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Metabolic Syndrome clinical trials

View clinical trials related to Metabolic Syndrome.

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NCT ID: NCT03921086 Active, not recruiting - Hypertension Clinical Trials

Hypertension And Surgery Study 2: A Multicentre, Cross-sectional Quality Improvement Project

HASS-2
Start date: January 14, 2019
Phase: N/A
Study type: Interventional

HASS-2 is a multi-center, cross-sectional quality improvement project: evaluating the implementation of a hypertension guideline protocol by perioperative clinicians, as a model for improving various aspects of public health. The study will also describe the co-morbid risk profile of these newly identified or poorly controlled hypertensive patients. In addition, as a sub-study, these patients will be followed up at monthly intervals for 3 months after discharge, in order to quantify the rates of compliance with their prescribed treatment.

NCT ID: NCT03853343 Active, not recruiting - Metabolic Syndrome Clinical Trials

Seaweed Extract Supplementation and Metabolic Biomarkers

Start date: June 28, 2018
Phase: N/A
Study type: Interventional

Double blinded, randomized, placebo controlled preliminary pilot exploratory investigation into the effects of brown seaweed extract supplementation, on fasting blood Insulin, fasting blood glucose, insulin sensitivity, blood inflammatory markers and tolerance in healthy overweight adults.

NCT ID: NCT03749200 Active, not recruiting - Metabolic Syndrome Clinical Trials

Motivational Approach to Treat Childhood Obesity

OBEMAT20
Start date: January 1, 2016
Phase: N/A
Study type: Interventional

The treatment of childhood obesity is challenging. Although dietary and physical activity recommendations are widely known, the willingness to change lifestyles within the family is not easy to be achieved. Motivational interviewing has been shown as a possibly effective method to increase adherence to dietary recommendations in the obese adult. There is scarce evidence showing whether implementing a motivational interview in obese children could be effective. The aim of this clinical trial is assessing the effect of a motivational interview, coordinated between the clinical and primary care services on 8 to 14 years old obese children.

NCT ID: NCT03534037 Active, not recruiting - Metabolic Syndrome Clinical Trials

Urate Lowering Therapies and Left Ventricular Diastolic Dysfunction

Start date: December 3, 2018
Phase: Phase 4
Study type: Interventional

Hyperuricemia is an additional risk factor for cardiovascular disease, associating with left ventricular diastolic dysfunction in individuals with metabolic syndrome. The effect of urate-lowering therapies on left ventricular diastolic dysfunction remains unclear. The study is conducted to investigate whether febuxostat or benzbromarone might improve left ventricular diastolic dysfunction in individuals with metabolic syndrome and hyperuricemia

NCT ID: NCT03520556 Active, not recruiting - Obesity Clinical Trials

Systematic Review and Meta-analysis of the Differential Effects of DHA and EPA on Inflammation

Start date: April 16, 2018
Phase:
Study type: Observational

According to the World Health Organization, cardiovascular diseases (CVDs) are the number 1 cause of death globally. Systemic and local tissue inflammation is now recognized as a key etiological process leading to CVD. Hence, elevated blood levels of inflammation markers are classified among the well-established risk factors for the development of CVD. Among nutritional strategies to prevent and/or reduce chronic inflammation, long-chain omega 3 PUFA (LCn-3PUFA), notably eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have raised tremendous interest for their purported anti-inflammatory effects. Previous meta-analysis of randomized controlled trials (RCTs) substantiated the anti-inflammatory effect of LCn-3PUFA supplementation as evidenced by significant reductions in plasma concentrations of specific inflammation markers such as C-reactive protein (CRP) and tumor necrosis factor alpha (TNF-alpha). However, it is stressed that almost all of the reported RCTs have used a mix of EPA and DHA in various ratios, as EPA and DHA occur concomitantly and naturally in food (fish oils) and in most dietary supplements. Yet, several recent RCTs have recently been undertaken to test the hypothesis that not all LCn-3PUFAs are equal, at least when it comes to their anti-inflammatory effects. Accordingly, there is increasing interest and evidence for potential distinctive effects of DHA compared to EPA on systemic inflammation, raising the question: Is DHA a more potent anti-inflammatory nutrient than EPA? To formally answer this question, we will conduct a systematic review and meta-analysis of RCTs to assess and compare the individual anti-inflammatory effects of DHA and of EPA. The present work will be a pairwise and network meta-analysis focusing on RCTs comparing the effects of EPA and DHA on surrogate markers of systemic inflammation. The findings generated by these analyses will provide invaluable and timely comparative information on the specific efficacy of DHA and EPA as one of the key nutritional modalities for the treatment of chronic inflammation in high-risk men and women. This is important considering that LCn-3PUFA supplements are increasingly being used by the population and an ever growing market in the dietary supplements' industry.

