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NCT ID: NCT05528003 Completed - Clinical trials for Minimally Invasive Surgical Procedures

Homemade Versus Commercialized Single-access Port Devices in Single-incision Laparoscopic Appendectomy

Start date: June 1, 2013
Phase:
Study type: Observational

Homemade and commercialized single-assess port devices are two kinds of port devices commonly used for single-incision laparoscopic appendectomy. This study aimed to compare these two port devices in terms of short-term surgical outcomes and medical costs.

NCT ID: NCT05527756 Completed - Scar Clinical Trials

Evaluation of the Cosmetic Outcomes of Totally Endoscopic Cardiac Surgery

SCARMICS
Start date: October 21, 2022
Phase:
Study type: Observational

Totally endoscopic cardiac surgery (TECS) is considered to have aesthetic advantages over conventional median sternotomy due to the smaller incisions. Most research regarding TECS focuses on clinical outcomes instead of cosmetic consequences. Following surgery, postoperative scarring is unavoidable and may negatively affect the patient's physical and emotional well-being. Therefore, this study aims to investigate the cosmesis after TECS.

NCT ID: NCT05526911 Completed - Tuberculosis Clinical Trials

A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults

Start date: July 20, 2022
Phase: Phase 1
Study type: Interventional

A Phase 1, Drug-Drug Interaction Study to Evaluate the Safety, Tolerability, and the Induction Potential of TBAJ-876 on CYP3A4 and P-glycoprotein and the Inhibition Potential of TBAJ-876 on P-glycoprotein in Healthy Adult Subjects

NCT ID: NCT05523427 Completed - Clinical trials for Irritable Bowel Syndrome

Probiotics as Adjuvant Therapy in the Management of Irritable Bowel Syndrome

Start date: July 19, 2022
Phase: N/A
Study type: Interventional

Studying the effects of adding probiotics to the drug regimen of patients with diarrhea predominant IBS

NCT ID: NCT05523180 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

A Study to Evaluate the Effect of Probiotic Supplement on Quality of Life

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

This study aims to evaluate the impact of a specific oral probiotic blend on the quality of life of adults with respiratory conditions.

NCT ID: NCT05522478 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Effect Of Methylphenidate On Balance In Children With Attention Deficit Hyperactivity Disorder

Start date: July 2016
Phase:
Study type: Observational

Attention Deficit Hyperactivity Disorder is a neurodevelopmental disorder that may have poor motor coordination and balance control. The effect of Methylphenidate treatment on balance and fall risk is still unclear. This study aimed to evaluate the effect of methylphenidate (MPH) treatment on balance, fall risk, and sensorimotor integration in children with Attention Deficit Hyperactivity Disorder (ADHD).

NCT ID: NCT05522023 Completed - Surgery Clinical Trials

Effects of Aromatic Solution Applied After Surgery

Start date: February 15, 2021
Phase: N/A
Study type: Interventional

Today, surgical applications are used to solve many health problems. In order for the surgical intervention to take place, anesthesia applications are often required. Complications such as sore throat, thirst and nausea and vomiting may occur as a result of trauma, local irritation and inflammation of the airway mucosa during anesthesia and tracheal intubation. These complications are in the postoperative period; It may cause delayed oral fluid intake, prolonged dehydration, oral odour, and increased risk of aspiration, hematoma and wound dehiscence due to retching and vomiting, all of which may lead to delayed discharge and increased cost. Aromatherapy, one of the non-pharmacological applications, is frequently applied in reducing postoperative complications and its effectiveness is stated. In this study, the aromatic solution applied after the surgery; It was planned to examine the effect on sore throat, thirst, nausea-vomiting. In addition, the multimodal synergistic effect of lavender oil and ginger oil used in the aromatic solution to be prepared will be utilized. As a result of this study, the effectiveness of the aromatic solution application to be applied to the patients in the postoperative period and the benefits and benefits of the patient's recovery process will be determined. Thus, effective application can be made for the entire postoperative period. It is thought that this study to be conducted will be a guide for future studies on the patient group.

NCT ID: NCT05521815 Completed - Clinical trials for Traumatic Brain Injury With Loss of Consciousness

Effect of Early Coma Arousal Therapy on Conscious Level Recovery and Cognition in Traumatic Brain Injury

Start date: August 23, 2022
Phase: N/A
Study type: Interventional

PURPOSE: The aim of this study is to investigate the effect of early coma arousal therapy on conscious level and cognitive function in sever traumatic brain injury patients. BACKGROUND: Traumatic brain injury (TBI) could be simply defined as an alteration in brain function due to external forces and is considered as one of the leading cause of death and disability worldwide, especially among young adults and the elderly. Current estimates imply that annual incidence of TBI is 50-60 million worldwide, and specifically for Europe and USA, 0.5% of Europeans and 1.1% of Americans are experiencing a TBI each year. The original scale has since been revised and is known as the Rancho Los Amigos Revised Scale (RLAS-R). One of the limitations of the original eight level scale was that it did not accurately reflect the individuals with higher levels of recovery. Two more levels were added to the initial eight level Ranchos Scale to create a more comprehensive ten level scale named the Rancho Los Amigos Revised Scale (RLAS-R).

NCT ID: NCT05520138 Completed - Clinical trials for Prostatic Neoplasms, Castration-Resistant

Enzalutamide vs. Abiraterone in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC)

Start date: August 29, 2022
Phase:
Study type: Observational

This study will be a retrospective data analysis to compare outcomes between patients with chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC) who initiated enzalutamide and those who initiated abiraterone using the 100% Fee-For-Service Medicare claims data. The study will address the following objectives: Primary objective: To compare overall survival (OS) in patients with chemotherapy-naïve mCRPC who initiated enzalutamide vs. abiraterone Secondary objectives: - To compare OS in patients with chemotherapy-naïve mCRPC who received only enzalutamide without any subsequent therapy vs. abiraterone without any subsequent therapy - To compare treatment duration and time to subsequent therapy in chemotherapy-naïve mCRPC patients initiating enzalutamide vs. abiraterone

NCT ID: NCT05519345 Completed - Clinical trials for Anterior Cruciate Ligament Injuries

Operant Conditioning After ACL Reconstruction

Start date: December 28, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to examine if the changes in corticospinal function that accompany ACL reconstruction can be improved through a form of mental coaching and encouragement, known as operant conditioning.