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Clinical Trial Summary

The purpose of this research is to compare the efficacy of immediate versus extended-release melatonin as a supplement affecting the sleep cycle in patients with Parkinson disease and Rapid Eye Movement Sleep Behavior Disorder.


Clinical Trial Description

Enrolled patients with Parkinson disease and previously diagnosed rapid eye movement sleep behavior disorder, who are being treated at Mayo Clinic in Florida, will be randomized to receive either immediate-release melatonin or extended-release melatonin and then will be crossed over to receive the opposite intervention. The study will consist of two treatment periods of 4 weeks separated by a washout period of 2 weeks. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05307770
Study type Interventional
Source Mayo Clinic
Contact
Status Terminated
Phase N/A
Start date May 1, 2022
Completion date February 1, 2024

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