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Clinical Trial Summary

Major depressive disorder (MDD) is a prevalent mental illness characterised by influencing the health and quality of life of patients,often manifesting in individuals under the age of 18. It has been wildly confirmed that acupuncture alone or in combination with the applicable adjuvant therapy for MDD can not only relieve patients' physical symptoms, but also enhance sleep quality. Intradermal acupuncture, as an acceptable and long-lasting treatment modality, is the focus of this research. This study was conducted to investigate the efficacy of intradermal acupuncture in the treatment of MDD.


Clinical Trial Description

This study will enroll a total of 120 adolescents with MDD who meet the inclusion criteria. Participants will be randomly assigned 1:1:1 to the waiting list group (patients in this group will be treated with selective 5-hydroxytryptamine reuptake inhibitors (SSRIs) only), sham intradermal acupuncture combined with SSRIs (SIA) group and active intradermal acupuncture combined with SSRIs (AIA) group. The study is aim to evaluate the efficacy of intradermal acupuncture for MDD and examine whether intradermal acupuncture reduces side effects and improves the efficacy of SSRIs for MDD. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05832619
Study type Interventional
Source The Third Affiliated hospital of Zhejiang Chinese Medical University
Contact Xiaomei Shao, Ph.D
Phone +8618957130287
Email shaoxiaomei@zcmu.edu.cn
Status Recruiting
Phase N/A
Start date November 1, 2022
Completion date December 30, 2025

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