Major Depressive Disorder Clinical Trial
Official title:
Adapting Marital Therapy in Older Adults With Depression
The primary goal of this study is to develop and test a depression-specific marital therapy tailored for use with older adult populations.
Major depression has been associated with many individual and interpersonal problems in
later life, including inadequate social support, marital distress, spousal depression, poor
physical health, and higher rates of mortality. Marital therapy has shown promise as a
treatment for depression and coexisting marital distress in younger cohorts, and there is a
robust association between social support and depressive symptoms in older adults. The
combination of couple therapy and antidepressant medication may provide an ideal treatment
for older adults by targeting interpersonal and biochemical aspects of depression.
Couples interested in this study will complete an initial assessment with study personnel.
In Phase I, eligible couples will receive weekly marital therapy and the depressed partner
will receive medication management with a study doctor for 6 months. In Phase II, couples
will be randomly assigned to either the combination treatment (marital therapy plus
medication management) or medication management alone for 6 months. At the end of the
treatment phase, a thorough assessment will be completed. A follow-up assessment will be
completed 6 months after completion of treatment.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
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