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Knee Arthroplasty, Total clinical trials

View clinical trials related to Knee Arthroplasty, Total.

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NCT ID: NCT06357013 Active, not recruiting - Pain, Postoperative Clinical Trials

Postoperative Analgesia in Bilateral Knee Arthroplasties

Start date: January 1, 2024
Phase:
Study type: Observational

To observationally compare the analgesic efficacy of LIA and S-FICB techniques and to record the pain scores of patients who underwent bilateral knee operations in the postoperative period.

NCT ID: NCT06180889 Recruiting - Clinical trials for Knee Arthroplasty, Total

Factor XI inhibiTion for the Prevention of Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty

Start date: December 20, 2023
Phase: Phase 2
Study type: Interventional

This study was to compare the study drug KN060 to enoxaparin, for the prevention of blood clotting and safety in patients undergoing total knee arthroplasty (TKA).

NCT ID: NCT06162208 Recruiting - Telerehabilitation Clinical Trials

Action Observation Therapy Via Telerehabilitation on Total Knee Arthroplasty Surgery

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare patient-reported and performance-based outcomes of patients followed with a standard exercise program based on telerehabilitation and patients followed with action observation therapy program added to a standard exercise program based on telerehabilitation after total knee arthroplasty surgery. The main questions it aims to answer are: - [What is the effect of action observation therapy added to a telerehabilitation-based standard exercise program on patient-reported outcomes after total knee arthroplasty surgery?] - [What is the effect of action observation therapy added to a telerehabilitation-based standardized exercise program on performance-based outcomes after total knee arthroplasty surgery?] Participants will be divided into three groups by computer-assisted randomization method: Group 1: home exercise with information leaflet group, Group 2: information leaflet + telerehabilitation-based standard exercise program group, Group 3: information leaflet + telerehabilitation-based standard exercise program + action observation therapy group. Patients in the second and third groups will be followed up with the telerehabilitation method accompanied by a physiotherapist for 30 minutes 3 days a week for 6 weeks after discharge. The third group will receive a standard exercise program 3 days a week and 15 minutes of action observation therapy via video conferencing.

NCT ID: NCT06108063 Recruiting - Clinical trials for Knee Arthroplasty, Total

Mitigation of Arthrofibrosis After Total Knee Arthroplasty Using Losartan

Start date: March 6, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy of Losartan use post-operatively for reducing or preventing the development of arthrofibrosis and the associated adverse impacts on clinical outcomes.

NCT ID: NCT05877261 Recruiting - Knee Osteoarthritis Clinical Trials

Cementless Triathlon 5YR Follow-Up

Start date: May 25, 2023
Phase:
Study type: Observational

All artificial joint implants need to be solidly held (fixed) within the bone. Cementless fixation has become a popular method to achieve fixation for total knee replacements where the bone grows directly onto the implanted device instead of using bone cement. The primary purpose of this study is to assess long-term implant survivorship and clinical outcomes of a previous study cohort that received a cementless knee replacement. As this study cohort approaches 5 years post-operation, the investigators will re-examine the stability of participant implants using specialized x-rays, called "radiostereometric analysis". The study will use weight-bearing computed tomography (CT) to measure bone density and texture features and correlate that with implant stability. The investigators will collect stool samples to assess participant gut microbiomes for biomarkers of poor bone quality that could correlate to implant stability. All 33 participants from the original study cohort will be invited to participate in this study.

NCT ID: NCT05788757 Recruiting - Clinical trials for Knee Arthroplasty, Total

Optetrak Knee System Post Market Clinical Follow-Up

Start date: June 1, 2011
Phase:
Study type: Observational

A Post-Market Domestic (US) and International Data Collection to Assess the Optetrak Knee System

NCT ID: NCT05653102 Recruiting - Clinical trials for Knee Arthroplasty, Total

A Post-Market Domestic (US) and International Data Collection to Assess the Truliant Knee System

Start date: January 23, 2019
Phase:
Study type: Observational

A Post-Market Domestic (US) and International Data Collection to Assess the Truliant® Knee System

NCT ID: NCT05516381 Recruiting - Clinical trials for Knee Arthroplasty, Total

Evaluation of Navigation-Assisted TKA Using Mechanical vs. Restricted Kinematic Alignment

Start date: May 15, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate both clinical measures and PROMs in patients undergoing total knee arthroplasty (TKA) using restricted inverse kinematic alignment (iKA) compared to mechanical alignment (MA), both using surgical navigation assistance.

NCT ID: NCT05100706 Recruiting - Acute Pain Clinical Trials

Continuous Adductor Canal Block in Outpatient Total Knee Arthroplasty

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

Total knee arthroplasty (TKA) is a frequent performed surgery. Many institutions are implementing outpatient programs for this surgery and adequate pain management is an important feature. Analgesic duration of single shot nerve blocks is limited to no more than 24h. Conversely, the use of continuous nerve block (CNB) through a perineural catheter and infusion of local anesthetic may increase duration of analgesia and provide better outcomes. The purpose of this study is to evaluate effectiveness and safety of using CNB in patients undergoing ambulatory TKA, and its effects on patients' quality of recovery. We hypothesize that continuous adductor canal block would lead to a better quality of recovery in patients undergoing outpatient TKA.

NCT ID: NCT04575246 Completed - Hypothermia Clinical Trials

Predictors and Outcomes of Intraoperative Hypothermia in Patients Undergoing Knee Arthroplasty

Start date: January 1, 2016
Phase:
Study type: Observational

The study is designed to retrospectively assess the risk factors associated with intra-operative hypothermia in patients undergoing total knee arthroplasty from January 2016 to December 2017 at Aga Khan University and also understand it's impact on post-operative outcomes.