Acute Non-cardioembolic Ischemic Stroke Clinical Trial
— OCEANIC-STROKEOfficial title:
A Multicenter, International, Randomized, Placebo Controlled, Double-blind, Parallel Group and Event Driven Phase 3 Study of the Oral FXIa Inhibitor Asundexian (BAY 2433334) for the Prevention of Ischemic Stroke in Male and Female Participants Aged 18 Years and Older After an Acute Non-cardioembolic Ischemic Stroke or High-risk TIA
Researchers are looking for a better way to prevent an ischemic stroke which occurs when a blood clot travelled to the brain in people who within the last 72 hours had: - an acute stroke due to a blood clot that formed outside the heart (acute non-cardioembolic ischemic stroke), or - TIA/mini-stroke with a high risk of turning into a stroke (high-risk transient ischemic attack), and who are planned to receive standard of care therapy. Acute ischemic strokes or TIA/mini-stroke result from a blocked or reduced blood flow to a part of the brain. They are caused by blood clots that travel to the brain and block the vessels that supply it. If these blood clots form elsewhere than in the heart, the stroke is called non-cardioembolic. People who already had a non-cardioembolic stroke are more likely to have another stroke. This is why they are treated preventively with an antiplatelet therapy, the current standard of care. Antiplatelet medicines prevent platelets, components of blood clotting, from clumping together. Anticoagulants are another type of medicine that prevents blood clots from forming by interfering with a process known as coagulation (or blood clotting). The study treatment asundexian is a new type of anticoagulant currently under development to provide further treatment options. Asundexian aims to further improve the standard of care without increasing the risk of bleeding. The main purpose of this study is to learn whether asundexian works better than placebo at reducing ischemic strokes in participants who recently had a non-cardioembolic ischemic stroke or TIA/mini-stroke when given in addition to standard antiplatelet therapy. A placebo is a treatment that looks like a medicine but does not have any medicine in it. Another aim is to compare the occurrence of major bleeding events during the study between the asundexian and the placebo group. Major bleedings have a serious or even life-threatening impact on a person's health. Dependent on the treatment group, the participants will either take asundexian or placebo once a day for at least 3 months up to 31 months. Approximately every 3 months during the treatment period, either a phone call or a visit to the study site is scheduled on an alternating basis. In addition, one visit before and up to two visits after the treatment period are planned. During the study, the study team will: - Check vital signs such as blood pressure and heart rate - Examine the participants' heart health using an electrocardiogram (ECG) - Take blood samples - Ask the participants questions about how they are feeling and what adverse events they are having. An adverse event is any medical problem that a participant has during a study. Doctors keep track of all adverse events that happen in studies, even if they do not think the adverse events might be related to the study treatments. In addition, the participants will be asked to complete a questionnaire on quality of life at certain time points during the study.
| Status | Recruiting |
| Enrollment | 12300 |
| Est. completion date | October 10, 2025 |
| Est. primary completion date | October 10, 2025 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility | Inclusion Criteria: - Participants must be = 18 years of age - Acute non-cardioembolic stroke or high-risk TIA - Systemic or cerebrovascular atherosclerosis or acute non-lacunar infarct Exclusion Criteria: - Ischemic stroke = 7 days before the index event - Index stroke following procedures or strokes due to other rare causes - History of atrial fibrillation/flutter, left ventricular thrombus, mechanic valve or other cardioembolic source of stroke requiring anticoagulation |
| Country | Name | City | State |
|---|---|---|---|
| Argentina | Clinica IMA | Adrogue | Buenos Aires |
| Argentina | Centro Estudios Médicos e Invest. Clínicas "Dr. N. Quirno" | Buenos Aires | |
| Argentina | Complejo Medico Policial Churruca Visca | Neurology department | Buenos Aires | Ciudad Auton. De Buenos Aires |
| Argentina | Fleni | Sede Belgrano - Neurology Department | Buenos Aires | Ciudad Auton. De Buenos Aires |
| Argentina | Galeno | Sanatorio de la Trinidad Mitre - Neurology Department | Buenos Aires | Ciudad Auton. De Buenos Aires |
| Argentina | Hospital Italiano Buenos Aires | Buenos Aires | Ciudad Auton. De Buenos Aires |
| Argentina | Hospital General de Agudos JM Ramos Mejia | Neurologia Vascular - Enfermedades Cerebrovasculares | Buenos Aires (Capital Federal) | Buenos Aires |
| Argentina | Hospital General de Agudos Dr. Ignacio Pirovano | Capital Federal | Buenos Aires |
| Argentina | Sanatorio Allende | Departamento de Investigación Clínica | Córdoba | |
| Argentina | Hospital Italiano de La Plata | Clinical Research Department | La Plata | Buenos Aires |
| Argentina | Policlinico Lomas | Neurology Department | Lomas de Zamora | Buenos Aires |
| Argentina | Hospital Privado de Comunidad | Clinical Research Department | Mar del Plata | Buenos Aires |
| Argentina | Hospital Central de Mendoza | Mendoza | |
| Argentina | Grupo Gamma | Hospital Privado de Rosario, Neurology Department | Rosario | Santa Fe |
| Argentina | Sanatorio Parque | Departamento de Neurologia | Rosario | Santa Fe |
| Argentina | San Bernardo Hospital | Neurology Department | Salta | |
| Argentina | Hospital Interzonal General de Agudos Eva Perón | San Martín | Buenos Aires |
| Australia | Royal Adelaide Hospital | Adelaide | South Australia |
| Australia | Grampians Health Ballarat | Ballarat | Victoria |
| Australia | Sunshine Coast University Hospital | Birtinya | Queensland |
| Australia | Blacktown Hospital | Blacktownn | New South Wales |
| Australia | Eastern Health Box Hill Hospital | Box Hill | Victoria |
| Australia | Royal Brisbane and Women's Hospital | Brisbane | Queensland |
| Australia | Royal Prince Alfred Hospital | Camperdown | New South Wales |
| Australia | Monash Medical Centre | Clayton | Victoria |
| Australia | Lyell McEwin Hospital | Elizabeth Vale | South Australia |
| Australia | South Western Sydney Local Health District | Liverpool Hospital - Stroke and Neurovascular Department | Liverpool | New South Wales |
| Australia | Fiona Stanley Hospital | Murdoch | Western Australia |
| Australia | Sir Charles Gairdner Hospital | Nedlands | Western Australia |
| Australia | John Hunter Hospital | New Lambton Heights | New South Wales |
| Australia | Royal Melbourne Hospital | Parkville | Victoria |
| Australia | The Alfred Hospital | Prahran | Victoria |
| Australia | Prince of Wales Hospital NSW | Randwick | New South Wales |
| Australia | Redcliffe District Hospital | Redcliffe | Queensland |
| Australia | Gold Coast University Hospital | Southport | Queensland |
| Australia | Western Health Neuroscience Research Unit | St Albans | Victoria |
| Australia | Royal North Shore Hospital | St Leonards | New South Wales |
| Australia | Nepean Hospital | Sydney | New South Wales |
| Australia | Westmead Hospital | Westmead | New South Wales |
| Australia | Princess Alexandra Hospital Australia | Woollongabba | Queensland |
| Austria | LKH Feldkirch / Neurologie | Feldkirch | Vorarlberg |
| Austria | Universitaetsklinikum Graz | Abteilung für Neurologie | Graz | Steiermark |
| Austria | Medizinische Universität Innsbruck | Innsbruck | Tirol |
| Austria | Barmherzige Brueder Linz | Neurologie | Linz | Oberösterreich |
| Austria | Med Campus III | Klinik fuer Neurologie 2 | Linz | Oberösterreich |
| Austria | Landesklinikum Moedling | Abteilung für Neurologie | Moedling | Niederösterreich |
| Austria | Kardinal Schwarzenberg Klinikum | Schwarzach im Pongau | Salzburg |
| Austria | Universitätsklinikum St. Pölten | St. Pölten | Niederösterreich |
| Austria | AKH Wien | Univ. Klinik fuer Neurologie | Wien | |
| Austria | Barmherzige Brueder Wien | Abt. fuer Neurologie | Wien | |
