Clinical Trials Logo

Periodontal Diseases clinical trials

View clinical trials related to Periodontal Diseases.

Filter by:

NCT ID: NCT06296498 Recruiting - Clinical trials for Periodontal Diseases

Application of L-PRF in Periodontal Surgery

Start date: August 19, 2023
Phase: N/A
Study type: Interventional

The study will compare the clinical outcomes of the two procedures, open flap debridement (OFD) compared to open flap debridement with leukocyte and platelet-rich fibrin (L-PFR) as well as differences in patient postoperative pain perception.

NCT ID: NCT06293807 Completed - Clinical trials for Periodontal Diseases

Immediate Post-Operative Anesthesia With Either Lidocaine or Bupivacaine

Start date: June 6, 2022
Phase: Early Phase 1
Study type: Interventional

Immediate post-suturing administration of either one of two dental anesthetic solutions or a placebo prior to dismissal.

NCT ID: NCT06291454 Completed - Clinical trials for Periodontal Diseases

GCF Levels of Chemokines in Periodontitis

Start date: January 1, 2023
Phase:
Study type: Observational [Patient Registry]

This study aimed to determine CCL19/MIP3beta(β) and CCL20/MIP3alpha(α) in the gingival crevicular fluid (GCF) of the patients with different periodontitis phenotypes. A total of 72 individuals, 24 with Stage III Grade B periodontitis (Group 1), 24 with Stage III Grade C periodontitis (Group 2), and 24 periodontally healthy (control group) (Group 3), were included in the study. GCF and clinical periodontal parameters were obtained at baseline. MIP3β and MIP3α levels in GCF were determined by ELISA.

NCT ID: NCT06291129 Active, not recruiting - Diabetes Clinical Trials

Gingival Health and Malocclusion Among Type 1 Diabetic Children and Adolescents

Start date: October 30, 2022
Phase: N/A
Study type: Interventional

Introduction: This study aims to evaluate the gingivitis, periodontal profile and malocclusion in children and adolescents with diabetes. Methods: The sample consisted of 36 children, who were distributed into two groups: DM; n=18 and NDM; n=18. Periodontal parameters considered were plaque Index (PI), gingival Index (GI), probing depth of pocket (PPD), gingival recession (GR) and clinical attachment level (CAL). Gingival biotype clinical parameters: Gingival transparency to probing, Height of keratinized mucosa and Gingival thickness on permanent incisors and molars. Malocclusion were evaluated by the Dental Aesthetic Index (DAI) and the Angle's Classification. The statistical analyses were Shapiro Wilk test and T test.

NCT ID: NCT06290414 Recruiting - Clinical trials for Periodontal Diseases

The Accuracy of Infrared Thermographic Imaging for Assessment of Periodontal Status

Start date: November 30, 2023
Phase:
Study type: Observational [Patient Registry]

The diagnosis and differentiation between periodontal diseases are currently based on the measuring and interpretation of full-mouth clinical and radiographic criteria. Thermography is a modern non-invasive imaging method in which the infrared radiation emitted by an object allows the mapping and analysis of the exact temperature distribution on the surface of the object. The produced thermal images correlate with variations in local blood supply and tissue metabolism. Thus, suggested to be a useful rapid and non-invasive tool for the diagnosis of periodontal diseases. However, the validity of this tool compared to standard tools should be evaluated.

NCT ID: NCT06261723 Recruiting - Clinical trials for Periodontal Diseases

Effect of Non-chirurgical Periodontal Treatment on the Immune System From a Gender Perspective

Start date: February 15, 2024
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to evaluate non-surgical periodontal treatment in women and men with periodontitis with and without obesity. The main questions it aims to answer are: - If non-surgical periodontal treatment of patients with chronic periodontitis can modulate the innate and adaptive immune response taking into account patient gender and the coexistence of obesity - If there are specific miRNAs that can regulate this immune response and can be considered as suitable biomarkers and therapeutic targets. Obese or non-obese participants with periodontitis will receive non-surgical periodontal treatment, consisting of oral health guidance and mechanical periodontal debridement throughout the mouth using an ultrasonic device and manual curettes. Researchers will compare four groups: obese women, non-obese women, obese men, and non-obese men, to clarify the involment of immune response after treatment, considering the coexistence of obesity and potential gender differences.

NCT ID: NCT06253988 Completed - Clinical trials for Periodontal Diseases

Effect of Probiotics on Periodontitis Stage III Grade C Molar-incisor Pattern

RCT
Start date: January 1, 2023
Phase: Phase 3
Study type: Interventional

the research highlight the effectiveness of probiotics as adjuncts to SRP in the treatment of periodontitis stage III grade C molar-incisor pattern

NCT ID: NCT06253910 Terminated - Clinical trials for Periodontal Diseases

Comparison of Free Gingival Graft and Modified Apical Repositioning Flap Techniques

Start date: February 15, 2019
Phase: N/A
Study type: Interventional

Attached gingiva, a crucial component of the keratinized tissue, plays a vital role in preserving periodontal health. The free gingival graft (FGG) and modified apically repositioned flap (MARF) techniques are frequently used for addressing issues related to insufficient attached gingiva. The aim of this study was to compare the efficiency of the FGG and the MARF increasing the zone of attached gingiva in 2-year posttreatment.

NCT ID: NCT06250764 Completed - Obesity Clinical Trials

Asprosin, Adropin, Irisin Levels in Periodontitis

Start date: February 12, 2020
Phase:
Study type: Observational [Patient Registry]

The recently discovered association of the hormones 'asprosin, adropin and irisin' with obesity and metabolic status, as well as the fact that periodontal diseases are affected by obesity and nutrition bilaterally, have led us to investigate the relationship between selected target markers and periodontal disease. The primary aim and main objective of this study is to increase the knowledge and to direct future researches as a result of the lack of adequate research in the past and the very limited investigations with these hormones in dentistry and periodontology. Our study was conducted on 122 patients who applied to Adıyaman University Faculty of Dentistry and were referred to the Department of Periodontology for routine periodontal controls. Participants' gender, age, height, weight, BMI, education level, tooth brushing and flossing habits as well as clinical parameters PI, GI, SCD, CAS and SDI were noted. Participants were divided into 4 groups as healthy, gingivitis, initial periodontitis and advanced periodontitis and grouped according to the current periodontal classification of 2017. DOS was collected from the groups for examination and 'asprosin, adropin and irisin' values in the samples were evaluated by ELISA test.

NCT ID: NCT06247007 Completed - Periodontitis Clinical Trials

Electroacupuncture as an Adjunct to Non-Surgical Periodontal Therapy

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

The aim of this randomized, single-masked, controlled clinical trial study was to determine if the administration of electro acupuncture improves the outcomes obtained in combination with non-surgical periodontal therapy. Participants will get non-surgical periodontal therap with/without electro acupuncture. Researchers will compare EA and control groups to see if there is any relationship between acupuncture application clinical periodontal parameters,serum and saliva cytokine levels.