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Clinical Trial Summary

The Wellness Monitoring for Major Depressive Disorder (MDD) study is a prospective, longitudinal, observational study aimed at identifying biomarkers of relapse in MDD. Results may help refine clinical approach to relapse management, and may ultimately help MDD patients sustain wellness while on antidepressant medication.


Clinical Trial Description

This study involves a naturalistic follow up of responders from the study entitled "Integrated biological markers for the prediction of treatment response in depression", or the CAN-BIND-1 study. In addition, this study is also open to other participants who completed other CAN-BIND studies, as well as remitters who meet the inclusion criteria. Since patients usually seek medical attention only after relapse has occurred, imminent precursors to relapse are not well known. In this study, participants who are currently responding to an oral antidepressant treatment regimen and/or therapeutic intervention will be monitored over a minimum period of 13 months, which provides a unique opportunity to discover near-term biomarkers of relapse. The study is conducted in partnership with Janssen Research & Development and utilizes remote monitoring technology for data gathering. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02934334
Study type Observational
Source University Health Network, Toronto
Contact
Status Completed
Phase
Start date May 31, 2016
Completion date February 25, 2019

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