| Austria | Klinik Floridsdorf | Abt. f. Neurologie | Wien | |
| Austria | Klinik Ottakring | Neurologische Abteilung | Wien | |
| Belgium | AZ Sint-Jan Brugge | Neurology | Brugge | |
| Belgium | UZ Brussel | Brussel | |
| Belgium | CU Saint-Luc/UZ St-Luc | Bruxelles - Brussel | |
| Belgium | Hôpital Erasme/Erasmus Ziekenhuis | Bruxelles - Brussel | |
| Belgium | UZ Gent | Gent | |
| Belgium | Jessa Hospital | Neurology Department | Hasselt | Limburg |
| Belgium | AZ Groeninge Campus Kennedylaan - Neurology department | Kortrijk | |
| Belgium | UZ Leuven - Neurology department | Leuven | |
| Belgium | CHC MontLégia Neurology Department | Liege | Liège |
| Belgium | Kust, Ommeland en Meetjesland (KOM) Network | AZ Damiaan - Neurology Department | Ostend | |
| Belgium | Vitaz | Sint-Niklaas Hospital - Cardiology Department | Sint-Niklaas | |
| Belgium | Clinique de l'Europe | Uccle | |
| Brazil | Hospital da Universidade Federal de Minas Gerais | Belo Horizonte | Minas Gerais |
| Brazil | Hospital Madre Tereza | Belo Horizonte | Minas Gerais |
| Brazil | Hospital das Clínicas de Botucatu - UNESP Botucatu | Botucatu | Sao Paulo |
| Brazil | Hospital Brasilia | Brasilia | Distrito Federal |
| Brazil | Hospital Universitário UFMS | Campo Grande | Mato Grosso Do Sul |
| Brazil | Hospital das Clinicas da Universidade Federal do Paraná | Curitiba | Parana |
| Brazil | Hospital Estadual Central Vitoria - Fundação INOVA - ES | Espirito Santo | Espírito Santo |
| Brazil | Hospital Geral de Fortaleza | Fortaleza | Ceará |
| Brazil | Clinica Neurologica e Neurocirurgica de Joinville Ltda | Joinville | Santa Catarina |
| Brazil | Sociedade Matonense de Benemerência | Matão | Sao Paulo |
| Brazil | Hospital de Clinicas de Porto Alegre | Clinical Research Center - Surgery Research Center | Porto Alegre | Rio Grande Do Sul |
| Brazil | Hospital Moinhos de Vento-Centro Clínico | Porto Alegre | Rio Grande Do Sul |
| Brazil | Hosp Clínicas Facult. Med. de Ribeirão Preto / USP | Ribeirão Preto/SP | Sao Paulo |
| Brazil | Hospital Pró-Cardíaco | Rio de Janeiro | |
| Brazil | Hospital Sao Lucas Copacabana | Clinical Research Department | Rio de Janeiro | |
| Brazil | L'Dor - Instituto de Ensino e Pesquisa | Rio de Janeiro | |
| Brazil | Centro de Pesquisas do Hospital Bahia | Salvador | Bahia |
| Brazil | Hospital Universitario Professor Edgard Santos | Salvador | Bahia |
| Brazil | Fundação Facu. Reg de Medicina de São José do Rio Preto | São José do Rio Preto | Sao Paulo |
| Brazil | Science Valley Research Institute | Sao Paulo | |
| Brazil | Hospital Nove de Julho | São Paulo | Sao Paulo |
| Brazil | Unifesp/Epm | São Paulo | Sao Paulo |
| Bulgaria | Multispecialty Hospital for Active Treatment St. Ivan Rilski - 2003 | Neurological Department | Dupnitsa | |
| Bulgaria | MHAT Haskovo AD | Department of Nervous Diseases | Haskovo | |
| Bulgaria | Multiprofile Hospital for Active Treatment Pazardzhik | Pazardzhik | |
| Bulgaria | Military Medical Academy | Multiprofile Hospital for Active Treatment Pleven - Neurology Department | Pleven | |
| Bulgaria | UMHAT Dr Georgi Stranski Pleven | Department of Neurology | Pleven | |
| Bulgaria | Multiprofile Hospital for Active Treatment | St. Panteleimon Hospital - Neurology Department | Plovdiv | |
| Bulgaria | University Multiprofile Hospital for Active Treatment Pulmed | Neurology Department | Plovdiv | |
| Bulgaria | University Multispecialty Hosp Dep General&Vascu Neurology | Ruse | |
| Bulgaria | Acibadem City Clinic | Tokuda Hospital - Department of Neurology and Sleep Medicine | Sofia | |
| Bulgaria | Military Medical Academy | Multiprofile Hospital for Active Treatment Sofia - Clinic of Neurological Diseases | Sofia | |
| Bulgaria | Multiprofile Hospital for Active Treatment National Cardiology Hospital | Clinic for Neurological Diseases | Sofia | |
| Bulgaria | Multiprofile Hospital for Active Treatment Neurology and Psychiatry St. Naum | Intensive Treatment of Nervous System Disorders | Sofia | |
| Bulgaria | Second Multi-profile Hospital for Active Treatment - Sofia | Clinic of Neurology | Sofia | |
| Bulgaria | University Hospital for Active Treatment St. Anna | Neurology Department | Sofia | |
| Bulgaria | University Hospital for Active Treatment Tsaritsa Joanna - ISUL | Neurology Department | Sofia | |
| Bulgaria | University Multi-profile Hospital for Active Treatment and Emergency Medicine Pirogov | Department of Nervous Diseases | Sofia | |
| Bulgaria | University Multiprofile Hospital for Active Treatment Sofiamed | Neurology Department | Sofia | |
| Bulgaria | MHAT Sveta Marina EAD | Varna | |
| Canada | University of Calgary | Foothills Medical Centre - Department of Clinical Neurosciences - Stroke Clinical Trials Group | Calgary | Alberta |
| Canada | CIUSSS Saguenay Lac-St-Jean | Chicoutimi | Quebec |
| Canada | University of Alberta Hospital | Edmonton | Alberta |
| Canada | Queen Elizabeth II Complex | Halifax | Nova Scotia |
| Canada | Hamilton General Hospital | Hamilton | Ontario |
| Canada | Kelowna General Hospital | Kelowna | British Columbia |
| Canada | Kingston Health Sciences Centre (KGH Site) | Kingston | Ontario |
| Canada | Center For Neurologic Research | Lethbridge | |
| Canada | London Health Sciences Centre | London | Ontario |
| Canada | CHUM - Centre hospitalier de l'Université de Montréal | Montreal | Quebec |
| Canada | Jewish General Hospital | Montreal | Quebec |
| Canada | McGill University | Montreal | Quebec |
| Canada | Royal Columbian Hospital | New Westminster | British Columbia |
| Canada | The Ottawa Hospital | The Ottawa Hospital Research Institute - Neurology - Ottawa Stroke Program | Ottawa | Ontario |
| Canada | CHU de Québec-Hôpital de l'Enfant-Jésus | Quebec | |
| Canada | University of Saskatchewan, Royal University Hospital | Saskatoon | Saskatchewan |
| Canada | CIUSSS de l'Estrie-CHUS, Hopital Fleurimont | Sherbrooke | Quebec |
| Canada | Health Sciences North Research Institute | Sudbury, Canada | Sudbury | Ontario |
| Canada | Sunnybrook Health Sciences Centre | Toronto | Ontario |
| Canada | Unity Health Toronto | St. Michael's Hospital - Stroke Research | Toronto | Ontario |
| Canada | Vancouver General Hospital / Vancouver Stroke Program | Vancouver | British Columbia |
| Canada | Winnepeg Health Sciences Centre | Winnipeg | Manitoba |
| China | Baoji Central Hospital | Baoji | Shaanxi |
| China | Baogang hospital | Baotou | Inner Mongolia |
| China | The First Affiliated Hospital of Baotou Medical College | Baotou | Inner Mongolia |
| China | Beijing Tsinghua Changgung Hospital | Beijing | |
| China | Xuanwu Hospital Capital Medical University | Beijing | |
| China | Cangzhou Central Hospital | Cangzhou | Hebei |
| China | The First Hospital of Jilin University | Changchun | Jilin |
| China | The Third Xiangya Hospital of Central South University | Changsha | Hunan |
| China | Daqing Oilfield General Hospital | Daqing | Heilongjiang |
| China | Daqing People's Hospital | Daqing | Heilongjiang |
| China | People's Hospital of Deyang City | Deyang | Sichuan |
| China | Foshan First People's Hospital | Foshan | Guangdong |
| China | Guangdong Provincial People's Hospital | Guangzhou | Guangdong |
| China | Guangzhou Overseas Chinese Hospital | Guangzhou | Guangdong |
| China | Zhujiang Hospital of Southern Medical University | Guangzhou | Guangdong |
| China | Hainan General Hospital | Haikou | Hainan |
| China | Sir Run Run Shaw Hospital, Zhejiang Univ. School of Medicine | Hangzhou | Zhejiang |
| China | Hengshui Harrison International Peace Hospital | Hengshui | Hebei |
| China | 1st Affiliated Hospital of Nanhua University | Hengyang | Hunan |
| China | The Affiliated Huaian No.1 People's Hospi of NJ Medical Unv. | Huai'an | Jiangsu |
| China | Affiliated Hospital of Jiangsu University | JiangSu | Jiangsu |
| China | Qilu Hosp., Shandong Univ. | Jinan | Shandong |
| China | Affiliated Hospital of Jining Medical University | Jining | Shandong |
| China | Jining No.1 people's Hospital | Jining | Shandong |
| China | The First Affiliated Hospital of Jinzhou Medical University | Jinzhou | Liaoning |
| China | Lanzhou University Second Hospital | Lanzhou | Gansu |
