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Overweight clinical trials

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NCT ID: NCT03233906 Active, not recruiting - Obesity Clinical Trials

The Effects of Chia on Overweight/Obese Women

Start date: May 20, 2017
Phase: N/A
Study type: Interventional

The purpose of the study is to examine the effect of chia seed consumption on body composition, blood pressure, blood glucose, satiety, mood, joint pain, and dietary displacement in overweight and obese females (18-45years). It is hypothesized that consuming chia seeds will bring about a positive change in body composition (lower % body fat), satiety, mood, joint pain, and blood pressure, lower blood glucose levels, increased fiber and improved nutrient intake, in overweight/ obese females.

NCT ID: NCT03233568 Completed - Clinical trials for Overweight and Obesity

Use of Indirect Calorimetry in Obesity

Start date: April 1, 2012
Phase: N/A
Study type: Observational

The investigators will retrospectively analyze and compare data of 2 groups of overweight and obese patients: subjects who followed a diet based on Resting Energy Expenditure (REE) measured by indirect calorimetry and subjects who followed a diet based on REE estimated by the Harris-Benedict equation. Propensity score adjustment will be used to adjust for known differences between the 2 groups

NCT ID: NCT03233425 Completed - Overweight Clinical Trials

Evaluation of Multiprofessional Group Programs for Paediatric Obesity Therapy

KIDSSTEP
Start date: January 2009
Phase: N/A
Study type: Observational

The aim of this pilot project is to disseminate multiprofessional group programs (*MGP*) for therapy of the estimated 119'140 overweight/obese children in Switzerland. Family-based behavioral MGPs have been implemented from 2009 to 2013 to determine changes of health and family behaviours, after the intensive phase (*T1*), at 1 and 2 years after start (*T2*, *T3*). MGP costs are reimbursed in Switzerland: 1) if 116 sessions are provided by experts in physical activity, nutrition and psychology; 2) if parents are included and if their adherence is higher than 85%. In the nationwide "Evaluation of Multiprofessional Group Programs for Paediatric Obesity Therapy" (*KIDSSTEP*) study, multiple psychosocial and physical parameters were assessed at T0, T2 and T3 . Out of 33 certified centers, 25 were active and only 19 were re-certified in 2013/2014. Obese children suffer from major co-morbidities and therefore, only one third of referred patients can be treated in MGPs and their beneficial effects on obesity as well as physical and mental health outcomes are sustained over 2 years.

NCT ID: NCT03231618 Completed - Clinical trials for Healthy and Overweight/ Obesity Males

The Intervention Study of Dietary Intake on Energy Expenditure

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

This study is a randomized crossover (2 × 3) dietary intervention. 40 male volunteers(20 normal weight, 20 overweight / obesity, no other serious disease or metabolic abnormalities) aged 18-45 years are required to take 3 kinds of isocaloric diets with different amounts of macronutrients: low-fat high-carbohydrate diets, low-carbohydrate high-fat diets and high-protein low-fat diets. The comparison is made within subject before and after the test meal. Each subject takes 6 meals of 3 kinds of diets on 6 separate days with a washout period between different diets. The study protocol was approved by the Ethics Committee of Shanghai Institutes for Biological Sciences and all participants provided written informed consents. The study is the first to investigate among overweight / obesity and normal weight in China to clarify: 1. the relationship between the proportion of macronutrients in diets and the energy metabolism efficiency. 2. the main genetic and non-genetic factors that impact individual energy metabolism, the characteristics of metabolic profiling and relative regulatory pathways.

NCT ID: NCT03231592 Recruiting - Clinical trials for Overweight and Obesity

Im(Proving) the CSA Model

Start date: May 10, 2017
Phase: N/A
Study type: Interventional

In 1986, The Pioneer Valley in Western Massachusetts was home to one of the first two community supported agriculture (CSA) businesses in the USA. In 2014, there were 6,200 CSAs across the states, and today, in the Pioneer Valley alone, there are sixty CSAs. As with many parts of the United States, there are too many CSAs competing for the same pool of middle and upper-class customers. In his research at the University of Massachusetts in 2014, Mark Paul stated CSA farms are trapped in a lose-lose conundrum in which the farmers are not making enough money for a living wage, while simultaneously CSA shares are too expensive for many community members. The central challenge facing the CSA model moving forward is to provide fair compensation to farmers and farm workers, while making shares available at prices that can attract more members of the community. "(Im)Proving the CSA Model" proposes to increase consumption of and access to local products AND to develop new market opportunities for farms by opening the CSA membership base nationwide to low-income consumers and more price conscious middle class consumers. The investigators will do this by researching and documenting the health benefits of belonging to a CSA program. The investigators expect the resulting data to justify insurance-provided cash "wellness" benefits for CSA participation, much like those currently provided for gym membership. A wellness benefit will provide the financial incentive necessary to open CSA programs to lower- and middle-income consumers. The two-year research study intends to demonstrate that enrolling community health center patients in a Community Supported Agriculture (CSA) program is feasible and leads to dietary improvements that would be expected to offer clinical benefits in larger scale studies over longer timeframes. To maximize the knowledge gained from participation in this study, the investigators will measure several self-reported, laboratory, and clinical outcomes, but the primary purpose of this study is to provide pilot data for the model. To test this the investigators will implement a randomized controlled clinical trial design, with individual-level randomization of 120 participants, assigned in 1:1 ratio to receipt of a CSA membership (goal: 60 participants) or enhanced usual care (goal: 60 participants).

