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Neurobehavioral Manifestations clinical trials

View clinical trials related to Neurobehavioral Manifestations.

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NCT ID: NCT06239740 Completed - Clinical trials for Cognitive Dysfunction

Effects of Electroacupuncture on Cognitive Symptoms in Major Depressive Disorder

ELECACU-COG-Pi
Start date: December 24, 2022
Phase: N/A
Study type: Interventional

The goal of this pilot Study and Randomized Controlled Trial is to investigate the impact of electroacupuncture on cognitive function, quality of life (QoL), and depression severity in patients with major depressive disorder (MDD). The main question[s] it aims to answer are: - Primary : electroacupuncture has the potential to treat subjective cognitive complaints and cognitive impairment in MDD outpatients - Secondary : electroacupuncture has the potential to treat depressive in MDD outpatients The 60 participants will randomly be assigned to either the treatment group or the control group in a 1:1 ratio. The treatment group will undergo electroacupuncture (EA), while the control group will receive sham acupuncture within 10 weeks period. Both groups will receive antidepressants with adjunctive medication (i.e., benzodiazepines, tricyclics, or antipsychotics) as the standard treatment. All participants will be assessed for executive functions and memory using specific cognitive tests, including the Trail Making Test B (TMT-B), Stroop Color and Word Test (SCWT), category delayed recall in the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog), and subjective reports of concern regarding concentration, memory, problem-solving, learning, communication, and quality of life (QoL) concerns using the WHO Disability Assessment Schedule (WHODAS 2.0; sections D1.1-1.6 and H1-3), and depressive symptoms were assessed using the Thai-PHQ-9.

NCT ID: NCT05793736 Completed - Pain Clinical Trials

Prevention of Long Covid Syndrome

Start date: February 2, 2023
Phase: N/A
Study type: Interventional

Biofeedback equipment is classified by the Food and Drug Administration (FDA) as medical device class II and this type of equipment/treatment has shown evidence regarding stress management in post-Covid-19 syndrome. The main objective of the study is to verify the feasibility of an HVR biofeedback training protocol in patients with long covid, and also to verify improvement induced by the technique in relation to: cognitive performance; pain perception; fatigue; quality of life; depressive and anxious symptoms

NCT ID: NCT05523076 Completed - Clinical trials for Major Depressive Disorder

Transdiagnostic Markers of Cognitive Symptoms in Disorders Affective.

Start date: March 15, 2018
Phase:
Study type: Observational

The objective of this project is to determine the concordance between the subjective and objective evaluation of cognitive functions in affective patients in partial remission through scales and cognitive tests that would be easily implemented in the different mental health care devices. This is a cross-sectional case-control study of non-probabilistic sampling, which will include a group of patients diagnosed with Major Depressive Disorder and Bipolar Disorder and a group of healthy controls from the same population and matched by age, gender and years of education with the group of patients. Patients will be recruited from the psychiatric service of the Hospital de la Santa Creu i Sant Pau who meet the inclusion criteria, and they will undergo a blood draw, a clinical assessment, a complete neuropsychological examination together with scales of subjective perception of cognitive deficit, a measure of cognitive reserve and an evaluation of psychosocial functionality. In addition, the same evaluation will be made to a group of healthy subjects.The total sample will be 120

NCT ID: NCT04873804 Completed - Healthy Clinical Trials

The Effect of Transcranial Direct Stimulation on Cognitive Functions of Healthy Adults

Start date: October 10, 2019
Phase: N/A
Study type: Interventional

Background: Transcranial direct current stimulation(tDCS) has been used to improve cognitive functions in healthy young adults. Purpose: To investigate the effect of TDCS application on different cortex regions on cognitive function. Methods: Sixty individuals aged 18-30 were included in the study. The participants were randomly divided into the left dorsolateral prefrontal cortex (Left DLPFC Group)(n=20), the right posterior parietal cortex (Right PPC Group)(n=20), and the sham group (Sham Group)(n=20). tDCS was applied for 20 minutes on weekdays for 2 weeks. The participants were evaluated in terms of cognitive functions with Neuropsychometric Test Battery before and after treatment.

NCT ID: NCT04813965 Completed - Breast Cancer Clinical Trials

Breast Cancer Patients' Cognitive Symptoms After Information About Chemotherapy-Related Cognitive Symptoms

CONTEXT
Start date: March 20, 2014
Phase: N/A
Study type: Interventional

Previous cross-sectional studies have shown that informing cancer patients about potential chemotherapy-related cognitive symptoms may negatively affect perceived cognitive symptoms and verbal memory performance. A multicenter, randomized study in newly diagnosed breast cancer patients receiving (neo) adjuvant chemotherapy was performed to evaluate this Adverse Information Effect (AIE) over time and investigated whether inviting patients to self-affirm can reduce such AIEs on perceived cognitive symptoms and cognitive test performance.

NCT ID: NCT04809974 Completed - Covid19 Clinical Trials

Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19 Illness (Long-COVID)

Start date: July 22, 2021
Phase: Phase 4
Study type: Interventional

The study will assess whether Niagen, a safe dietary supplement, improves recovery of COVID-19 related symptoms in individuals who were infected at least 2 months prior to study entry ("Long-COVID" "Long-haulers"). 60% of participants will receive Niagen and 40% will receive PBO. Outcomes will consist of standardized cognitive, neuropsychiatric, physical, functional and biomarker assessments.

NCT ID: NCT04655079 Completed - Clinical trials for Progressive Supranuclear Palsy

Efficacy and Safety of Transcranial dIrect Current stiMulation (tDCS) in Progressive Supranuclear Palsy (PSP) (STIM-PSP)

STIM-PSP
Start date: February 1, 2021
Phase: N/A
Study type: Interventional

This is a double-blind, randomized, sham-controlled clinical trial that aim to verify the safety and the efficacy of anodal transcranial direct current stimulation (tDCS) on cognitive and motor symptoms in Progressive Supranuclear Palsy (PSP) over the left dorsolateral prefrontal cortex (dlPFC).

NCT ID: NCT04499560 Completed - Inflammation Clinical Trials

The Effects of a Nutrition Supplement on Health Related Quality of Life

Start date: August 3, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the health related benefits of a superfoods nutrition supplement on health related quality of life.

NCT ID: NCT04246736 Completed - Insomnia Clinical Trials

A Proactive Intervention Promoting Strategies for Sleep and Recovery in Nurses

Start date: January 30, 2017
Phase: N/A
Study type: Interventional

Considering the known challenges facing newly graduated nurses, there are possibilities to implement preventive actions. The aim of the current study was to evaluate the effects of a preventive intervention among newly graduated nurses, supporting proactive strategies for sleep and recuperation in relation to work related stress and shift work.

NCT ID: NCT04118985 Completed - Alzheimer Disease Clinical Trials

Compensatory Training to Support Brain Healthy Lifestyle Changes in Those at Risk for Alzheimer's Disease

Start date: October 10, 2019
Phase: N/A
Study type: Interventional

The Researchers are trying to better understand if behavioral interventions can help improve memory compensation and engagement in healthy lifestyle behaviors in those with memory concerns but normal mental status exam.