| China | Liaocheng People's Hospital | Liaocheng | Shandong |
| China | Linyi People's Hospital | Linyi | Shandong |
| China | People's Hospital of Liuzhou City | Liuzhou | Guangxi |
| China | 1st Affiliated Hospital of Henan Science and Technology Univ | Luoyang | Henan |
| China | Luoyang Third People's Hospital | Luoyang | Henan |
| China | Jiangxi Provincial People's Hospital | Nanchang | Jiangxi |
| China | The First Affiliated Hospital of NanChang University | Nanchang | Jiangxi |
| China | Nanjing First Hospital | Nanjing | Jiangsu |
| China | The Second Affiliated Hospital of Nanjing Medical university | Nanjing | Jiangsu |
| China | Zhongda Hospital Southeast University | Nanjing | Jiangsu |
| China | Hwa Mei Hospital, University of Chinese Academy Sciences | Ningbo | Zhejiang |
| China | Huashan Hospital, Fudan University | Shanghai | |
| China | Yangpu Hospital, Tongji University | Shanghai | |
| China | General Hospital of Northern Theater Command | Shenyang | Liaoning |
| China | The Third Hospital of Hebei Medical University | Shijiazhuang | Hebei |
| China | Taian City Central Hospital | Taian | Shandong |
| China | Taizhou Hospital of Zhejiang Province | Taizhou | Zhejiang |
| China | Tangshan people's Hospital | Tangshan | Hebei |
| China | Tianjin Huanhu Hospital | Tianjin | |
| China | Tianjin People's Hospital | Tianjin | |
| China | The Central Hospital of Wuhan, Tongji Medl Collg Huazhong... | Wuhan | Hubei |
| China | Wuhan No. 4 Hospital | Wuhan | Hubei |
| China | Wuxi No.2 People's Hospital | Wuxi | Jiangsu |
| China | Wuxi People's Hospital | Wuxi | Jiangsu |
| China | Shaanxi Provincial People's Hospital | Xi'an | Shanxi |
| China | Yan'an University Xianyang Hospital | Xianyang | Shaanxi |
| China | Qinghai University Affiliated Hospital | Xining | Qinghai |
| China | The Third Affiliated Hospital of Xinxiang Medical university | Xinxiang | Henan |
| China | Xinxiang Central Hospital | Xinxiang | Henan |
| China | Xuancheng People's Hospital | Xuancheng | Anhui |
| China | Xuzhou Central Hospital | Xuzhou | Jiangsu |
| China | Affiliated Hospital of Yangzhou University | Yangzhou | Jiangsu |
| China | General Hospital of Ningxia Medical University | Yinchuan | Ningxia |
| Colombia | Fundación Cardiomet CEQUIN Eje Cafetero | Armenia | Quindío |
| Colombia | Clínica de la Costa SAS | Baranquilla | Atlántico |
| Colombia | Hospital Universitario Mayor-MÉDERI | Bogota | Distrito Capital De Bogotá |
| Colombia | Clínica Imbanaco S.A.S | Cali | Valle Del Cauca |
| Colombia | Fundación Valle de Lili | Cali | |
| Colombia | Clínica Universidad de la sabana | Chia | Cundinamarca |
| Colombia | Fundación Cardiovascular de Colombia | Floridablanca | |
| Colombia | Clinica Cardio VID | Medellin | |
| Colombia | Hospital Alma Mater de Antioquia | Medellin | Antioquia |
| Colombia | Hospital General de Medellin | Medellin | Antioquia |
| Colombia | Hospital San Vicente Fundación | Medellin | |
| Colombia | Promotora Médica Las Américas S.A.- Clinica Las Americas | Medellin | Antioquia |
| Colombia | Clínica Medellín | Medellín | |
| Colombia | Sociedad Médica Rionegro SOMER S.A. | Rionegro | Antioquia |
| Colombia | Fundación Hospital Universidad del Norte | Soledad | Atlántico |
| Czechia | Fakultni nemocnice u sv. Anny - I.neurologicka klinika | Brno | |
| Czechia | Nemocnice Ceske Budejovice, a.s. - Department of neurology | Ceské Budejovice | |
| Czechia | Nemocnice Chomutov, o.z. | Chomutov | |
| Czechia | Nemocnice Jihlava - Neurologicke oddeleni | Jihlava | |
| Czechia | Karvinska hornicka nemocnice a.s. - Neurologicke oddeleni | Karvina | |
| Czechia | Krajska nemocnice Liberec - neurologicke oddeleni | Liberec | |
| Czechia | Fakultni nemocnice Ostrava - Neurologicka klinika | Ostrava - Poruba | |
| Czechia | Nemocnice AGEL Ostrava-Vítkovice - Neurologicke oddeleni | Ostrava - Vitkovice | |
| Czechia | Nemocnice Pardubickeho Kraje, as - Neurologická klinika | Pardubice | |
| Czechia | Fakultni nemocnice Kralovske Vinohrady - Neurologicka klinika | Praha | |
| Czechia | Fakultni Thomayerova Nemocnice - neurology department | Praha 4 | |
| Czechia | Nemocnice na Homolce - Neurology Department | Praha 5-Motol | |
| Czechia | Ustredni vojenska nemocnice Praha | Praha 6 | |
| Czechia | Masaryk Hospital Usti n/L - neurology department | Ústí nad Labem | |
| Czechia | Krajská nemocnice T. Bati, a.s. - Neurologické oddelení | Zlín | |
| Denmark | Aalborg Universitetshospital -Neurology | Aalborg | |
| Denmark | Aarhus Universitetshospital, Neurologisk Afdeling | Aarhus N | |
| Denmark | Glostrup RH, Neurologisk Afdeling | Glostrup | |
| Denmark | Herlev Hospital - Neurology Dept. | Herlev | |
| Denmark | Regionshospitalet Gødstrup, Neurologisk Afd. | Herning | |
| Denmark | Bispebjerg Hospital, Neurologisk Afdeling | København NV | |
| Denmark | Kolding Sygehus, Neurologisk Afdeling | Kolding | |
| Denmark | Odense Universitetshospital, Dept of Neurology | Odense C | |
| Finland | HUS, Meilahden sairaala | Helsinki | |
| Finland | Pohjois-Karjalan sairaanhoitopiiri | Joensuu | |
| Finland | Kuopion yliopistollinen sairaala | Kuopio | |
| Finland | Tampereen yliopistollinen sairaala, keskussairaala | Tampere | |
| Finland | Turun yliopistollinen keskussairaala | Turku | |
| France | Hopital Jean Minjoz | Besancon | |
| France | Hôpital Pellegrin - Bordeaux | Bordeaux | |
| France | CH Boulogne-Sur-Mer - Neurologie | Boulogne-sur-mer | |
| France | Hôpital La Cavale Blanche - CHU de Brest | Brest Cedex | |
| France | CH Sud Francilien, Neurologie | Corbeil-essonnes | |
| France | CHU Dijon, Neurologie | DIJON Cedex | |
| France | Raymond-Poincare neurologie, Garches | Garches | |
| France | Centre Hospitalier Universitaire - Le Kremlin Bicêtre | Le Kremlin-bicetre | |
| France | Centre Hospitalier - Le Mans | Le Mans | |
| France | Hôpital B - Lille | Lille | |
| France | Hopital Saint Philibert - Service de Neurologie | LOMME cedex | |
| France | Hôpital Wertheimer - Lyon | Lyon | |
| France | La Timone, Neurologie, MARSEILLE | Marseille | |
| France | Hopital Central - Nancy | Nancy | |
| France | Hôpital Guillaume et René Laennec - Nantes | Nantes | |
| France | Hôpital Pasteur - Nice | Nice | |
| France | Hopital Carémeau - Nîmes | Nîmes | |
| France | Centre hospitalier Sainte Anne | Paris | |
| France | Hopital Bichat, Service de Neurologie, Paris | Paris | |
| France | Hôpital de la Pitié-Salpétrière | Paris | |
| France | Hôpital Lariboisière - Paris | Paris | |
| France | Hôpital Rothschild - Paris | Paris | |
| France | H Maison Blanche, Neurologie, REIMS | Reims | |
| France | Hôpital Pontchaillou | Rennes Cedex | |
| France | CHU STRASBOURG - Hôpital de Hautepierre | Strasbourg | |
| France | Hopital Foch, Neurologie, SURESNES | SURESNES Cedex | |
| France | Hopital des Armees Sainte-Anne, Neurologie, Toulon | Toulon cedex 09 | |
| France | Hôpital Purpan - Toulouse | Toulouse | |
| France | H bretonneau, neurologie, Tours | TOURS cedex 9 | |
| Germany | UniKlinikum Aachen/Neurologie | Aachen | Nordrhein-Westfalen |
| Germany | Klinikum Altenburger Land / Studienzentrum Neurologie | Altenburg | Thüringen |
| Germany | Rhön-Klinikum Campus Bad Neustadt/Neurologie | Bad Neustadt | Bayern |
| Germany | Vivantes Klinikum Neukölln / Neurologie mit Stroke Unit | Berlin | |
| Germany | Uniklinik Bonn / Neurologie | Bonn | Nordrhein-Westfalen |
| Germany | Städtisches Klinikum Dresden / Neurologie | Dresden | Sachsen |
| Germany | Universitätsklinikum Dresden/Neurologie | Dresden | Sachsen |
| Germany | Marien Hospital Düsseldorf / Neurologie | Düsseldorf | Nordrhein-Westfalen |
| Germany | Universitätsklinikum Düsseldorf / Neurologie | Düsseldorf | Nordrhein-Westfalen |
| Germany | Universitätsklinikum Erlangen/Neurologie | Erlangen | Bayern |
| Germany | Alfried Krupp Krankenhaus Rüttenscheid /Neurologie | Essen | Nordrhein-Westfalen |
| Germany | Universitätsklinikum Frankfurt / Neurologie | Frankfurt | Hessen |
| Germany | Universitätsklinikum Freiburg / Neurologie | Freiburg | Baden-Württemberg |
| Germany | SRH Wald-Klinikum Gera gGmbH | Gera | Thüringen |
| Germany | Universität Gießen-Marburg, Standort Gießen/Neurologie | Gießen | Hessen |
