Effects of Physical Activity on Weight Loss and Weight Maintenance in Obese Adults - Three Year Follow-up Study

Obesity Clinical Trial

— LILA  

Official title:

Effects of Physical Activity on Weight Loss and Weight Maintenance in Obese Adults - Three Year Follow-up Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03861754
• Other study ID #: 147/2006
• Status: Completed
• Phase: N/A
• Start date: January 28, 2004
• Est. completion date: May 2010

Study information

• Verified date: February 2019
• Source: University of Oulu
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Objective To study if exercise added to weight loss treatment at the beginning of the weight loss intervention or at 6 months could sustain the weight loss achieved or give extra boost for weight reduction.

Design 36-month, 4-group parallel, randomized trial.

Setting Oulu, Finland.

Participants 120 obese adults (body mass index ≥ 30).

Intervention Participants were randomly assigned to behavioural modification (iBM) (n = 30), behavioural modification + exercise from 0 to 3 months (CWT1) (n = 30), behavioural modification + exercise from 6 to 9 months (CWT2) (n = 30), and a control group (CON) (n = 30). Questionnaires and measurements were performed at baseline, 3,9,4 and 36 months. The intervention consisted of an intensified weight loss period (1-12 months) followed by a weight maintenance period (13-36 months). Intensified behavioural modification included 14 individual face to face meetings, eleven times with a personal therapist (qualified nurse) and three times with a nutritionist. Weight maintenance period included six individual meetings with personal therapist. Twelve weeks supervised exercise was offered three times a week, 40 minutes at a time. In the CWT1 group supervised exercise was offered at months 1-3 and in the CWT2 group at months 4-6.

Measurements Body weight (primary outcome) and waist circumference (secondary outcome)

Recruitment information / eligibility

• Status: Completed
• Enrollment: 120
• Est. completion date: May 2010
• Est. primary completion date: May 2010
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 64 Years

Eligibility

Inclusion Criteria:

• Body mass Index > 30

• Age 18-64

Exclusion Criteria:

• Pregnancy

• Health reasons preventing exercise and exercise test

• Medication preventing exercise and exercise test

• Previously diagnosed diabetes

Related Conditions & MeSH terms

• Body Weight
• Healthy Obesity, Metabolically
• Obesity
• Obesity, Metabolically Benign
• Physical Activity
• Weight Loss

Intervention

Behavioral:
• Lifestyle modification

Locations

Country	Name	City	State
Finland	Oulu Deaconess Institute Foundation sr	Oulu

Sponsors (3)

Lead Sponsor	Collaborator
University of Oulu	Oulu Deaconess Institute Foundation sr, Oulu University Hospital

Country where clinical trial is conducted

Finland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Weight change	Kilograms	Change from baseline weight at 36 months
Secondary	Waist circumference change	Cm	Change from baseline waist circumference at 36 months