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Post-Operative Delirium clinical trials

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NCT ID: NCT05159648 Completed - Clinical trials for Post-Operative Delirium

A Study to Evaluate ICU Simulation Experience in the Cardiothoracic Surgical Population to Reduce Post-operative Delirium

Start date: December 2, 2021
Phase:
Study type: Observational

The purpose of this study is to evaluate the effect of a pre-ICU admission virtual reality ICU simulation on post-operative delirium in the elective cardiothoracic surgical population while in the intensive care unit.

NCT ID: NCT04797052 Completed - Clinical trials for Post Operative Delirium

EEG Detection of Delirium

VEEGilance
Start date: April 5, 2021
Phase: N/A
Study type: Interventional

VEEGix is a portable device developed by NeuroServo for simplifying electroencephalograms at the bedside. It is an easy-to-use device that only requires the operator to place an adhesive strip of electrodes on the patient's forehead, connected to the device. The goal of this study is to determine EEG thresholds for the diagnostic of delirium. Methods : This prospective observational study includes patients undergoing orthopedic or degestive surgery. Each subject will have an EEG reading before surgery and twice daily after surgery until discharge or up to 5 days. Patients will be monitored for post operative delirium using the 3D-Confusion Assessment Method. Delirium diagnostic will be confirmed by a geriatrician. EEG relative power reading will be compared between patient with and without a delirium diagnostic.

NCT ID: NCT03953313 Completed - Clinical trials for Post-operative Delirium

Risk Communication About Post-operative Delirium (POD) and Post-operative Cognitive Dysfunction (POCD)

Start date: May 3, 2021
Phase:
Study type: Observational

The purpose of this study is to assess the awareness of post-operative delirium (POD) and post-operative cognitive dysfunction (POCD), their respective risk factors and effective preparation and treatment options in a pre-clinical sample of patients attending a premedication outpatient clinic (Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany) prior to elective surgery. The investigators hypothesize that the awareness for POD/POCD as potential risk in consequence of the surgery is very low in patients, and that therefore easy to use measure for prevention are underutilized by patients.

NCT ID: NCT03785158 Active, not recruiting - Clinical trials for Post-operative Delirium

MIND After Surgery

MIND
Start date: September 14, 2021
Phase: N/A
Study type: Interventional

Delirium is the most common neurological adverse outcome in elderly surgical patients. It is associated with an increased mortality and morbidity, including need for prolonged hospital stay and institutional care. Despite this, there are no effective preventive strategies. Melatonin is a hormone released from the pineal gland. It is used to improve sleep quality and to treat jet lag. Small studies have suggested that it can decrease the chances of delirium. Since the existing literature is small and uncertain, it is important to test its benefit in a large sample to help guide clinicians. This proposed trial is aimed at testing assessing the feasibility of a large, multi-center, randomized control trial to decrease the incidence of postoperative delirium.

NCT ID: NCT03132168 Completed - Clinical trials for Post-operative Delirium

Postoperative Delirium in Patients Undergoing Radical Cystectomy

Start date: January 10, 2018
Phase: N/A
Study type: Interventional

In this study, post-operative delirium will be measured in patients undergoing surgery for bladder resection, and associated microRNA biomarkers will be evaluated in patients considered delirious and non-delirious after surgery.

NCT ID: NCT03053869 Completed - Clinical trials for Post-operative Delirium

Benzodiazepine-free Anesthetic for Reduction of Delirium (B-Free)

B-Free
Start date: April 1, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this two-centre pilot research study is to establish the feasibility of conducting a full trial that seeks to determine if a cardiac anesthesia policy that uses alternatives to benzodiazepine medications is better at preventing delirium after cardiac surgery when compared with a cardiac anesthesia policy that uses benzodiazepine medications.

NCT ID: NCT02692300 Completed - Clinical trials for Post-operative Delirium

EEG Guidance of Anesthesia (ENGAGES-CANADA)

ENGAGES
Start date: December 28, 2016
Phase: N/A
Study type: Interventional

This study examines the potential link between deep levels of anesthesia and delirium.

NCT ID: NCT02325154 Completed - Clinical trials for Post-operative Delirium

Cerebral Oxygenation in Total Hip Arthroplasty Patients

THANIRS
Start date: December 2014
Phase: N/A
Study type: Interventional

We plan to investigate the relationship between hypotensive epidural anesthesia for hip arthroplasty and cerebral oxygen saturation.

NCT ID: NCT02213380 Completed - Clinical trials for Post Operative Delirium

Effect of Anesthesia on Post-operative Delirium in Elderly Patients Undergoing Hip Fracture Surgery

RAGADelirium
Start date: September 2014
Phase: N/A
Study type: Interventional

The purpose of this study is evaluate postoperative delirium after general anesthesia and regional anesthesia in elderly patients undergoing hip fracture surgery. Our research hypotheses are: (1) regional anesthesia may contribute to decrease the incidence of postoperative delirium. (2) Regional anesthesia may improve the outcome of elderly patient and reduce healthcare costs associated with postoperative delirium. (3) Postoperative delirium may result in poor long-term functional outcomes.

NCT ID: NCT01993992 Active, not recruiting - Anxiety Clinical Trials

Parental Anxiety and Its Relationship With Pediatric Patients' Post-operative Responses

Start date: December 2013
Phase: N/A
Study type: Observational

Post-operative delirium had multiple risk factors, such as pre-operative anxiety status, post-operative pain, and anesthetic method. We currently decrease pre-operative anxiety by parental accompanying until the children put to sleep. However, references indicate that parental anxiety can increase the post-operative delirium. Heart rate variability was used to measure the anxiety status of parents. We think sympathetic tone elevation measured by heart rate variability may not induce by anxiety alone, thus we want to explore this question by using Stat-Trait Anxiety Inventory questionnaire.