| Germany | Universitätsmedizin Göttingen/ Neurologie | Göttingen | Niedersachsen |
| Germany | Universitätsmedizin Greifswald/Neurologie | Greifswald | Mecklenburg-Vorpommern |
| Germany | Universitätsklinikum Halle (Saale)/Neurologie | Halle | Sachsen-Anhalt |
| Germany | Asklepios Klinik Altona Hamburg / Neurologie | Hamburg | |
| Germany | Asklepios Klinik Barmbek/ Neurologie | Hamburg | |
| Germany | Asklepios Klinik Wandsbek/Neurologie | Hamburg | |
| Germany | Medizinische Hochschule Hannover/Neurologie | Hannover | Niedersachsen |
| Germany | Universitaetsklinikum Heidelberg / Neurologie | Heidelberg | Baden-Württemberg |
| Germany | Uniklinik Jena/ Neurologie | Jena | Thüringen |
| Germany | Universitätsklinik Leipzig /Neurologie | Leipzig | Sachsen |
| Germany | Johannes Gutenberg-Universität Mainz - Neurologie | Mainz | Rheinland-Pfalz |
| Germany | Universitätsklinikum Mannheim / Neurologie | Mannheim | Baden-Württemberg |
| Germany | Kreisklinikum Siegen / Neurologie | Siegen | Nordrhein-Westfalen |
| Germany | GFO KlinikTroisdorf/Neurologie | Troisdorf | Nordrhein-Westfalen |
| Germany | Universitätsklinikum Ulm/Neurologische Klinik | Ulm | Baden-Württemberg |
| Greece | University General Hospital of Alexandroupolis | Alexandroupoli | |
| Greece | 401 General Military Hospital of Athens | Athens | |
| Greece | AIGINITEION Hospital | Athens | |
| Greece | Athens Naval Hospital | Athens | |
| Greece | G. GENNIMATAS General State Hospital of Athens | Athens | |
| Greece | General Hosp of Athens "Korgialenio-Benakeio" RCH | Athens | |
| Greece | General Hospital of Athens "Evangelismos" | Athens | |
| Greece | University General Hospital ATTIKON | Chaidari | |
| Greece | University General Hospital of Heraklion | Heraklion | |
| Greece | Ioannina University General Hospital | Ioannina | |
| Greece | University General Hospital of Larissa | Larissa | |
| Greece | Metropolitan Hospital | Neo Faliro Piraeus | |
| Greece | University General Hospital of Patra | Patra | |
| Greece | PAPANIKOLAOU General Hospital Thessaloniki | Pilea Chortiatis Thessaloniki | |
| Greece | AHEPA University General Hospital of Thessaloniki | Thessaloniki | |
| Greece | General Hospital of Thessaloniki Papageorgiou | Thessaloniki | |
| Hungary | Bajai Szent Rokus Korhaz | Baja | |
| Hungary | Budapesti Bajcsy-Zsilinszky Korhaz es Rendelointezet | Budapest | |
| Hungary | Budapesti Jahn Ferenc Del-pesti Korhaz es Rendelointezet | Budapest | |
| Hungary | Eszak-Pesti Centrumkorhaz-Honvedkorhaz | Budapest | |
| Hungary | Semmelweis Egyetem Idegsebeszeti es Neurointervencios Klinika | Budapest | |
| Hungary | Semmelweis Egyetem, Altalanos Orvostudomanyi Kar, Neurologiai Klinika | Budapest | |
| Hungary | Debreceni Egyetem Klinikai Kozpont Neurologiai Klinika | Debrecen | |
| Hungary | Petz Aladar Megyei Korhaz | Gyor | |
| Hungary | Kistarcsai Flor Ferenc Korhaz | Kistarcsa | |
| Hungary | Szent Damjan Gorogkatolikus Korhaz | Kisvarda | |
| Hungary | Nagykanizsai Kanizsai Dorottya Korhaz | Nagykanizsa | |
| Hungary | Szabolcs-Szatmar-Bereg Varmegyei Oktatokorhaz | Nyiregyhaza | |
| Hungary | Pecsi Tudomanyegyetem Klinikai Kozpont | Pecs | |
| Hungary | Soproni Erzsebet Oktato Korhaz es Rehabilitacios Intezet | Sopron | |
| Hungary | Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Orvostudomanyi Kar Szent-Gyorgyi Albert Klinikai Kozpont Neurologiai Klinika | Szeged | |
| Hungary | Zala Varmegyei Szent Rafael Korhaz | Zalaegerszeg | |
| India | Zydus Hospital | Ahmedabad | |
| India | National Institute of Mental Health and Neurosciences (NIMHANS) | Bangalore | |
| India | Post Graduate Institute of Medical Education and Research | Chandigarh | |
| India | K.G. Hospital | Coimbatore | |
| India | Government General Hospital, Guntur | Guntur | |
| India | Lalitha Super Specialities Hospital | Guntur | |
| India | Artemis Hospitals | Gurgaon | |
| India | Guwahati Neurological Research Centre | Guwahati | |
| India | Omega Hospitals, Hyderabad | Hyderabad | |
| India | Yashoda Hospital | Hyderabad | |
| India | Sawami Man Singh (SMS) Medical College & Attached Hospitals | Jaipur | |
| India | Shree Krishna Hospital | Karamsad | |
| India | Bangur Institute of Neurology | Kolkata | |
| India | Aster MIMS Hospital, Kozhikode | Kozhikode | |
| India | Christian Medical College & Hospital (CMCH) - Ludhiana | Ludhiana | |
| India | Ganga CARE Hospital Ltd. | Nagpur | |
| India | All India Institute of Medical Sciences (AIIMS) - New Delhi | New Delhi | |
| India | Bharti Hospital | Pune | |
| India | Government Medical College - Thiruvanathapuram | Thiruvananthapuram | |
| India | Sree Chitra Tirunal Institute for Medical Sciences and Technology | Thiruvananthapuram | |
| India | Christian Medical College & Hospital (CMCH) - Vellore | Vellore | |
| Israel | Assuta Ashdod | Ashdod | |
| Israel | Barzilai Medical Center | Neurology Department | Ashkelon | |
| Israel | Clalit Health | Soroka Medical Center - Internal Medicine Department | Beer Sheva | |
| Israel | Hillel Yaffe Medical Center | Hadera | |
| Israel | Lady Davis Carmel Medical Center | Haifa | |
| Israel | Rambam Health Corporation | Haifa | |
| Israel | Edith Wolfson Medical Center | Internal Medicine Department | Holon | |
| Israel | Hadassah Hebrew University Hospital Ein Kerem | Jerusalem | |
| Israel | Shaare Zedek Medical Center | Jerusalem | |
| Israel | Meir Medical Center | Kfar Saba | |
| Israel | Rabin Medical Center | Beilinson Hospital - Internal Medicine C Department | Petach Tikva | |
| Israel | Tel-Aviv Sourasky Medical Center | Tel Aviv | |
| Israel | Chaim Sheba Medical Center | Tel Hashomer | |
| Israel | Health Corporation of the Ziv Medical Center (R.A.) | Zefat | |
| Israel | Shamir Medical Center (Assaf Harofeh) | Zerifin | |
| Italy | A.O.U. Ospedali Riuniti di Ancona | Ancona | |
| Italy | ASST Papa Giovanni XXIII | Bergamo | Lombardia |
| Italy | AUSL di Bologna | Bologna | Emilia-Romagna |
| Italy | A.O.U. Careggi | Firenze | Toscana |
| Italy | AUSL della Romagna | Forlì Cesena | Emilia-Romagna |
| Italy | ASL1 Avezzano-Sulmona-L'Aquila - Abruzzo | L'Aquila | Abruzzo |
| Italy | ASL Lecce | Lecce | Puglia |
| Italy | A.O.U. Policlinico G. Martino | Messina | Sicilia |
| Italy | Ospedale San Raffaele s.r.l. | Milano | Lombardia |
| Italy | A.O.R.N. Antonio Cardarelli | Napoli | Campania |
| Italy | A.O. Ospedali Riuniti Villa Sofia-Cervello | Palermo | Sicilia |
| Italy | A.O.U. di Parma | Parma | Emilia-Romagna |
| Italy | A.O. di Perugia | Perugia | Umbria |
| Italy | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Roma | Lazio |
| Italy | Fondazione PTV Policlinico Tor Vergata | Roma | Lazio |
| Italy | A.O.U. San Giovanni di Dio Ruggi d'Aragona | Salerno | Campania |
| Italy | ASL 2 Savonese | Savona | Liguria |
| Italy | A.O.U. Senese | Siena | Toscana |
| Italy | Ospedale San Giovanni Bosco - ASL Città di Torino | Torino | |
| Italy | A.O.U. Santa Maria Misericordia UD | Udine | Friuli-Venezia Giulia |
| Italy | A.O.U.I. Verona | Verona | Veneto |
| Italy | IRCCS Ospedale Sacro Cuore Don Calabria | Verona | Veneto |
| Italy | ULSS8 Berica | Vicenza | Veneto |
| Japan | Ohnishi Neurological Center | Akashi | Hyogo |
| Japan | Mazda Motor Corporation Mazda Hospital | Aki-gun | Hiroshima |
| Japan | Japanese Red Cross Asahikawa Hospital | Asahikawa | Hokkaido |
| Japan | National Hospital Organization Beppu Medical Center | Beppu | Oita |
| Japan | Nozaki Tokushukai Hospital | Daito | Osaka |
| Japan | Fukuoka Neurosurgical Hospital | Fukuoka | |
| Japan | Kyushu Central Hospital | Fukuoka | |
| Japan | National Hospital Organization Kyushu Medical Center | Fukuoka | |
| Japan | Saiseikai Fukuoka General Hospital | Fukuoka | |
| Japan | Social Medical Corporation the Chiyukai foundation Fukuoka Wajiro Hospital | Fukuoka | |
| Japan | Hakodate Shintoshi Hospital | Hakodate | Hokkaido |
| Japan | Hamamatsu Rosai Hospital | Hamamatsu | Shizuoka |
| Japan | Seirei Hamamatsu General Hospital | Hamamatsu | Shizuoka |
| Japan | Hiroshima General Hospital | Hatsukaichi | Hiroshima |
| Japan | Higashihiroshima Medical Center | Higashihiroshima | Hiroshima |
| Japan | Hyogo Brain and Heart Center | Himeji | Hyogo |
