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Lung Diseases clinical trials

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NCT ID: NCT00599079 Completed - Clinical trials for Mycobacterium Avium Complex Lung Disease

Azithromycin in the Treatment of M. Avium Complex Lung Disease

Start date: February 1993
Phase: Phase 4
Study type: Interventional

To determine the safety and efficacy of azithromycin in the treatment of lung infection with M.avium complex and M. abscessus lung disease.

NCT ID: NCT00598962 Completed - Clinical trials for Mycobacterium Avium Complex

Use of Azithromycin and Rifabutin Administered 3 Times Weekly for the Treatment of M. Avium Complex (MAC) Lung Disease

Start date: December 1994
Phase: Phase 4
Study type: Interventional

To determine the safety and efficacy of azithromycin, rifabutin and ethambutol given three times weekly in the treatment of lung infection with M. avium complex(MAC)

NCT ID: NCT00598897 Completed - Clinical trials for Mycobacterium Avium Complex Lung Disease

Use of Clarithromycin and Rifabutin for the Treatment of M. Avium Complex (MAC) Lung Disease

Start date: August 1995
Phase: Phase 4
Study type: Interventional

To determine the safety and tolerance of clarithromycin given three times per week in combination with multiple drugs including rifabutin three times per week

NCT ID: NCT00595114 Completed - Asthma Clinical Trials

Association Between Increased Oxidative Stress, Anti-Inflammatory Fatty Acid Formation, and Airway Infection in People With Asthma and Chronic Obstructive Pulmonary Disease

Start date: December 2007
Phase: Phase 0
Study type: Observational

Chronic obstructive pulmonary disease (COPD) and asthma are common respiratory diseases in which people experience long-term inflammation of the lungs. Exacerbations, or prolonged worsening of symptoms, of asthma and COPD are often life-threatening and can lead to frequent need for hospitalization. Even with the proper use of bronchodilators, corticosteroids, and other currently available medications, clinical responses among people with COPD and asthma are variable. There remains a significant unmet clinical need for new therapeutic approaches and insights, including the identification of biomarkers to accurately assess the presence of airway infection and intensity of airway inflammation. This study will investigate potential natural biological causes and new biomarkers for increased susceptibility to persistent airway infection in asthma and COPD.

NCT ID: NCT00594009 Terminated - Clinical trials for Pulmonary Disease, Chronic Obstructive

Venovenous CO2 Removal (VVCO2R) in Patients With COPD and Acute Respiratory Failure

VVCO2R
Start date: January 2008
Phase: N/A
Study type: Interventional

The purpose of this study to determine the safety and effectiveness of a mechanical device to remove carbon dioxide from the blood of patients with chronic obstructive pulmonary disease (COPD)when they are hospitalized in the intensive care unit for exacerbation of their condition.

NCT ID: NCT00583986 Completed - Asthma Clinical Trials

Reliability of a Top Mount Actuation Indicator With Levalbuterol MDI in Adult and Pediatric Subjects With Asthma or COPD

Start date: September 2005
Phase: Phase 3
Study type: Interventional

This is a study to investigate the reliability, ruggedness and safety of the top mounted actuation indicator (TMAI) when used with Levalbuterol HFA MDI.

NCT ID: NCT00581945 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Safety and Efficacy of Multiple Doses of Canakinumab (ACZ885) in Chronic Obstructive Pulmonary Disease (COPD) Patients

Start date: January 2007
Phase: Phase 1/Phase 2
Study type: Interventional

Was to evaluate the safety, tolerability and efficacy of multiple doses of canakinumab (ACZ885) vs. placebo when administered via intravenous infusion (IV), on pulmonary function in patients with COPD

NCT ID: NCT00579046 Withdrawn - Clinical trials for Chronic Obstructive Pulmonary Disease

Study of Erythropoietin to Treat Anemia Complicating Chronic Obstructive Pulmonary Disease

ELAB
Start date: November 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the impact of erythropoietin treatment of anemia on exercise capacity of patients with chronic obstructive pulmonary disease (COPD).

NCT ID: NCT00578968 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Cardiac Limitations in Chronic Obstructive Pulmonary Disease: Benefits of Bronchodilation

Start date: October 2006
Phase: Phase 4
Study type: Interventional

This study is being done to examine the influence of Tiotropium (good or bad) on heart function at rest and during exercise in patients with moderate to severe chronic obstructive pulmonary disease (COPD).

NCT ID: NCT00571428 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Efficacy Safety Study of Arformoterol QD Dosing Versus BID Dosing in COPD

Start date: November 2007
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy and safety of arformoterol tartrate inhalation solution 30μg/4mL QD (two 15μg/2mL dosed in combination) over a 24-hour period compared to arformoterol tartrate inhalation solution 15μg/2 mL BID in subjects with COPD.