NCT ID: NCT03230383 Completed - Healthy Subjects Clinical Trials

A Study To Assess The Safety, Tolerability, And Pharmacokinetics (PK) Of Multiple Doses Of PF-06865571 In Healthy, Including Overweight And Obese, Adult Subjects

Start date: August 1, 2017
Phase: Phase 1
Study type: Interventional

This will be an investigator- and subject-blinded (sponsor open), randomized, placebo controlled, sequential, ascending, multiple oral dose study, with 5 planned cohorts (optional sixth and seventh cohorts). A total of approximately 50 (if 5 cohorts), 60 (if 6 cohorts), and up to 70 (if 7 cohorts) subjects will be randomized in this study. Subjects in each cohort will be randomized to receive PF-06865571 or matching placebo with approximately 10 subjects dosed in each cohort. For a given subject in any cohort, the total study duration from screening to follow-up phone call will be between approximately 7 to 11 weeks.

NCT ID: NCT03227276 Completed - Clinical trials for Overweight and Obesity

Efficacy and Safety of Litramine in 1 Year Weight Loss Study

Start date: August 14, 2017
Phase: N/A
Study type: Interventional

To evaluate the efficacy of Litramine in reducing body weight in the context of an energy-restricted diet in overweight and moderately obese subjects

NCT ID: NCT03223987 Recruiting - Overweight Clinical Trials

Influence of a Food Supplement on the Gut Microbiome in Healthy Obese Women

Start date: May 11, 2017
Phase: Early Phase 1
Study type: Interventional

Before and after study in obese women 25-35 years old, BMI 30-35, taking Strath® Kräuterhefe Original (liquid), Herbal Yeast Food Supplement for three weeks. At the beginning and after three weeks of the study a stool sample is provided. These samples are analysed with 16S rRNA analysis down to species level.The results are interpreted with the PICRUSt classification and Alpha Diversity Analysis and compared to internationally accepted data bases.

NCT ID: NCT03223935 Completed - Overweight Clinical Trials

Roasted Pulse Snacks, Post-prandial Food Intake, Appetite, and Glycemia

Start date: August 11, 2017
Phase: N/A
Study type: Interventional

An investigation on the effects of roasted pulse snacks on post-prandial glycemic and satiety response in healthy young adults.

NCT ID: NCT03223649 Completed - Healthy Clinical Trials

Break It Up: A Study Evaluating Breaking Up Daily Sedentary Behavior in Youth

Start date: July 26, 2017
Phase: Phase 2
Study type: Interventional

Background: Some studies have found that people can better process sugars when they take walking breaks. Studies have also found that children's attention and memory may improve after exercise. It is not known if short walking breaks have the same effects. Researchers want to study if breaking up sitting with walking for 6 days helps children s bodies use sugars and improves concentration. Objectives: To learn if breaking up sedentary (low-activity) time with short walking breaks over 6 days affects how children s bodies use sugar. To learn if breaking up sedentary time changes children s attention, memory, feelings, activity, or eating. Eligibility: Children ages 7-11 in general good health Design: Participants will be screened with: - Medical history - Physical exam - Fasting blood tests. On 2 out of 7 total study visits, participants cannot eat or drink after 10 p.m. the night before. - Full-body X-ray - EKG (Electronic signals that record heart function through stickers) - Treadmill exercise. Heart, blood pressure, and oxygen will be monitored. - Questions about the child s health, socialization, and activity, and parent s education and economic status - Picture vocabulary test - Dietician meeting (Questions about eating habits) Participants will have visits on 6 consecutive days. Over that time, they will wear 2 devices to monitor blood sugar and activity (even while at home). Participants will have 5 after-school visits. These include: - Health check - Snack plus food for the next 24 hours - Activity monitored - 3-hour sitting tests. Participants will do non-active things. Some will have 3-minute walks every 30 minutes. - Cognitive tests and questions about mood and anxiety are given on days #1 & 5. Participants will fast before the last visit in the morning. They will have: - 9 blood draws by IV catheter. Participants will drink sugar water. - Sitting test - Activity monitored - Meal (food buffet)