| Japan | Hiroshima City North Medical Center Asa Citizens Hospital | Hiroshima | |
| Japan | Atsuchi Neurosurgery Hospital | Kagoshima | |
| Japan | Kimitsu Chuo Hospital | Kisarazu | Chiba |
| Japan | Kokura Memorial Hospital | Kitakyushu | Fukuoka |
| Japan | Steel Memorial Yawata Hospital | Kitakyushu | Fukuoka |
| Japan | Eishokai Yoshida Hospital | Kobe | Hyogo |
| Japan | Japanese Red Cross Kochi Hospital | Kochi | |
| Japan | Yamanashi Prefectural Central Hospital | Kofu | Yamanashi |
| Japan | Southern Tohoku Medical Clinic | Koriyama | Fukushima |
| Japan | Kumamoto City Hospital | Kumamoto | |
| Japan | Ijinkai Takeda General Hospital | Kyoto | |
| Japan | Koseikai Takeda Hospital | Kyoto | |
| Japan | Maebashi Red Cross Hospital | Maebashi | Gunma |
| Japan | Japan Organization of Occupational Health and Safety Kagawa Rosai Hospital | Marugame | Kagawa |
| Japan | Mishuku Hospital | Meguro-ku | Tokyo |
| Japan | National Hospital Organization Tokyo Medical Center | Meguro-ku | Tokyo |
| Japan | Kyorin University Hospital | Mitaka | Tokyo |
| Japan | Nagano Municipal Hospital | Nagano | |
| Japan | Chubu Rosai Hospital | Nagoya | Aichi |
| Japan | Nagoya Ekisaikai Hospital | Nagoya | Aichi |
| Japan | Japan Culture and Welfare Federation of Agricultural Cooperatives | Hokushin General Hospital | Nakano | Nagano |
| Japan | Seisho Hospital | Odawara | Kanagawa |
| Japan | Oita Prefectural Hospital | Oita | |
| Japan | CMIC HealthCare Institute Co. Ltd. | Local IAA OCGMC - Okayama City Civic Hospital - Clinical Trial Centre | Okayama | |
| Japan | National Hospital Organization Osaka National Hospital | Osaka | |
| Japan | Osaka General Medical Center | Osaka | |
| Japan | Toho University Sakura Medical Center | Sakura | Chiba |
| Japan | Teine Keijinkai Hospital | Sapporo | Hokkaido |
| Japan | Kohnan Hospital | Sendai | Miyagi |
| Japan | Tosei General Hospital | Seto | Aichi |
| Japan | JCHO Shimonoseki Medical Center | Shimonoseki | Yamaguchi |
| Japan | Shizuoka City Shimizu Hospital | Shizuoka | |
| Japan | Shizuoka City Shizuoka Hospital | Shizuoka | |
| Japan | Osaka Saiseikai Senri Hospital | Suita | Osaka |
| Japan | Tokyo Metropolitan Bokutoh Hospital | Sumida-ku | Tokyo |
| Japan | Japanese Red Cross Society Suwa Hospital | Suwa | Nagano |
| Japan | National Hospital Organization Disaster Medical Center | Tachikawa | Tokyo |
| Japan | Kagawa Prefectural Central Hospital | Takamatsu | Kagawa |
| Japan | Takamatsu Red Cross Hospital | Takamatsu | Kagawa |
| Japan | Japanese Red Cross Takayama Hospital | Takayama | Gifu |
| Japan | Minamiwakayama Medical Center | Tanabe | Wakayama |
| Japan | JA Toride Medical Center | Toride | Ibaraki |
| Japan | Fujita Health University Hospital | Toyoake | Aichi |
| Japan | National Hospital Organization Toyohashi Medical Center | Toyohashi | Aichi |
| Japan | Tsuchiura Kyodo General Hospital | Tsuchiura | Ibaraki |
| Japan | National Hospital Organization Ureshino Medical Center | Ureshino | Saga |
| Japan | Wakayama Medical University Hospital | Wakayama | |
| Japan | National Hospital Organization Saitama National Hospital | Wako | Saitama |
| Japan | National Hospital Organization Yokohama Medical Center | Yokohama | Kanagawa |
| Japan | Saiseikai Yokohamashi Nanbu Hospital | Yokohama | Kanagawa |
| Kazakhstan | Multiprofile regional hospital | Aktobe | |
| Kazakhstan | City Clinical Hospital No7 - Stroke Unit | Almaty | |
| Kazakhstan | Multidisciplinary City Hospital No1 - Stroke Unit | Astana | |
| Kazakhstan | Turkestan Regional Clinical Hospital - Stroke Unit | Shymkent | |
| Korea, Republic of | Hallym University Sacred Heart Hospital | Anyang-si | Gyeonggido |
| Korea, Republic of | Dong-A University Hospital | Busan | |
| Korea, Republic of | Inje University Busan Paik Hospital | Busan | |
| Korea, Republic of | Chungbuk National University Hospital | Cheongju-si | Chungcheongbugdo |
| Korea, Republic of | Keimyung University Dongsan Medical Center | Daegu | |
| Korea, Republic of | Kyungpook National University Hospital | Daegu | Daegu Gwang''yeogsi |
| Korea, Republic of | Eulji University Hospital | Daejeon | |
| Korea, Republic of | Inje University Ilsan Paik Hospital | Goyang-si | Gyeonggido |
| Korea, Republic of | Chonnam National University Hospital | Gwangju | |
| Korea, Republic of | Inha University Hospital | Incheon | |
| Korea, Republic of | Seoul National University Bundang Hospital | Seongnam-si | Gyeonggido |
| Korea, Republic of | Asan Medical Center | Seoul | |
| Korea, Republic of | Korea University Anam Hospital | Seoul | |
| Korea, Republic of | Korea University Guro Hospital | Seoul | |
| Korea, Republic of | Kyung Hee University Medical Center | Seoul | Seoul Teugbyeolsi |
| Korea, Republic of | Samsung Medical Center | Seoul | |
| Korea, Republic of | Seoul National University Hospital | Seoul | Seoul Teugbyeolsi |
| Korea, Republic of | Severance Hospital, Yonsei University Health System | Seoul | |
| Korea, Republic of | SoonChunHyang University Seoul Hospital | Seoul | |
| Korea, Republic of | The Catholic University of Korea Seoul St. Mary's Hospital | Seoul | |
| Korea, Republic of | Nowon Eulji Medical Center, Eulji University | Seoul, | |
| Latvia | Jekabpils Regional Hospital | Jekabpils | |
| Latvia | Rezekne Hospital | Rezekne | |
| Latvia | P. Stradins Clinical University Hospital | Riga | |
| Latvia | Riga East Clinical University Hospital "Gailezers" | Riga | |
| Latvia | Vidzemes Hospital | Valmiera | |
| Lithuania | Alytus County S. Kudirka Hospital | Alytus | |
| Lithuania | Hospital of LT University of Health Sciences Kaunas Clinics | Kaunas | |
| Lithuania | LUHS Kauno Hospital (Josvainiu str.) | Kaunas | |
| Lithuania | Siauliai Republican hospital | Siauliai | |
| Lithuania | Republican Vilnius University Hospital | Vilnius | |
| Lithuania | Vilnius University Hospital Santaros Klinikos | Vilnius | |
| Malaysia | Hospital Raja Perempuan Zainab II | Kelantan | |
| Malaysia | Hospital Universiti Sains Malaysia | Kelantan | |
| Malaysia | Queen Elizabeth Hospital Malaysia | Kota Kinabalu | |
| Malaysia | Hospital Kuala Lumpur | Kuala Lumpur | |
| Malaysia | University Malaya Medical Centre | Kuala Lumpur | |
| Malaysia | Hospital Seberang Jaya | Pulau Pinang | |
| Malaysia | Sarawak General Hospital | Sarawak | |
| Malaysia | Hospital Sultan Abdul Aziz Shah | Selangor | |
| Malaysia | Hospital Sultanah Nur Zahirah Medical Department | Terengganu | |
| Netherlands | Academisch Medisch Centrum (AMC) | Amsterdam | |
| Netherlands | OLVG | Location West - Neurology Department | Amsterdam | |
| Netherlands | Jeroen Bosch Ziekenhuis | Den Bosch | |
| Netherlands | HagaZiekenhuis | Department of Neurology | Den Haag | |
| Netherlands | Catharina Hospital | Neurology Outpatient Clinic | Eindhoven | Noord-Brabant |
| Netherlands | Medisch Spectrum Twente | Enschede | |
| Netherlands | Zuyderland Medical Centre | Sittard-Geleen - Neurology Department | Heerlen | |
| Netherlands | St. Antonius Hospital | Nieuwegein - Neurology Department - Stroke Unit | Nieuwegein | |
| Netherlands | Maasstad Ziekenhuis | Neurology Department | Rotterdam | |
| Netherlands | University Medical Center (UMC) Utrecht | Neurology and Neurosurgery Department | Utrecht | |
| Netherlands | Isala Zwolle | Neurology Department | Zwolle | |
| Norway | Ålesund sykehus Nevrologisk poliklinikk | Ålesund | |
| Norway | Haukeland Universitetssykehus Nevrologisk Avdeling | Bergen | |
| Norway | Östfold Hospital Trust Fredrikstad | Fredrikstad | |
| Norway | Sørlandet Sykehus Kristiansand Nevrologisk avdeling | Kristiansand | |
| Norway | Akershus Universitetssykehus - Nevrologisk Avdeling | Lørenskog | |
| Norway | Molde sykehus Nevrologisk avdeling | Molde | |
| Norway | OUS Ullevål Neurology Department | Oslo | |
| Norway | St. Olavs Hospital Neurology | Trondheim | |
| Poland | Uniwersytecki Szpital Kliniczny w Bialymstoku | Bialystok | |
| Poland | Szpital Uniwersytecki Nr 2 im. J. Bizela | Bydgoszcz | |
| Poland | Copernicus PL, M.Kopernik Hospital | Gdansk | |
| Poland | Samodzielny Publiczny Specjalistyczny Szpital Zachodni | Grodzisk Mazowiecki | |
| Poland | Gornoslaskie CM im. Prof. Leszka Gieca SUM w Katowicach | Katowice | |
