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Post-Operative Delirium clinical trials

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NCT ID: NCT03212300 Withdrawn - Clinical trials for Post-operative Delirium

Exercise "Prehabilitation" and Cognitive and Functional Recovery After Surgery in Older Adults

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

This is a randomized study to examine whether aerobic exercise training (AET) before total shoulder replacement (TSR) surgery reduces the incidence of post-operative delirium (POD) and shorten time to recovery in elderly patients. POD is a form of sudden change in mental function that could be experienced after undergoing surgery.

NCT ID: NCT03132168 Recruiting - Clinical trials for Post-operative Delirium

Postoperative Delirium in Patients Undergoing Radical Cystectomy

Start date: August 2016
Phase: N/A
Study type: Interventional

In this study, post-operative delirium will be measured in patients undergoing surgery for bladder resection, and associated microRNA biomarkers will be evaluated in patients considered delirious and non-delirious after surgery.

NCT ID: NCT03053869 Recruiting - Clinical trials for Post-operative Delirium

Benzodiazepine-free Anesthetic for Reduction of Delirium (B-Free)

B-Free
Start date: April 1, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this two-centre pilot research study is to establish the feasibility of conducting a full trial that seeks to determine if a cardiac anesthesia policy that uses alternatives to benzodiazepine medications is better at preventing delirium after cardiac surgery when compared with a cardiac anesthesia policy that uses benzodiazepine medications.

NCT ID: NCT02692300 Recruiting - Clinical trials for Post-operative Delirium

EEG Guidance of Anesthesia (ENGAGES-CANADA)

ENGAGES
Start date: February 2016
Phase: N/A
Study type: Interventional

This study examines the potential link between deep levels of anesthesia and delirium.

NCT ID: NCT02325154 Completed - Clinical trials for Post-operative Delirium

Cerebral Oxygenation in Total Hip Arthroplasty Patients

THANIRS
Start date: December 2014
Phase:
Study type: Observational

We plan to investigate the relationship between hypotensive epidural anesthesia for hip arthroplasty and cerebral oxygen saturation.

NCT ID: NCT02213380 Recruiting - Clinical trials for Post Operative Delirium

Effect of Anesthesia on Post-operative Delirium in Elderly Patients Undergoing Hip Fracture Surgery

RAGADelirium
Start date: September 2014
Phase: N/A
Study type: Interventional

The purpose of this study is evaluate postoperative delirium after general anesthesia and regional anesthesia in elderly patients undergoing hip fracture surgery. Our research hypotheses are: (1) regional anesthesia may contribute to decrease the incidence of postoperative delirium. (2) Regional anesthesia may improve the outcome of elderly patient and reduce healthcare costs associated with postoperative delirium. (3) Postoperative delirium may result in poor long-term functional outcomes.

NCT ID: NCT01993992 Active, not recruiting - Anxiety Clinical Trials

Parental Anxiety and Its Relationship With Pediatric Patients' Post-operative Responses

Start date: December 2013
Phase: N/A
Study type: Observational

Post-operative delirium had multiple risk factors, such as pre-operative anxiety status, post-operative pain, and anesthetic method. We currently decrease pre-operative anxiety by parental accompanying until the children put to sleep. However, references indicate that parental anxiety can increase the post-operative delirium. Heart rate variability was used to measure the anxiety status of parents. We think sympathetic tone elevation measured by heart rate variability may not induce by anxiety alone, thus we want to explore this question by using Stat-Trait Anxiety Inventory questionnaire.

NCT ID: NCT01561378 Completed - Clinical trials for Post-operative Delirium

Cardiac Surgery Neuroprotection Study in Elders

CNS-Elders
Start date: August 2012
Phase: Phase 2
Study type: Interventional

The goal of this study is to determine the potential ability of intranasal insulin to prevent post-operative cognitive decline and post-operative delirium in an elderly cardiac surgery population.

NCT ID: NCT00991328 Terminated - Clinical trials for Postoperative Cognitive Dysfunction

Role of Absolute Cerebral Oximetry to Prevent Neurocognitive Injury in Elderly Patients Undergoing Cardiac Surgery

Start date: September 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether brain oxygenation measured by cerebral oximeter has an impact on neurocognitive dysfunction.

NCT ID: NCT00865202 Completed - Clinical trials for Post-operative Delirium

A Placebo Controlled Trial Of L-Tryptophan In Post-Operative Delirium

Start date: December 2008
Phase: Phase 3
Study type: Interventional

Post-operative delirium is a common and deleterious complication in elderly patients. The investigators have previously found lower levels of serum tryptophan in post-operative elderly patients who developed delirium in comparison to post-operative elderly patients who did not develop delirium. The investigators hypothesize that post-operative supplementation of L-tryptophan will reduce the duration and incidence of post-operative delirium. This study is a double-blinded placebo controlled trial of L-tryptophan supplementation in post-operative ICU patients 60 years and older. The primary outcome measure is the comparison of duration of post-operative delirium in subjects who receive L-tryptophan supplementation versus a similar appearing control.