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Lung Diseases clinical trials

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NCT ID: NCT01933984 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Individualized Dosing Schedule of Inhaled Bronchodilator for Endotracheally Intubated COPD Patients

Start date: August 2013
Phase: N/A
Study type: Interventional

This study evaluates whether individualized dosing schedule of inhaled bronchodilator is more effective than fixed dosing in reducing airway resistance of intubated COPD patients.

NCT ID: NCT01933789 Completed - Heart Failure Clinical Trials

Improving Communication About Serious Illness

ICSI
Start date: September 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to improve care delivered to patients with serious illness by enhancing communication among patients, families, and clinicians in the outpatient setting. We are testing a new way to help patients share their preferences for talking about end-of-life care with their clinicians and families. To do this we created a simple, short feedback form. The form is designed to help clinicians understand what patients would like to talk about. The goal of this research study is to show that using a feedback form is possible and can be helpful for patients and their families.

NCT ID: NCT01933334 Completed - Systemic Sclerosis Clinical Trials

Safety and Tolerability of Pirfenidone in Patients With Systemic Sclerosis−Related Interstitial Lung Disease (SSc-ILD) (LOTUSS)

Start date: September 2013
Phase: Phase 2
Study type: Interventional

PSSc-001 (LOTUSS) This study is a Phase 2, multinational, open-label, randomized, parallel-group, safety and tolerability study of pirfenidone in patients with systemic sclerosis−related interstitial lung disease (SSc-ILD).

NCT ID: NCT01931644 Completed - Breast Cancer Clinical Trials

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

Start date: July 2013
Phase:
Study type: Observational

We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research. We make it easy for patients to contribute to research for medical conditions that matter most to them, regardless of their location or ability to travel.

NCT ID: NCT01926275 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

NPPV Added Inspiratory Muscle Training in Severe COPD

Start date: July 2013
Phase: N/A
Study type: Interventional

The aim of this study is to determine whether noninvasive positive pressure ventilation with inspiratory muscle training can improve quality of life and respiratory muscle strength than noninvasive positive pressure ventilation or inspiratory muscle training alone.

NCT ID: NCT01923051 Active, not recruiting - Clinical trials for Chronic Obstructive Airway Disease

Czech Multicentre Research Database of Chronic Obstructive Pulmonary Disease (COPD)

Start date: August 2013
Phase:
Study type: Observational

The chronic obstructive pulmonary disease (COPD) is the occurrence of chronic bronchitis or emphysema, a pair of commonly co-existing diseases of the lungs in which the airways narrow over time. This limits airflow to and from the lungs, causing shortness of breath (dyspnoea). In clinical practice, COPD is defined by its characteristic airflow limitation on lung function tests. In contrast to asthma, this limitation is poorly reversible and usually gets increasingly worse over time. The COPD registry is a non-interventional multicentre observational prospective database focusing on the collection and analysis of data on real mortality and morbidity in COPD population of the Czech Republic population of COPD patients. Monitoring is done at the occasion of regular check-ups, followed by retrospective search of data in the documentation, and a record into the registry. The aim of Czech National Research Database of Chronic Obstructive Pulmonary Disease is to establish the clinical course of severe forms of COPD, establish the cause for deterioration of clinical status of our patients and describe the progression of COPD to death. The registry fulfils general objectives of health registries such as monitoring of causes, development, treatment and consequences of a severe disorder, including economic and social impacts. Statistical and scientific analyses of the registry data are focused, in particular, on the assessment of health determiners of the selected patient cohort with the aim to improve health status of the patients.

NCT ID: NCT01922271 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Efficacy of NVA237 Compared to Tiotropium in Patients With Chronic Obstructive Pulmonary Disease (COPD)

FAST
Start date: August 2013
Phase: Phase 4
Study type: Interventional

The purpose of this study is to further figure out differences of glycopyrronium bromide compared to tiotropium in early bronchodilation measured by a comprehensive assessment of lung function that includes hyperinflation and specific airway resistance in patients with moderate to severe COPD.

NCT ID: NCT01922180 Completed - COPD Exacerbation Clinical Trials

Chronic Obstructive Pulmonary Disease: CT Features of Severe Exacerbation

Start date: July 2007
Phase: N/A
Study type: Observational

To describe Computed Tomography (CT) features associated with severe exacerbations of Chronic Obstructive Pulmonary Disease (COPD).

NCT ID: NCT01921712 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

A Safety, Pharmacokinetic and Pharmacodynamic Study of PUR0200 in COPD Patients

Start date: July 2013
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of PUR0200. In addition, the study will look at the blood levels of different doses of PUR0200 and their affect on lung function in COPD patients.

NCT ID: NCT01921556 Active, not recruiting - COPD Clinical Trials

The Improving Care in Chronic Obstructive Lung Disease Study A Cluster Randomized Trial

CAROL
Start date: September 2013
Phase: N/A
Study type: Interventional

Background The Swiss health ministry launched a national quality program "QualiCCare" in 2011 to improve healthcare for patients with COPD. The aim of this study is to determine whether participation in the COPD quality initiative ("QualiCCare") improves adherence to recommended clinical processes and shows impact on patients COPD care and on quality of life in patients with COPD.