| Poland | Szpital Specjalistyczny im. Rydygiera | Krakow | |
| Poland | Szpital Uniwersytecki w Krakowie | Krakow | |
| Poland | Szpital im. N. Barlickiego | Lodz | |
| Poland | Wojew. Szpital Specjalistyczny im. M. Kopernika | Lodz | |
| Poland | Samodzielny Publiczny Szpital Kliniczny nr 4 | Lublin | |
| Poland | Wojewodzki Szpital Specjalistyczny im. sw. Jadwigi w Opolu | Opole | |
| Poland | SP Szpital Kliniczny nr 1 PUM im. Prof. T. Sokolowskiego | Szczecin | |
| Poland | Instytut Psychiatrii i Neurologii w Warszawie | Warszawa | |
| Poland | Szpital Wolski im. dr Anny Gostynskiej SPZOZ | Warszawa | |
| Poland | Wojskowy Instytut Medyczny | Warszawa | |
| Portugal | Hospital Garcia de Orta | Research Department | Almada | Setúbal |
| Portugal | Hospital Professor Doutor Fernando Fonseca | Neurology Department | Amadora | Lisboa |
| Portugal | BlueClinical | Centro Hospitalar Baixo Vouga - Unidade Aveiro - Gabinete de Ensaios Clinicos | Aveiro | |
| Portugal | Centro Hospitalar e Universitario de Coimbra | Hospitais da Universidade de Coimbra - Neurology Department | Coimbra | |
| Portugal | Centro Hospitalar Universitario do Algarve | Faro - Ensino, Inovacao e Investigacao - Centro de Investigacao e Documentacao | Faro | |
| Portugal | Centro Hospitalar de Lisboa Ocidental | Clin Res Dept | Lisboa | |
| Portugal | CHULN - Hospital Santa Maria | Lisboa | |
| Portugal | Luz Saude | Hospital da Luz Lisboa - Centro de Investigacao Clinica | Lisboa | |
| Portugal | Luz Saude | Hospital Beatriz Angelo - Centro de Investigacao Clinica | Loures | Lisboa |
| Portugal | ULSM - Hospital Pedro Hispano | Matosinhos | Porto |
| Portugal | Centro Hospitalar Universitario do Porto | Porto | |
| Portugal | CHUSJ - Hospital Sao Joao | Porto | |
| Portugal | Hospital de Vila Franca de Xira | Centro de Desenvolvimento e Investigacao | Vila Franca de Xira | Lisboa |
| Romania | Clinical Emergency County Hospital Brasov | Brasov | |
| Romania | Spitatul Universitar de Urgenta Bucaresti | Bucharest | |
| Romania | Institutul Clinic Fundeni | Bucuresti | |
| Romania | Institutul National de Neurologie ¿i Boli Neurovasculare | Bucuresti | |
| Romania | Spitalul Clinic de Urgenta "Prof. Dr. Nicolae Oblu" | Iasi | |
| Romania | Spitalul Clinic Judetean de Urgenta Oradea | Oradea | |
| Romania | Spitalul Clinic Judetean de Urgenta Sibiu | Sibiu | |
| Romania | Spitalul de urgenta Sf. Ioan Cel Nou | Suceava | |
| Romania | Spitalul Clinic Judetean de Urgenta Targu-Mures | Targu Mures | |
| Romania | Spitalul Clinic Judetean de Urgenta "Pius Brinzeu" Timisoara | Timisoara | |
| Slovakia | Univerzitna nemocnica Bratislava, Nemocnica ak. L.Derera | Bratislava | |
| Slovakia | Univerzitna nemocnica Bratislava, Nemocnica Ruzinov | Bratislava | |
| Slovakia | Univerzitna nemocnica Bratislava, Nemocnica Stare Mesto | Bratislava | |
| Slovakia | Dolnooravska nemocnica s poliklinikou L. Nadasi Jegeho | Dolny Kubin | |
| Slovakia | Nemocnica AGEL Komarno s.r.o. | Komarno | |
| Slovakia | Vseobecna nemocnica s poliklinikou Levoca, a.s. | Levoca | |
| Slovakia | Liptovska nemocnica s poliklinikou MUDr. Ivana Stodolu | Liptovsky Mikulas | |
| Slovakia | Vseobecna nemocnica s poliklinikou Lucenec | Lucenec | |
| Slovakia | Univerzitna nemocnica Martin | Martin | |
| Slovakia | Fakultna nemocnica Nitra | Nitra | |
| Slovakia | Fakultna nemocnica s poliklinikou J.A. Reimana | Presov | |
| Slovakia | Penta Hospitals | Rimavska Sobota Hospital - Neurology Department | Rimavska Sobota | |
| Slovakia | Fakultna nemocnica AGEL Skalica, a.s. | Skalica | |
| Slovakia | Nemocnica s poliklinikou Spisska Nova Ves a.s. | Spisska Nova Ves | |
| Slovakia | Fakultna nemocnica Trnava | Trnava | |
| Slovakia | ProCare Svet Zdravia | Vranov nad Toplou Hospital - Neurology Department | Vranov nad Toplou | |
| Slovakia | Nemocnica AGEL Ziar nad Hronom a Banska Stiavnica s.r.o. | Ziar nad Hronom | |
| Spain | Complejo Hospitalario Universitario de Albacete | Hospital General Universitario - Neurology Department, Stroke Unit | Albacete | |
| Spain | Hospital Alvaro Cunqueiro | Neurology - Stroke, No-Cardioembolic-Tia | Babio - Beade | Pontevedra |
| Spain | Hospital Universitari Germans Trias i Pujol | Badalona | Barcelona |
| Spain | Hospital de Cruces | Barakaldo | Vizcaya |
| Spain | Ciutat Sanitaria i Universitaria de la Vall d'Hebron | Barcelona | |
| Spain | Hospital de la Santa Creu i Sant Pau | Neurology Department - Stroke, No-Cardioembolic-Tia | Barcelona | |
| Spain | University Hospital of A Coruna | Neurology Department - Stroke, No-Cardioembolic-Tia | Coruña | A Coruña |
| Spain | Catalan Health Institute | Hospital Universitario de Girona Doctor Josep Trueta - Neurology Department, Stroke Unit | Girona | |
| Spain | Complejo Asistencial Universitario de Leon | Neurology Division - Stroke Unit | León | |
| Spain | Hospital Universitario Arnau de Vilanova de Lleida | Neurology Department - Clinical Neuroscience Research Group | Lleida | |
| Spain | COMPLEJO HOSPITALARIO RUBER JUAN BRAVO - Neurología | Madrid | |
| Spain | H Gregorio Marañon|Neurology|STROKE|NO-CARDIOEMBOLIC-TIA | Madrid | |
| Spain | Hospital Universitario 12 de Octubre | Madrid | |
| Spain | Hospital Universitario de La Princesa | Neurology Department | Madrid | |
| Spain | Hospital Universitario La Paz | Neurology Department - Stroke, No-Cardioembolic-Tia | Madrid | |
| Spain | Hospital Universitario Ramon y Cajal | Neurology Department - Stroke, No-Cardioembolic-Tia | Madrid | |
| Spain | Hospital Rey Juan Carlos | Neurology Department - Stroke, No-Cardioembolic-Tia | Mostoles | Madrid |
| Spain | Hospital Clinico Universitario Virgen de la Arrixaca | Neurology Department - Stroke | Murcia | |
| Spain | Hospital Clínico Universitario de Santiago de Compostela | Santiago de Compostela | A Coruña |
| Spain | Hospital Universitario Virgen Macarena | Neurology Department- Stroke, No-Cardioembolic-Tia | Sevilla | |
| Spain | Virgen del Rocio University Hospital | Neurology Department - Neurovascular Unit | Sevilla | |
| Spain | Inst Investigacio Sanitaria Pere Virgili | Hosp Univ Joan XXIII de Tarragona - Neurology - Stroke, No-Cardioembolic-Tia | Tarragona | |
| Spain | Hospital Clínico Universitario de Valencia | Neurology Department - Stroke, No-Cardioembolic-Tia | Valencia | |
| Spain | La Fe University and Polytechnic Hospital | Neurology Service - Vascular Unit | Valencia | |
| Spain | Hospital Universitario Clinico de Valladolid | Neurology Department | Valladolid | |
| Spain | Hospital Clínico Universitario Lozano Blesa | Zaragoza | |
| Sweden | Danderyds sjukhus | Danderyd | |
| Sweden | Sahlgrenska Universitetssjukhuset | Göteborg | |
| Sweden | Hässleholms Sjukhus | Hässleholm | |
| Sweden | Skånes Universitetssjukhus | Lund | |
| Sweden | Östersunds Sjukhus | Östersund | |
| Sweden | Karolinska Universitetssjukhuset Huddinge | Stockholm | |
| Sweden | Karolinska University Hospital, Solna | Stockholm | |
| Sweden | Södersjukhuset AB | Stockholm | |
| Sweden | Akademiska Sjukhuset | Uppsala | |
| Switzerland | Kantonsspital Baden | Baden | |
| Switzerland | Universitätsspital Basel | Basel | Basel-Stadt |
| Switzerland | Inselspital Universitätsspital Bern | Bern | |
| Switzerland | Hôpital Cantonal Universitaire de Genève | Geneva | Genève |
| Switzerland | Centre Hospitalier Universitaire Vaudois (CHUV) | Lausanne | Vaud |
| Switzerland | Ospedale regionale di Lugano | Lugano | Ticino |
| Switzerland | Kantonsspital St. Gallen | Saint Gallen | Sankt Gallen |
| Switzerland | Hospital Cantonal Fribourg | Villars sur Glâne | |
| Switzerland | NeuroZentrum Hirslanden | Zürich | |
| Taiwan | Changhua Christian Hospital | Changhua | |
| Taiwan | National Taiwan University Hospital, Hsin-Chu Branch | Hsinchu | |
| Taiwan | Chang Gung Memorial Hospital Kaohsiung | Kaohsiung | |
| Taiwan | Kaohsiung Medical University Chung-Ho Memorial Hospital | Kaohsiung City | Kaohsiung |
| Taiwan | Kaohsiung Veterans General Hospital | Kaohsiung City | |
| Taiwan | Chang Gung Memorial Hospital Keelung | Keelung | |
| Taiwan | En Chu Kong Hospital | New Taipei City | Taipei |
| Taiwan | Far Eastern Memorial Hospital Neurology | New Taipei City | Taipei |