NCT ID: NCT03490747 Active, not recruiting - Obesity Clinical Trials

Evaluation of a Physical Activity Referral Scheme

Start date: March 12, 2018
Phase: N/A
Study type: Interventional

The study will evaluate the effectiveness of a co-developed exercise referral scheme. Participants will be recruited to one of three groups 1. Co-developed exercise referral scheme, 2. Usual care exercise referral scheme, 3. No treatment control (no intervention). The study will measure effectiveness by observing change in cardiorespiratory fitness at 12 weeks. Intervention cost-effectiveness will also be evaluated at 3 months follow-up using objective physical activity data.

NCT ID: NCT03448185 Active, not recruiting - Obesity Clinical Trials

Improving Metabolic Health in Patients With Diastolic Dysfunction

MTG
Start date: June 1, 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether 1 year of supervised exercise training in obese individuals at high risk for developing HF, incorporating high intensity interval training (HIIT) two to three times per week in conjunction with daily oral administration of omega-3 poly-unsaturated fatty acids will lead to reduction in visceral adiposity, regression of myocardial triglyceride levels and improvements in cardiac diastolic and vascular function.

NCT ID: NCT03352063 Active, not recruiting - Metabolic Syndrome Clinical Trials

Prolonged Sitting on Responses to Short-Term Exercise Training

Start date: July 17, 2018
Phase: N/A
Study type: Interventional

Prolonged sitting has been shown to effect the response to a high fat tolerance test (HFTT) after acute exercise. This study will evaluate the effect of prolonged sitting on response to a HFTT after a short term training period.

NCT ID: NCT03297749 Active, not recruiting - Metabolic Syndrome Clinical Trials

Genetic Variants and Oxidative Stress as Links Between Periodontitis and Metabolic Syndrome

Start date: July 1, 2015
Phase: N/A
Study type: Observational

The aim of this study is to investigate the systemic impact of periodontitis in patients with Metabolic Syndrome, by assessing measures of sub-clinical atherosclerosis and cardiovascular risk, microbial factors and host genetic variants, and to study the possible effect of mediators of inflammation and oxidative stress as links between the two conditions.

NCT ID: NCT03293264 Active, not recruiting - Metabolic Syndrome Clinical Trials

Exercise Training on Metabolic Syndrome Severity in Employees

Start date: October 17, 2017
Phase: N/A
Study type: Interventional

Hypothesis: An occupational 6 months physical exercise training will lead to better health behaviour and improve the severity of the metabolic syndrome. 300 subjects will be assigned to either an intervention or a waiting-control-group. The intervention group will receive instructions with the aim to perform 150 min exercise training per week. Exercise consists of endurance, strength and coordination training. A feedback system guided by sports scientists will be installed for all subjects in the intervention group using activity monitoring (wearable). After 6 months training subjects from the intervention group will be assigned to one of the following groups for follow-up observation from month 6 to months 12: - training with personal/individual feedback from sport scientist - training with automated feedback using activity monitoring Tools (wearable) - training without further feedback Subjects assigned to the control group will be provided with information on low intensity motion exercises. After 6 months in the control group subjects will be provided with the same exercise intervention as the intervention for a duration of 6 months. Study visits will be conducted at month 0, month 6 and month 12.