Intradermal Needle Therapy for Major Depressive Disorder

Status Not yet recruiting

Clinical Trial Summary

Major depressive disorder (MDD) is a common mental disorder that affects patients' physical health and quality of life. Although traditional acupuncture therapy has certain advantages in improving MDD, there are still some limitations, such as being time-consuming and some people having a fear of acupuncture. Therefore, intradermal needle therapy will be chosen in the treatment of MDD in this study, which is more convenient, shallow needling, and gentle than traditional acupuncture therapy. The study is designed to investigate the therapeutic effect and safety of intradermal needles for MDD.

Clinical Trial Description

A total of 120 participants with MDD who meet the inclusion criteria will be included in the study. Participants will be randomly divided into the SSRIs + acupuncture group, acupuncture + placebo group, and SSRIs + sham acupuncture group. This study will evaluate the efficacy and safety of the intradermal needle for MDD and investigate whether the intradermal needle reduces side effects and increases the efficacy of selective serotonin reuptake inhibitors (SSRIs) antidepressants for MDD. Furthermore, the study will demonstrate whether the intradermal needle has a synergistic effect with SSRIs on the treatment of MDD. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05352113
Study type	Interventional
Source	The Third Affiliated hospital of Zhejiang Chinese Medical University
Contact	Xiaomei M Shao, Ph.D
Phone	+8618957130287
Email	shaoxiaomei@zcmu.edu.cn
Status	Not yet recruiting
Phase	N/A
Start date	May 1, 2022
Completion date	December 30, 2025

View Details

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