Clinical Trials Logo

Periodontal Diseases clinical trials

View clinical trials related to Periodontal Diseases.

Filter by:

NCT ID: NCT06316505 Completed - Clinical trials for Periodontal Diseases

Oral Photographs of Patients on Oral Hygiene Motivation

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

Based on these considerations, this randomized controlled trial aimed to determine the effectiveness of a personalized visual oral health education program in addition to conventional education on oral hygiene by comparing changes in clinical periodontal parameters. Participants will get conventional oral hygiene education (COHE) with/without visual motivation using self oral photographs of patients. Researchers will compare Intervention group and control groups on oral hygiene by comparing changes in clinical periodontal parameters.

NCT ID: NCT06315855 Not yet recruiting - Cancer Clinical Trials

Leveraging Telehealth to Improve Oral Health Among Cancer Survivors

Start date: March 25, 2024
Phase: N/A
Study type: Interventional

The investigators will conduct a 2-arm 6-month randomized clinical controlled trial to evaluate the effectiveness of an oral Telehealth Intervention (THI) in preventing cancer-related oral complications, improving oral health maintenance and oral health related quality of life, and reducing systemic inflammation compared to Usual Care (UC) among unselected cancer survivors.

NCT ID: NCT06315088 Not yet recruiting - Clinical trials for Periodontal Diseases

Food Biodiversity and Human Health

BIOQUALIM
Start date: October 1, 2024
Phase: N/A
Study type: Interventional

In Western countries, one of the major nutritional challenges requires reducing the proportion of animal proteins and increasing the proportion of vegetable proteins in the daily plate. Added to this nutritional challenge is an environmental challenge, with plant proteins being much less expensive to produce. However, plant proteins are mainly provided by cereals and legumes, a large diversity of which is necessary to cover the recommended daily intake of amino acids. However, given the collapse of cultivated biodiversity (loss of 75% in 100 years, FAO), the diversity of the supply is very reduced. Furthermore, for several years, public health studies have indicated a chronic deficit in micronutrients (minerals/trace elements, vitamins, antioxidants) as well as fiber in the diet of the French population. This comes in particular from the impoverishment of the nutritional quality of the fruits/vegetables/cereals/legumes consumed. In general, diet plays a major role in the primary prevention of chronic diseases (cardiovascular, diabetes, cancer) including periodontal disease. Thus, a diet low in sugars, saturated fats and rich in fiber would reduce the appearance of periodontal disease by strengthening salivary capacity. However, certain pathogenic periodontal bacteria (such as Porphyromonas gingivalis) can migrate (blood, digestive or respiratory routes) to reach other organs and represent a risk factor for other chronic diseases. Thus, the prevention of periodontal diseases through diet control would also contribute to the prevention of other chronic diseases. The benefit of plant-based diets to reduce the risk of cancer is now established. In addition, certain cereals such as spelled have superior nutritional qualities to common wheat, notably their protein content and they also contain higher quantities of certain bioactive compounds with anti-cancer properties (such as phytosterols). Furthermore, the potential impact of the oral microbiota on chronic diseases is now being studied: in healthy adults, a dysbiotic periodontal microbiota may be likely to lead to systemic para-inflammation. It has also been shown that a dietary change (Mediterranean diet) could lead to a reduction in pathogenic bacteria in the oral microbiota (including P. gingivalis). However, the link between the introduction of cereals into the diet and the evolution of cancer risk factor bacteria in the oral microbiota has never been demonstrated. This pilot clinical study plans to focus on the oral microbiota, with the aim of objectivizing a possible link between a modification of the diet by the introduction of cereals (einkorn type) and the evolution of certain bacteria of this microbiota. , notably P. gingivalis (but also T. forsythia, S. anginosus, A. actinomycetemcomitans, T. denticola and F. nucleatum), considered as cancer risk factors and thus observe an improvement in health status oral and general.