| Taiwan | Fu Jen Catholic University Hospital | New Taipei City | Taipei |
| Taiwan | MacKay Memorial Hospital Tamsui Branch | New Taipei City | Taipei |
| Taiwan | Taipei Medical University - Shuang Ho Hospital | New Taipei City | |
| Taiwan | China Medical University Hospital | Taichung | |
| Taiwan | Taichung Veterans General Hospital | Taichung | |
| Taiwan | National Cheng Kung University Hospital | Tainan | |
| Taiwan | Mackay Memorial Hospital | Taipei | |
| Taiwan | National Taiwan University Hospital | Taipei | |
| Taiwan | Shin Kong Wu Ho-Su Memorial Hospital | Taipei | |
| Taiwan | Taipei Municipal Wanfang Hospital | Taipei | |
| Taiwan | Taipei Veterans General Hospital | Taipei | |
| Taiwan | Tri-Service General Hospital | Taipei | |
| Taiwan | Chung Shan Medical University Hospital | Taizung | |
| Taiwan | Chang Gung Memorial Hospital at Linkou | Taoyuan | |
| Taiwan | China Medical University Hospital Hsin-Chu Branch | Zhubei City | Hsinchu |
| Turkey | Ankara Universitesi Tip Fakultesi Hastanesi | Ankara | |
| Turkey | Gazi Universitesi Tip Fakultesi | Ankara | |
| Turkey | Hacettepe Universitesi Tip Fakultesi | Ankara | |
| Turkey | Health Ministry Of Türkiye Republic Ankara Bilkent City Hospital | Ankara | |
| Turkey | Akdeniz Universitesi Tip Fakultesi Hastanesi | Antalya | |
| Turkey | Firat Universitesi Tip Fakultesi | Elazig | |
| Turkey | Eskisehir Osmangazi Universitesi Tip Fakultesi | Eskisehir | |
| Turkey | Bakirkoy Prof Dr Mazhar Osman Ruh Sagligi ve Sinir Hast. EAH | Istanbul | |
| Turkey | Istanbul Sultan 2. Abdulhamid Han Egitim ve Arastirma Has. | Istanbul | |
| Turkey | Istanbul Universitesi Istanbul Tip Fakultesi | Istanbul | |
| Turkey | Kartal Dr Lutfi Kirdar Sehir Hastanesi | Istanbul | |
| Turkey | Marmara Uni. Tip Fak. Pendik EAH Noroloji | Istanbul | |
| Turkey | Dokuz Eylul Universitesi Tip Fakultesi | Izmir | |
| Turkey | Ege Universitesi Tip Fakultesi | Izmir | |
| Turkey | Saglik Bilimleri Universitesi Izmir Tepecik EAH | Izmir | |
| Turkey | Necmettin Erbakan Universitesi Meram Tip Fakultesi Hastanesi | Konya | |
| Turkey | Selcuk University Faculty of Medicine | Konya | |
| Turkey | Ondokuz Mayis Uni Tip Fakultesi | Samsun | |
| Turkey | Samsun Egitim Arastirma Hastanesi | Samsun | |
| Turkey | Cumhuriyet Universitesi Tip Fakultesi | Sivas | |
| United Kingdom | Kent and Canterbury Hospital | Stroke Unit | Canterbury | Kent |
| United Kingdom | Royal Derby Hospital Derby Teaching Hospitals NHS Foundation | Derby | |
| United Kingdom | Edinburgh Royal Infirmary | Edinburgh | |
| United Kingdom | Royal Devon & Exeter Hospital | Exeter | |
| United Kingdom | Glasgow Royal Infirmary | Glasgow Clinical Research Facility | Glasgow | |
| United Kingdom | St George's Hospital | Kogarah | London |
| United Kingdom | Leeds General Infirmary | Leeds | West Yorkshire |
| United Kingdom | Aintree University Hospital | Liverpool | |
| United Kingdom | Charing Cross Hospital | London | |
| United Kingdom | King's College Hospital - NHS Foundation Trust | London | |
| United Kingdom | Royal Victoria Infirmary | Newcastle Upon Tyne | Tyne And Wear |
| United Kingdom | John Radcliffe Hospital | Oxford | |
| United Kingdom | Salford Royal Hospital | Salford | Manchester |
| United Kingdom | Southampton General Hospital | Southampton | Hampshire |
| United Kingdom | Royal Stoke University Hospital | Stoke on Trent | Staffordshire |
| United Kingdom | Sunderland Royal Hospital | Sunderland | Tyne And Wear |
| United States | Albany Medical College | Department of Neurology | Albany | New York |
| United States | Lehigh Neurology | Allentown | Pennsylvania |
| United States | Mission Hospital | Neurology | Asheville | North Carolina |
| United States | HCA Florida JFK Hospital | Atlantis | Florida |
| United States | University of Maryland | Baltimore | Maryland |
| United States | Mid-Atlantic Epilepsy and Sleep Center | Bethesda | Maryland |
| United States | Tufts Medical Center - Boston | Boston | Massachusetts |
| United States | Delray Medical Center | Boynton Beach | Florida |
| United States | Nova Clinical Research | Blake Medical Center Center | Bradenton | Florida |
| United States | Nova Clinical Research | Manatee Memorial Hospital | Bradenton | Florida |
| United States | SUNY Downstate Medical Center | Brooklyn | New York |
| United States | Trinity Medical Western New York | Trinity Vascular & Endovascular Center - Research Department | Buffalo | New York |
| United States | University of North Carolina | Chapel Hill | North Carolina |
| United States | Medical University of South Carolina | MUSC Center for Womens Health - Department of Obstetrics and Gynecology | Charleston | South Carolina |
| United States | Erlanger Health, Inc. | Chattanooga | Tennessee |
| United States | The University of Chicago | Chicago | Illinois |
| United States | University of Illinois at Chicago | Department of Neurology | Chicago | Illinois |
| United States | BayCare Health System | Morton Plant Hospital, Neuroscience Research department | Clearwater | Florida |
| United States | Cleveland Clinic Foundation | Cleveland | Ohio |
| United States | University of Missouri Health Care | Columbia | Missouri |
| United States | Ohio State University Wexner Medical Center | Columbus | Ohio |
| United States | OhioHealth Research Institute | Columbus | Ohio |
| United States | Baylor University Medical Center at Dallas | Dallas | Texas |
| United States | University of Texas Southwestern Medical Center | Dallas | Texas |
| United States | Nuvance Health | Danbury | Connecticut |
| United States | Wright State University | Boonshoft School of Medicine - WSU and Premier Health Clinical Trials Research Alliance | Dayton | Ohio |
| United States | Henry Ford Hospital | Detroit | Michigan |
| United States | Duke Univ. Medical Center | Durham | North Carolina |
| United States | Michigan State University | East Lansing | Michigan |
| United States | Doctors Hospital at Renaissance | Edinburg | Texas |
| United States | University of Pittsburgh Medical Center, Hamot | Clinical Trials and Research | Erie | Pennsylvania |
| United States | Eastern Shore Research Institute, LLC | Fairhope, AL | Fairhope | Alabama |
| United States | Kaiser Permanente Fontana Medical Center | Fontana | California |
| United States | Texas Health Harris Methodist Hospital | Fort Worth | Texas |
| United States | University of Florida Health Sciences Center | Gainesville | Florida |
| United States | Minneapolis Clinic of Neurology | Golden Valley, MN | Golden Valley | Minnesota |
| United States | Northwell Health Neuroscience Institute | Great Neck | New York |
| United States | Guilford Neurologic Research, PA | Greensboro | North Carolina |
| United States | ECU Health Medical Center | Greenville | North Carolina |
| United States | Prisma Health | PH Greenville Memorial Hospital - Cerebrovascular & Stroke Center of the Neurology Department - Stroke Program | Greenville | South Carolina |
| United States | Hackensack University Medical Center | Hackensack | New Jersey |
| United States | Valley Baptist Health System | Harlingen - Clinical Research | Harlingen | Texas |
| United States | University of Pittsburgh Medical Center | Harrisburg | Pennsylvania |
| United States | Westchester Medical Center | Hawthorne | New York |
| United States | Neurological Associates - Henrico | Henrico | Virginia |
| United States | Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania |
| United States | Houston Methodist Hospital | Houston | Texas |
| United States | University of Texas Health Science Center at Houston | Houston | Texas |
| United States | University Physicians and Surgeons | Huntington | West Virginia |
| United States | University of Mississippi Medical Center | Shafi Group | Jackson | Mississippi |
| United States | Baptist Health Research Institute | Jacksonville | Florida |
| United States | Kansas City VA Medical Center | Kansas City | Missouri |
| United States | St. Luke's Hospital of Kansas City | Kansas City | Missouri |
| United States | Kettering Health Network | Research Institute | Kettering | Ohio |
| United States | University of Tennessee Medical Center | Knoxville | Tennessee |
