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Post-Operative Delirium clinical trials

View clinical trials related to Post-Operative Delirium.

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NCT ID: NCT05159648 Completed - Clinical trials for Post-Operative Delirium

A Study to Evaluate ICU Simulation Experience in the Cardiothoracic Surgical Population to Reduce Post-operative Delirium

Start date: December 2, 2021
Phase:
Study type: Observational

The purpose of this study is to evaluate the effect of a pre-ICU admission virtual reality ICU simulation on post-operative delirium in the elective cardiothoracic surgical population while in the intensive care unit.

NCT ID: NCT04797052 Completed - Clinical trials for Post Operative Delirium

EEG Detection of Delirium

VEEGilance
Start date: April 5, 2021
Phase: N/A
Study type: Interventional

VEEGix is a portable device developed by NeuroServo for simplifying electroencephalograms at the bedside. It is an easy-to-use device that only requires the operator to place an adhesive strip of electrodes on the patient's forehead, connected to the device. The goal of this study is to determine EEG thresholds for the diagnostic of delirium. Methods : This prospective observational study includes patients undergoing orthopedic or degestive surgery. Each subject will have an EEG reading before surgery and twice daily after surgery until discharge or up to 5 days. Patients will be monitored for post operative delirium using the 3D-Confusion Assessment Method. Delirium diagnostic will be confirmed by a geriatrician. EEG relative power reading will be compared between patient with and without a delirium diagnostic.

NCT ID: NCT03953313 Completed - Clinical trials for Post-operative Delirium

Risk Communication About Post-operative Delirium (POD) and Post-operative Cognitive Dysfunction (POCD)

Start date: May 3, 2021
Phase:
Study type: Observational

The purpose of this study is to assess the awareness of post-operative delirium (POD) and post-operative cognitive dysfunction (POCD), their respective risk factors and effective preparation and treatment options in a pre-clinical sample of patients attending a premedication outpatient clinic (Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany) prior to elective surgery. The investigators hypothesize that the awareness for POD/POCD as potential risk in consequence of the surgery is very low in patients, and that therefore easy to use measure for prevention are underutilized by patients.

NCT ID: NCT03132168 Completed - Clinical trials for Post-operative Delirium

Postoperative Delirium in Patients Undergoing Radical Cystectomy

Start date: January 10, 2018
Phase: N/A
Study type: Interventional

In this study, post-operative delirium will be measured in patients undergoing surgery for bladder resection, and associated microRNA biomarkers will be evaluated in patients considered delirious and non-delirious after surgery.

NCT ID: NCT03053869 Completed - Clinical trials for Post-operative Delirium

Benzodiazepine-free Anesthetic for Reduction of Delirium (B-Free)

B-Free
Start date: April 1, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this two-centre pilot research study is to establish the feasibility of conducting a full trial that seeks to determine if a cardiac anesthesia policy that uses alternatives to benzodiazepine medications is better at preventing delirium after cardiac surgery when compared with a cardiac anesthesia policy that uses benzodiazepine medications.

NCT ID: NCT02692300 Completed - Clinical trials for Post-operative Delirium

EEG Guidance of Anesthesia (ENGAGES-CANADA)

ENGAGES
Start date: December 28, 2016
Phase: N/A
Study type: Interventional

This study examines the potential link between deep levels of anesthesia and delirium.

NCT ID: NCT02325154 Completed - Clinical trials for Post-operative Delirium

Cerebral Oxygenation in Total Hip Arthroplasty Patients

THANIRS
Start date: December 2014
Phase: N/A
Study type: Interventional

We plan to investigate the relationship between hypotensive epidural anesthesia for hip arthroplasty and cerebral oxygen saturation.

NCT ID: NCT02213380 Completed - Clinical trials for Post Operative Delirium

Effect of Anesthesia on Post-operative Delirium in Elderly Patients Undergoing Hip Fracture Surgery

RAGADelirium
Start date: September 2014
Phase: N/A
Study type: Interventional

The purpose of this study is evaluate postoperative delirium after general anesthesia and regional anesthesia in elderly patients undergoing hip fracture surgery. Our research hypotheses are: (1) regional anesthesia may contribute to decrease the incidence of postoperative delirium. (2) Regional anesthesia may improve the outcome of elderly patient and reduce healthcare costs associated with postoperative delirium. (3) Postoperative delirium may result in poor long-term functional outcomes.

NCT ID: NCT01561378 Completed - Clinical trials for Post-operative Delirium

Cardiac Surgery Neuroprotection Study in Elders

CNS-Elders
Start date: August 2012
Phase: Phase 2
Study type: Interventional

The goal of this study is to determine the potential ability of intranasal insulin to prevent post-operative cognitive decline and post-operative delirium in an elderly cardiac surgery population.

NCT ID: NCT00865202 Completed - Clinical trials for Post-operative Delirium

A Placebo Controlled Trial Of L-Tryptophan In Post-Operative Delirium

Start date: December 2008
Phase: Phase 3
Study type: Interventional

Post-operative delirium is a common and deleterious complication in elderly patients. The investigators have previously found lower levels of serum tryptophan in post-operative elderly patients who developed delirium in comparison to post-operative elderly patients who did not develop delirium. The investigators hypothesize that post-operative supplementation of L-tryptophan will reduce the duration and incidence of post-operative delirium. This study is a double-blinded placebo controlled trial of L-tryptophan supplementation in post-operative ICU patients 60 years and older. The primary outcome measure is the comparison of duration of post-operative delirium in subjects who receive L-tryptophan supplementation versus a similar appearing control.