Myocardial Infarction Clinical Trial
— CovCardioVascOfficial title:
Cardiovascular Complications in Patients With COVID-19
Patients with COVID-19 in the Intensive Care Unit (ICU) or hospitalized with severe form have a poor prognosis (almost 30% rate of death). They present often a high cardiovascular risk profile (almost 30% of hypertension and 19% of diabetes). Troponin has been described to be elevated in a high proportion of patients (one fifth of all patients and 50% of non-survivors) suggesting the possibility of cardiomyopathies. High levels of DDimers (81% of non survivors) and fibrin degradation products are also associated with increased risk of mortality suggesting also the possibility of venous thromboembolism. Therefore, screening for cardiomyopathies and venous thromboembolism could represent an important challenge for patients with COVID-19 management.
Status | Recruiting |
Enrollment | 100 |
Est. completion date | August 31, 2021 |
Est. primary completion date | August 31, 2021 |
Accepts healthy volunteers | |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - All consecutive patients with COVID-19 infection admitted to the ICU or hospitalized because of severe form (eg: hypoxia, orthopnea, pneumonitis, kidney insufficiency) will be included Exclusion Criteria: - Patients under 18 years |
Country | Name | City | State |
---|---|---|---|
France | Centre Hospitalier de Cannes | Cannes | |
France | CHU de Dijon | Dijon | |
France | Centre Hospitalier de Draguignan | Draguignan | |
France | Centre Hospitalier de Grasse | Grasse | |
France | Clinique Ambroise-Paré | Neuilly | |
France | CHU de Nice | Nice | |
France | Hôpitaux Universitaires Paris Centre - Hôpital Cochin | Paris | |
France | CHU de REIMS | Reims |
Lead Sponsor | Collaborator |
---|---|
Centre Hospitalier Universitaire de Nice |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Determine the incidence of cardiomyopathies and venous thromboembolism | Incidence of cardiomyopathies and/or venous thromboembolism at day 28 | 28 days | |
Secondary | Mortality | Incidence of mortality at day 28 | 28 days | |
Secondary | Duration of mechanical ventilation | Number of day of using mechanical ventilation for each patients | hospitalisation duration | |
Secondary | Shock | Incidence of shock during hospitalisation | hospitalisation duration | |
Secondary | length of stay | Number of day at hospital | hospitalisation duration | |
Secondary | Mechanical ventilation | Setting up or not of mechanical ventilation | hospitalisation duration | |
Secondary | Renal replacement therapy | Administration or not of renal replacement therapy | hospitalisation duration |
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