Osteoclast Impairment in Chronic Periodontitis by Regenerative Materials.

Status Completed

Clinical Trial Summary

The present study is an effort to investigate the hypothesis that Platelet Rich Fibrin/Biphasic Calcium Phosphate may play a role in inhibiting osteoclasts differentiation and in bone loss.

Clinical Trial Description

Study design

Fifty-five individuals from a suburban population were recruited. Out of them, 5 individuals refused to participate in the study. Finally, 50 participants were selected and divided into two groups, control group [Healthy individuals]: 25 Males/Females, aged 25 to 35 years and test group [Chronic periodontitis patients]: 25 Males/Females aged 30 to 45 years.

Demographic variables and periodontal parameters were measured in both the groups.The investigators explored the effect of Platelet rich fibrin (PRF)/Biphasic calcium phosphate (BCP) on differentiation and survival of osteoclasts obtained from peripheral blood of Chronic Periodontitis patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03227367
Study type	Interventional
Source	Meenakshi Ammal Dental College and Hospital
Contact
Status	Completed
Phase	N/A
Start date	March 17, 2014
Completion date	March 18, 2017

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