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Thrombosis clinical trials

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NCT ID: NCT03575364 Not yet recruiting - DVT Clinical Trials

ClotTriever Outcomes (CLOUT) Registry

Start date: July 1, 2018
Phase:
Study type: Observational [Patient Registry]

Evaluate real world patient outcomes after treatment of acute and non-acute lower extremity deep vein thrombosis (DVT) with the ClotTriever Thrombectomy System.

NCT ID: NCT03573492 Recruiting - Pulmonary Embolism Clinical Trials

Bedside Ultrasound in the Assessment of Deep Venous Thrombosis: Effectiveness of In-Person Versus Online Instruction

Start date: June 4, 2018
Phase: N/A
Study type: Interventional

This study will examine the effectiveness of pre-recorded instructional videos in the use of bedside ultrasonography to ascertain the presence of a lower extremity deep venous thrombosis (DVT) as compared to in-person lectures and hands-on training.

NCT ID: NCT03571763 Not yet recruiting - Ischemic Stroke Clinical Trials

The Impact of Anti-thrombosis on Cerebral Microbleeds and Intracranial Hemorrhage in Ischemic Stroke Patients

Start date: June 2018
Phase:
Study type: Observational

The purpose of this prospective cohort study is to investigate whether antithrombotic therapy in the secondary prevention of ischemic stroke increases the risk of the emerging CMBs and whether the change is associated with an increased risk of intracranial hemorrhage, providing an imaging evidence for individualized antithrombotic therapy in such patients.

NCT ID: NCT03568890 Not yet recruiting - Stroke Clinical Trials

Short-Term Anticoagulation Versus Antiplatelet Therapy for Preventing Device Thrombosis Following Left Atrial Appendage Closure

ANDES
Start date: September 1, 2018
Phase: Phase 4
Study type: Interventional

The objective of the study is to compare short-term (8 weeks) anticoagulation therapy (DOAC) vs. antiplatelet therapy for the prevention of device thrombosis following transcatheter LAAC.

NCT ID: NCT03563924 Not yet recruiting - Cancer Clinical Trials

Allo - Cancer - Thrombosis

AlloTC
Start date: June 2018
Phase:
Study type: Observational

Management of venous thromboembolism (VTE) in patients with cancer is complex and require the intervention of many specialized health professionals, in hospital but also at home and during follow-up. The AlloTC project aims to integrate the management of VTE within the multidisciplinary care pathway of the patient with cancer, in order to improve the management of VTE in patients with cancer: optimize treatments and follow-up with appropriate anticoagulants, monitor the implementation of good clinical practice, promote patient involvement and adherence. The objective of this monocentric study is to evaluate the efficiency of the integration of the therapeutic management of VTE into a specific management of patient with cancer and to set up a specialized "AlloTC" team that coordinates this course of care. For that purpose, the management of VTE and outcome of patients with cancer and VTE will be compared between two periods : traditional management and management with the "AlloTC" team.

NCT ID: NCT03560219 Not yet recruiting - Stroke Clinical Trials

Association of Genetic Polymorphisms With Atrial Fibrosis and Thrombogenic Substrate in Patients With Non-valvular Atrial Fibrillation

ANATOLI-AF
Start date: July 1, 2018
Phase:
Study type: Observational

Atrial fibrillation (AF) is the most frequently encountered cardiac arrhythmia. Emerging data suggests that common genetic variants are associated with the development of AF. The main feature of the structural remodelling in AF is atrial fibrosis and is considered the substrate for AF perpetuation. Genome-wide association studies suggest that AF-susceptibility variants may modulate atrial fibrosis. However, the association between atrial fibrosis and genetic polymorphisms in humans has not yet been specifically investigated. In this study, we plan to investigate the relationship between genetic polymorphisms, atrial fibrosis and other components of thrombogenic substrate in patients with non-valvular AF. Primary objectives of this study are to assess associations between (i) polymorphic genetic variants and atrial fibrosis (detected by magnetic resonance imaging), (ii) polymorphic genetic variants and components of thrombogenic substrate (inflammation, endothelial function, prothrombotic state, atrial functions).

NCT ID: NCT03555552 Not yet recruiting - Clinical trials for Anticoagulation and Thrombosis Point of Care Test (AT-POCT)

Point of Care Testing to Improve Monitoring of LVAD Patients

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to develop and validate the accuracy of a low-cost "point-of-care" test (POCT) that allows monitoring of markers for anticoagulation and thrombosis (local coagulation or clotting of the blood), to be used by patients with advanced heart failure (AHF) on left ventricular assist device (LVAD) support. The investigators central hypothesis is that the fully-printed AT-POCT utilizing low-cost (printed) cassettes and detector will produce an inexpensive and convenient option for daily self-monitoring of PT/INR and LDH over existing methods.

NCT ID: NCT03547921 Not yet recruiting - Clinical trials for Paget Schroetter Syndrome

Primary Upper Limb Deep Vein Thrombosis. Is First Rib Resection Necessary?

Start date: July 1, 2018
Phase:
Study type: Observational

The purpose of the study is to compare outcome of patients with effort thrombosis who were treated operatively to those treated nonoperatively

NCT ID: NCT03544294 Completed - Stent Thrombosis Clinical Trials

veRy Thin Stents for Patients With Left mAIn or bifurcatioN in Real Life: the RAIN a Multicenter Study

RAIN
Start date: June 1, 2017
Phase:
Study type: Observational [Patient Registry]

For permanent coronary stents, reduction of thickness of struts have become one of the most important innovation, being related to easier manipulation, reduced risk of stent thrombosis and low rate of revascularization. Consequently the investigators performed a multicenter registry enrolling all consecutive patients treated with very thin stents for ULM or bifurcation.

NCT ID: NCT03541057 Recruiting - Clinical trials for Portal Vein Thrombosis

Vienna Vascular Liver Disease Study

VALID
Start date: December 12, 2017
Phase:
Study type: Observational [Patient Registry]

The aim of this Register Trial is to systematically study the epidemiology, risk factors, liver function as well prognosis of patients with vascular liver diseases. Furthermore, important clinical parameters will be assessed in order to evaluate patients' coagulation status and in order to develop new biomarkers derived from blood, urine, stool or ascites of patients as well as histological samples from the upper / lower GI-tract or the liver in order to better understand the natural history of vascular liver diseases.