| United States | Lancaster General Hospital | Lancaster | Pennsylvania |
| United States | Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire |
| United States | Baptist Health Lexington | Lexington | Kentucky |
| United States | Bon Secours Mercy Health | Lima | Ohio |
| United States | University of Arkansas for Medical Sciences | Little Rock | Arkansas |
| United States | MemorialCare Health System | Long Beach | California |
| United States | Kaiser Permanente Los Angeles Medical Center | Los Angeles | California |
| United States | Ronald Reagan UCLA Medical Center | Los Angeles | California |
| United States | University of Southern California Keck School of Medicine | Los Angeles | California |
| United States | Loyola University Medical Center | Maywood | Illinois |
| United States | Baptist Memorial Hospital East | Memphis | Tennessee |
| United States | Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin |
| United States | Froedtert Health/Medical College of Wisconsin | Milwaukee | Wisconsin |
| United States | Inspira Medical Centers | Clinical Research Office | Mullica Hill | New Jersey |
| United States | Intermountain Healthcare | Cardiovascular Research Department | Murray | Utah |
| United States | Yale University | School of Medicine - Department of Neurology | New Haven | Connecticut |
| United States | Ochsner Health System | Ochsner Clinic Foundation - Neuroscience Research Department | New Orleans | Louisiana |
| United States | Columbia University | New York | New York |
| United States | Icahn School of Medicine at Mount Sinai | New York | New York |
| United States | Mount Sinai Hospital - Stroke Center | New York | New York |
| United States | NYU Langone Medical Center | New York | New York |
| United States | ChristianaCare Health Services | Christiana Hospital - Emergency Medicine Research | Newark | Delaware |
| United States | Hoag Memorial Hospital - Center for Research & Education | Newport Beach | California |
| United States | Mercy Hospital Oklahoma City | Oklahoma City | Oklahoma |
| United States | University of Oklahoma Med Center | Oklahoma City | Oklahoma |
| United States | UC Irvine Medical Center | Orange | California |
| United States | Einstein Healthcare Network | Philadelphia | Pennsylvania |
| United States | Lewis Katz School of Medicine at Temple University - Neurolo | Philadelphia | Pennsylvania |
| United States | The Hospitals of the University of Pennsylvania | Philadelphia | Pennsylvania |
| United States | Thomas Jefferson University | Philadelphia | Pennsylvania |
| United States | St. Joseph's Hosp | Barrow Neuro Institute | Phoenix | Arizona |
| United States | Neurology Consultants of Dallas, PA | Plano | Texas |
| United States | Trinity Health | Oakland Hospital - Clinical Research Department | Pontiac | Michigan |
| United States | Oregon Health and Science University | Portland | Oregon |
| United States | Vassar Brothers Medical Center | Poughkeepsie | New York |
| United States | Rhode Island Hospital | Providence | Rhode Island |
| United States | Long Island Jewish Medical Center | Queens | New York |
| United States | NC Heart & Vascular Research | Raleigh | North Carolina |
| United States | Bon Secours St. Mary's Hospital | Richmond | Virginia |
| United States | Mayo Clinic - Rochester | Rochester | Minnesota |
| United States | Rochester General Hospital | Rochester | New York |
| United States | Mercyhealth Javon Bea Hospital - Riverside | Neurology Research Department | Rockford | Illinois |
| United States | University of California Davis Medical Center | Sacramento | California |
| United States | Barnes-Jewish Hospital | Saint Louis | Missouri |
| United States | Mercy Hospital | Saint Louis | Missouri |
| United States | Mercy Hospital South | Saint Louis | Missouri |
| United States | University of Utah Health Care | Salt Lake City | Utah |
| United States | University of Texas Health San Antonio | San Antonio | Texas |
| United States | San Francisco VA Health Care System | San Francisco | California |
| United States | Cottage Health I Santa Barbara Cottage Hospital - Research Department | Santa Barbara | California |
| United States | Intercoastal Medical Group | Clinical Research | Sarasota | Florida |
| United States | HonorHealth | Scottsdale | Arizona |
| United States | Ochsner LSU Health Shreveport | Shreveport | Louisiana |
| United States | HSHS Medical Group | Springfield | Illinois |
| United States | Stanford University Medical Center | Stanford | California |
| United States | BayCare Health System | Saint Joseph's Hospital - Neurology Department | Tampa | Florida |
| United States | University of South Florida | Tampa | Florida |
| United States | Baylor Scott & White | Temple | Texas |
| United States | Mercy Health St. Vincent Medical Center | Toledo | Ohio |
| United States | ProMedica | ProMedica Toledo Hospital - Neuro/Stroke Research Department | Toledo | Ohio |
| United States | Harbor - UCLA Medical Center | Torrance | California |
| United States | Cardiology Associates of Fairfield County, PC - Trumbull | Trumbull | Connecticut |
| United States | Banner - University Medical Center Tucson | Tucson | Arizona |
| United States | Novant Health Forsyth Medical Center | Winston-Salem | North Carolina |
| United States | Wake Forest University School of Medicine | Winston-Salem | North Carolina |
| United States | Mercy Health St. Elizabeth Youngstown Hospital | Youngstown | Ohio |
| Lead Sponsor | Collaborator |
|---|---|
| Bayer |
United States, Argentina, Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Colombia, Czechia, Denmark, Finland, France, Germany, Greece, Hungary, India, Israel, Italy, Japan, Kazakhstan, Korea, Republic of, Latvia, Lithuania, Malaysia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Spain, Sweden, Switzerland, Taiwan, Turkey, United Kingdom,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Time to first occurrence of ischemic stroke | Up to 31 months | ||
| Primary | Time to first occurrence of ISTH major bleeding | ISTH=International Society on Thrombosis and Hemostasis | Up to 31 months | |
| Secondary | Time to first occurrence of all strokes (ischemic and hemorrhagic) | Up to 31 months | ||
| Secondary | Time to first occurrence of composite of CV death, MI or stroke | CV=Cardiovascular, MI=Myocardial infarction | Up to 31 months | |
| Secondary | Time to first occurrence of composite of all-cause mortality, MI or stroke | Up to 31 months | ||
| Secondary | Time to first occurrence of disabling stroke (mRS =3 at 90 days) | mRS=Modified Rankin Scale | Up to 31 months | |
| Secondary | Time to first occurrence of all-cause mortality | Up to 31 months | ||
| Secondary | Time to first occurrence of transient ischemic attack (TIA) | Up to 31 months | ||
| Secondary | Time to first occurrence of composite of ISTH major or clinically relevant non-major bleeding | Up to 31 months | ||
| Secondary | Time to first occurrence of ISTH clinically relevant non-major bleeding | Up to 31 months | ||
| Secondary | Time to first occurrence of symptomatic intracranial hemorrhage | Up to 31 months | ||
| Secondary | Time to first occurrence of hemorrhagic stroke | Up to 31 months | ||
| Secondary | Time to first occurrence of fatal bleeding | Up to 31 months | ||
| Secondary | Time to first occurrence of minor bleeding | Up to 31 months | ||
| Secondary | Time to first occurrence of composite of ischemic stroke or ISTH major bleeding | Up to 31 months | ||
| Secondary | Time to first occurrence of composite of CV death, all stroke, MI or ISTH major bleeding | Up to 31 months | ||
| Secondary | Time to first occurrence of composite of all-cause mortality, disabling stroke, fatal bleeding, symptomatic intracranial hemorrhage | Up to 31 months | ||
| Secondary | Time to first occurrence of ischemic stroke in the first 90 days | Up to 31 months |
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04304508 -
Study to Gather Information About Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following a Recent Non Cardioembolic Ischemic Stroke Which Occurs When a Blood Clot Has Formed Somewhere in the Human Body (But Not in the Heart) Travelled to the Brain.
|
Phase 2 |