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NCT ID: NCT00052715 Terminated - Clinical trials for Brain and Central Nervous System Tumors

Biological Therapy and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Poly-ICLC
Start date: October 23, 2002
Phase: Phase 2
Study type: Interventional

RATIONALE: Biological therapies such as poly-ICLC use different ways to stimulate the immune system and stop tumor cells from growing. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining biological therapy with radiation therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining poly-ICLC with radiation therapy in treating patients who have newly diagnosed glioblastoma multiforme.

NCT ID: NCT00052598 Terminated - Clinical trials for Recurrent Adult Acute Myeloid Leukemia

Therapeutic Allogeneic Lymphocytes and Aldesleukin in Treating Patients With High-Risk or Recurrent Myeloid Leukemia After Undergoing Donor Stem Cell Transplant

Start date: September 2002
Phase: Phase 1/Phase 2
Study type: Interventional

This phase I/II trial is studies the side effects of giving therapeutic allogeneic lymphocytes together with aldesleukin and to see how well it works in treating patients with high-risk or recurrent myeloid leukemia after undergoing donor stem cell transplant. Biological therapies, such as therapeutic autologous lymphocytes, may stimulate the immune system in different ways and stop cancer cells from growing. Aldesleukin may stimulate the white blood cells to kill cancer cells. Giving therapeutic autologous lymphocytes together with aldesleukin may kill more cancer cells

NCT ID: NCT00052585 Terminated - Clinical trials for Recurrent Rectal Cancer

Gefitinib and Combination Chemotherapy in Treating Patients With Advanced or Recurrent Colorectal Cancer

Start date: October 2002
Phase: Phase 2
Study type: Interventional

Phase II trial to study the effectiveness of combining gefitinib with fluorouracil, leucovorin, and irinotecan in treating patients who have advanced or recurrent colorectal cancer. Biological therapies such as gefitinib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining gefitinib with fluorouracil, leucovorin, and irinotecan may kill more tumor cells

NCT ID: NCT00052377 Terminated - Clinical trials for Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma

Interleukin-12 and Interleukin-2 in Treating Patients With Mycosis Fungoides

Start date: September 2002
Phase: Phase 1/Phase 2
Study type: Interventional

Phase I/II trial to study the effectiveness of combining interleukin-12 with interleukin-2 in treating patients who have mycosis fungoides. Biological therapies, such as interleukin-12 and interleukin-2, use different ways to stimulate the immune system and stop cancer cells from growing. Combining more than one biological therapy may kill more tumor cells

NCT ID: NCT00051766 Terminated - HIV Infections Clinical Trials

Computer-Assisted Adherence Program for Patients Taking Anti-HIV Drugs

Start date: n/a
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of a computer-assisted, self-administered adherence program for patients on complicated anti-HIV drug regimens.

NCT ID: NCT00049959 Terminated - Clinical trials for Basal Cell Carcinoma

Two Studies to Determine if Verteporfin PDT is Effective & Safe in Treating Multiple Basal Cell Carcinoma of the Skin.

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of the two studies is to determine whether an experimental therapy using a photoactive drug, verteporfin, in combination with direct light exposure of basal cell carcinoma of the skin can safely eliminate these skin tumors.

NCT ID: NCT00049738 Terminated - Schizophrenia Clinical Trials

Screening for Childhood-Onset Psychotic Disorders

Start date: October 29, 2002
Phase: N/A
Study type: Observational

The purpose of this study is to screen and evaluate children with psychotic disorders to establish or confirm their diagnosis and to collect data about their condition. This study will also recruit individuals for various treatment studies. Childhood psychotic disorders are debilitating conditions in which children have auditory or visual hallucinations and disorganized thoughts. This study will examine psychotic disorders in children in an inpatient setting. Participants in this study will be admitted to the NIH Clinical Center for up to 9 weeks under one or more of the following conditions: current medication, no medication, or tapered medication. Participants will undergo blood, urine, metabolic, and intellectual functioning tests. An electrocardiogram (EKG) and electroencephalogram (EEG) will be performed. A magnetic resonance imaging (MRI) scan of the brain will be taken and infrared oculography will be used to measure eye movements. Participants and their family members may also be asked to participate in a study of genetics in children with psychotic illnesses. Children meeting criteria for childhood onset schizophrenia may be offered participation in a medication comparison protocol.

NCT ID: NCT00049582 Terminated - Clinical trials for Recurrent Adult Acute Myeloid Leukemia

Decitabine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia

Start date: September 2002
Phase: Phase 1
Study type: Interventional

This phase I trial is studying the side effects and best dose of decitabine in treating patients with myelodysplastic syndromes or acute myeloid leukemia. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die.

NCT ID: NCT00049088 Terminated - Clinical trials for Unspecified Adult Solid Tumor, Protocol Specific

Bortezomib and Docetaxel in Treating Patients With Advanced Solid Tumors

Start date: August 2002
Phase: Phase 1
Study type: Interventional

Phase I trial to study the effectiveness of combining bortezomib with docetaxel in treating patients who have advanced solid tumors. Bortezomib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining bortezomib with docetaxel may kill more tumor cells

NCT ID: NCT00048659 Terminated - Prostatic Neoplasms Clinical Trials

YM598 Added to Mitoxantrone/Prednisone to Control Pain in Metastatic Prostate Cancer Patients No Longer Responding to Hormone Therapy

Start date: n/a
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if patients who take YM598 in addition to mitoxantrone and prednisone (standard therapy) experience improvement in the pain associated with prostate cancer metastases in the bone.