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Lung Diseases clinical trials

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NCT ID: NCT00796653 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Safety and Efficacy of BI 1744 CL in Patients With Chronic Obstructive Pulmonary Disease II

Start date: January 2009
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to assess the long-term efficacy and safety of once daily treatment of BI 1744 CL inhalation solution (5 and 10 mcg) delivered via the Respimat® inhaler, in patients with COPD.

NCT ID: NCT00794157 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Confirmatory Study of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Start date: November 2008
Phase: Phase 3
Study type: Interventional

This study was designed to provide pivotal confirmation of efficacy and safety data for 2 doses of indacaterol (150 and 300 µg once daily [od]) in patients with moderate to severe chronic obstructive pulmonary disease (COPD). Data from this study will be used for the registration of indacaterol in Japan.

NCT ID: NCT00793624 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Safety and Efficacy of BI 1744 CL in Patients With Chronic Obstructive Pulmonary Disease I

Start date: February 2009
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to assess the long-term efficacy and safety of once daily treatment of BI 1744 CL inhalation solution (5 and 10 mcg) delivered via the Respimat® inhaler, in patients with COPD.

NCT ID: NCT00792974 Recruiting - Depression Clinical Trials

End-of-Life Fear in Patients With End-Stage Lung Disease (COPD)

Start date: October 2008
Phase: N/A
Study type: Observational

The aim of the study is to develop an interview to ask patients with COPD about their fear of death and dying, their needs and wishes at the end-of-life. Afterwards, the patients receive a brief psychological intervention to develop coping strategies for chronic illness. Beside this a general purpose of this intervention is to improve patients' quality of life.

NCT ID: NCT00792805 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Efficacy and Safety of Indacaterol in Adults (40 Years and Above) With Chronic Obstructive Pulmonary Disease (COPD)

Start date: November 2008
Phase: Phase 3
Study type: Interventional

This study evaluated the efficacy and safety of two doses of indacaterol in adults aged 40 or over with chronic obstructive pulmonary disease (COPD) in China and in two other countries.

NCT ID: NCT00791518 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Evaluation of Lung Function and Symptoms in Patients Diagnosed With Chronic Obstructive Pulmonary Disease (COPD) on Long-Acting Bronchodilator Monotherapy

LABD
Start date: December 2008
Phase: N/A
Study type: Observational

A multicenter study to evaluate lung function and symptoms in subjects with COPD who have been on regular use of only one long-acting bronchodilator.

NCT ID: NCT00791505 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Antibiotic/COPD in Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) Requiring Mechanical Ventilation

Start date: July 2002
Phase: Phase 3
Study type: Interventional

Although the use of antibiotics in the treatment of acute exacerbation of chronic obstructive pulmonary disease (COPD) is largely accepted, controversy remains regarding whether the choice of antibiotic has any impact on outcome. Our aim was to compare the effects of the combination of trimethoprim and sulfamethoxazole and ciprofloxacin in patients treated for severe COPD exacerbation requiring mechanical ventilation.

NCT ID: NCT00784550 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

A 24-Week Study to Evaluate the Safety and Efficacy of ADVAIR DISKUS 250/50mcg Plus SPIRIVA HANDIHALER Versus SPIRIVA HANDIHALER Plus Placebo DISKUS in Subjects With Chronic Obstructive Pulmonary Disease (COPD). SPIRIVA and HANDIHALER Are Trade Marks of Boehringer Ingelheim

ADC111114
Start date: December 2008
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine the efficacy and safety of the combination of ADVAIR DISKUS 250/50mcg (FLUTICASONE PROPIONATE/SALMETEROL COMBINATION PRODUCT) plus SPIRIVA HANDIHALER 18mcg (TIOTROPIUM)compared to SPIRIVA HANDIHALER 18mcg (TIOTROPIUM) in patients with COPD.

NCT ID: NCT00784329 Withdrawn - Lung Cancer Clinical Trials

Pilot Study To Evaluate Optical Frequency Domain Imaging For Diagnosis Of Central Airway Disease

Start date: March 2008
Phase: N/A
Study type: Interventional

To evaluate the potential of a new imaging device, termed Optical Frequency Domain Imaging (OFDI), in the early diagnosing of pulmonary malignancies in the central airways.

NCT ID: NCT00783978 Completed - Clinical trials for Chronic Lung Disease

Surfactant Disorders and Chronic Lung Disease

APSE
Start date: September 2009
Phase: N/A
Study type: Observational

Interstitial lung diseases (ILD) in children represent a heterogeneous group of rare and not well defined disorders. Genetic abnormalities of surfactant proteins B (SFTPB) and more recently C (SFTPC) have been shown to be related to these pathologies. However, variability in the lung disease phenotype suggests the involvement of other surfactant-associated genes such as ABCA3 (ATP-binding cassette, sub-family A, member, 3). Thus, the aim of this project is: 1) to assess the prevalence of SFTPC mutation in children with chronic lung diseases, 2) to precise clinical and radiological features of children with SFTPC mutation, and 3) to identify environmental or genetic factors that may explain the extreme variability of this disease.