasive Prenatal Testing

NIPT
Start date: January 12, 2022
Phase: N/A
Study type: Interventional

The purpose of the overall study is to develop improved methods for recovery and analysis of fetal cells from the mother's blood in order to develop clinically useful forms of cell-based, diagnostic, noninvasive prenatal testing (NIPT). Luna genetics will obtain and analyze research blood samples from healthy pregnant women. A phlebotomist will be sent to any location in the United States to collect the blood samples. Sample identifiers will be removed as the first step so that laboratory personnel will not see or have access to identifiers.

NCT ID: NCT05234125 Recruiting - Pregnancy Related Clinical Trials

Better Lifestyle Counseling for African American Women During Pregnancy

BETTER
Start date: August 16, 2022
Phase: N/A
Study type: Interventional

The purpose of this randomized controlled trial is to establish the effectiveness of a culturally targeted and individually tailored behavioral intervention to promote maternal glucose metabolism in African American women.