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NCT ID: NCT05533944 Completed - Simulation Training Clinical Trials

Fast-tracking ERCP Learning: Does Training on a Mechanical Simulator Improve Trainee's Clinical Performance?

Start date: September 12, 2022
Phase: N/A
Study type: Interventional

The hypothesis of this study is that novice trainees who are offered early simulation training in Boškoski-Costamagna ERCP Trainer in addition to routine hands-on training (intervention group) will demonstrate improved clinical outcomes compared to those undergoing routine hands-on ERCP training only (control group).

NCT ID: NCT05533736 Completed - Clinical trials for Cutaneous Leishmaniasis, American

Feasibility and Usability of Mobile Applications for Monitoring Cutaneous Leishmaniasis Treatment in Colombia

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

An effectiveness-implementation sequential explanatory hybrid design type 2 was performed in two rural communities of Colombia. A quasi-experimental study with historical control (standard of care) was designed to estimate the effectiveness of community-based intervention using the Guaral+ST mobile application (app). Three implementation outcomes were evaluated: acceptability and usability by qualitative methods, and fidelity by quantitative methods

NCT ID: NCT05532618 Completed - Clinical trials for Anterior Cruciate Ligament Injuries

Efficacy of Adductor Canal Block for Anterior Cruciate Ligament Surgery

DUAL
Start date: August 1, 2022
Phase: N/A
Study type: Interventional

The goal of this study is to objectify the postoperative pain level, the use of opiates and postoperative nausea and vomiting after adding the adductor canal block to the standard pain regiment after anterior cruciate ligament surgery

NCT ID: NCT05531760 Completed - Clinical trials for Pseudophakic Bullous Keratopathy

Predictive Factors of Graft Detachment Following Dmek

PDF DMEKDETACH
Start date: March 1, 2022
Phase:
Study type: Observational

The aim of this study was to identify the predictive factors of graft detachment after Descemet Membrane Endothelial Keratoplasty (DMEK) surgery. This retrospective study was conducted on patients aged 18 years, with Fuchs' dystrophy (FECD) or pseudophakic bullous keratopathy (PBK), who were scheduled for DMEK or triple-DMEK (combined phacoemulsification and DMEK surgery). Patients with a history of surgery other than cataract surgery were excluded. The study was conducted between 2014 and 2022 and follow-up was for 3 months. The characteristics of patients with and without graft detachment following surgery were compared using logistic regression.

NCT ID: NCT05531721 Completed - Clinical trials for Hemophagocytic Lymphohistiocytoses

HLH Patients - a Retrospective Study

Start date: November 10, 2022
Phase:
Study type: Observational

Monocentric, observational, retrospective, no profit study aimed to analyze factors that are significantly impacting the outcome of patients diagnosed with HLH.

NCT ID: NCT05531435 Completed - Clinical trials for Dental Caries in Children

Local Anesthesia With Computerized Device for Restorative Procedures in Pediatric Patients

Start date: September 7, 2022
Phase: N/A
Study type: Interventional

The aim of the present study is to assess if there are differences on perceived pain during local anesthesia performed with SleeperOne device or with a traditional syringe in pediatric patients. Patients responding to the inclusion criteria will be asked to participate to the study. After signing the informed consent, they will undergo local anesthesia procedure on first or second primary molars for the subsequent performing of dental filling. The split-mouth design will randomly allocate first or second primary molar from one quadrant to SleeperOne procedure, while the contralateral one will be subdued to local anesthesia with traditional syringe. After the procedure, patients will be asked to assess the perceived pain with a Visual Analogue Scale from a range 0-10. VAS scales will be used to assess sensations of "size" (related to the two instruments), bitter and vomit.

NCT ID: NCT05529511 Completed - Rehabilitation Clinical Trials

The POP-ACLR Study

POP-ACLR
Start date: August 3, 2022
Phase:
Study type: Observational

The anterior cruciate ligament is one of four key ligaments in the knee. It is the most commonly injured knee ligament with an estimated 200,000 injuries occurring each year in the US (UK data unavailable). Surgery is currently standard treatment for this injury and helps patients return to work and their preinjury activity levels (such as running, playing football or netball). Patients expect surgery to be successful. However, the number of patients who are able to return to their normal activities is low, with only 24% returning at 1 year after surgery. Research has shown that after surgery, patients lack confidence, feel fearful about reinjuring their knee and need to continue to seek advice from healthcare professionals. Receiving physiotherapy before surgery (called 'prehabilitation') is recommended by researchers and physiotherapists to help patients prepare for surgery and postoperative rehabilitation. Although physiotherapy is recommended, some patients don't receive any treatment before their operation, but it is not known why this might be. There are also no guidelines for the treatment patients receive and current treatment varies. If an intervention to be delivered to patients prior to anterior cruciate ligament surgery (prehabilitation treatment package) is developed, patient care may be improved. Patient outcomes could also be improved resulting in more patients returning to physical activity after surgery. This study will firstly, interview participants at three different time points along the patient pathway (1) 12 participants up to 2 weeks before surgery, (2) 12 participants 3 months after surgery, (3) 12 participants 12 months after surgery. The interviews will allow participants to tell the story of their experiences from the point of receiving their injury diagnosis to returning to physical activity and what they expect from their surgery. Secondly, the prehabilitation treatment package will be designed with healthcare professionals, therapy managers and patients.

NCT ID: NCT05529173 Completed - Clinical trials for Surgical Wound Infection

Povidone-Iodine for Nasal Decolonization

Start date: September 6, 2022
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy and tolerability of 10% povidone-iodine in eliminating nasal carriage of Staphylococcus aureus and MRSA. To determine whether a more convenient, single-dose, pre-operative 10% povidone-iodine (PI) application is effective in reducing nasal carriage of S. aureus and MRSA. We expect a statistically significant decrease in S. aureus/MRSA colonization in nasal cultures taken perioperatively after intervention in patients who received pretreatment with PI as compared to patients who received normal saline (NS).

NCT ID: NCT05528627 Completed - Anesthesia Clinical Trials

PECs for Implantable Cardiac Electronic Device Insertion

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the feasibility of the Pectoralis Nerve (PECS) block for CIED insertion.

NCT ID: NCT05528120 Completed - Clinical trials for Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion

Food Effect Study on the Pharmacokinetics of VC004 Capsules in Healthy Adult Subjects

Start date: October 20, 2022
Phase: Phase 1
Study type: Interventional

This study will adopt a randomized, open-label, two-period, 2-way crossover design to evaluate pharmacokinetics of a single oral dose of VC004 capsules under fasting and fed conditions in healthy subjects.