NCT ID: NCT06313216 Not yet recruiting - Clinical trials for Periodontal Diseases

Treatment of Peri-implant Bone Dehiscence Using Autogenous Tooth Plate

Start date: March 15, 2024
Phase: N/A
Study type: Interventional

The current trial aim was to evaluate clinically and radiographically the changes around dental implants inserted immediately in maxillary anterior esthetic zone using a novel combination of autogenous demineralized tooth graft. with autogenous demineralized tooth plate and compared this approach to autogenous demineralized tooth graft. The present study included 63 patients, aged 20 to 45, with teeth that needed to be extracted. After Kafrelsheikh University research ethics committee approval, patients were randomized into 3 groups: group I patients underwent immediate implantation with Duo-Teck membrane, while group II patients underwent the same procedure, but the dehisced bone defect was grafted by autogenous demineralized tooth graft. finally group III was grafted by combination of autogenous demineralized tooth graft. with autogenous demineralized tooth plate.

NCT ID: NCT06311253 Not yet recruiting - Clinical trials for Periodontal Diseases

Non-surgical Periodontal Treatment With Adjunctive Use of Lactoferrin Contained in Toothpaste and Mouthwash

Start date: March 20, 2024
Phase: N/A
Study type: Interventional

The aim of the study is to assess the effect of lactoferrin in LBC complex can be effective in reducing periodontal clinical parameters in a 6-month study on pregnant patients.

NCT ID: NCT06309719 Not yet recruiting - Clinical trials for Periodontal Diseases

Hyaluronic Acid and Polynucleotides for Supra-bony Defects

Start date: May 2024
Phase: N/A
Study type: Interventional

The goal of this pilot study is to describe the early wound healing molecular events and the vascularization pattern associated with the treatment of supra-bony defects with access flap alone or in association with a combined formulation of hyaluronic acid and polydeoxyribonucleotides gel.

NCT ID: NCT06308497 Not yet recruiting - Pregnancy Related Clinical Trials

Adjunctive Periodontal Treatment With Coenzyme Q10 in Association With Probiotics for Pregnant Women

Start date: March 10, 2024
Phase: N/A
Study type: Interventional

The aim of the study is to assess if probiotic supplementation can be effective in reducing periodontal clinical parameters in a 6-month study on pregnant patients.

NCT ID: NCT06306937 Completed - Clinical trials for Periodontal Diseases

Serum Levels of Vitamin D and IL8 in Patients With Periodontitis

Start date: September 1, 2022
Phase:
Study type: Observational

We evaluated vitamin D and IL8 levels in the serum of patients with periodontitis as well as the healthy controls to correlate their levels with the degree of periodontitis.

NCT ID: NCT06306677 Recruiting - Periodontitis Clinical Trials

Accuracy of an AI-clinical Knowledge-based Hybrid System for Detecting Periodontitis in OPG Images

Start date: March 12, 2024
Phase:
Study type: Observational

Periodontitis is highly prevalent and rarely detected and treated in the earlier stages of the disease. Orthopantomography (OPG) is the most frequently taken dental radiograph around the world, and its systematic screening may contribute to early detection of periodontitis and access to the needed level of care. The investigators' recent study initially developed an AI-clinical knowledge-based system for automatic periodontitis diagnosis and indicated good performance for differentiating stage II-IV periodontitis. This cross-sectional diagnostic study aims to compare the diagnostic accuracy of this AI-clinical knowledge-based hybrid system (Index test) with human experts (reference test) for differentiating stage II-IV periodontitis using the OPG images obtained from different 4 centers around the world.

NCT ID: NCT06296498 Recruiting - Clinical trials for Periodontal Diseases

Application of L-PRF in Periodontal Surgery

Start date: August 19, 2023
Phase: N/A
Study type: Interventional

The study will compare the clinical outcomes of the two procedures, open flap debridement (OFD) compared to open flap debridement with leukocyte and platelet-rich fibrin (L-PFR) as well as differences in patient postoperative pain perception.