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Knee Arthroplasty, Total clinical trials

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NCT ID: NCT04575246 Completed - Hypothermia Clinical Trials

Predictors and Outcomes of Intraoperative Hypothermia in Patients Undergoing Knee Arthroplasty

Start date: January 1, 2016
Phase:
Study type: Observational

The study is designed to retrospectively assess the risk factors associated with intra-operative hypothermia in patients undergoing total knee arthroplasty from January 2016 to December 2017 at Aga Khan University and also understand it's impact on post-operative outcomes.

NCT ID: NCT04564729 Recruiting - Analgesia Clinical Trials

Shared Decision Aid for Post-Total Knee Arthroplasty Opioid Prescribing

Start date: November 2, 2020
Phase: N/A
Study type: Interventional

This will be a randomized controlled clinical trial in patients who have undergone primary unilateral total knee arthroplasty at Brigham and Women's Faulkner Hospital, Brigham and Women's Hospital and University of Chicago Medical Center. Study subjects will receive either a shared decision aid (SDA) about pain management or standard of care at the time of discharge. The impact of the SDA on the number of leftover opioid pills on postoperative day 30 and average NRS pain score on postoperative day 7 will be assessed.

NCT ID: NCT04450485 Completed - Clinical trials for Knee Arthroplasty, Total

Surgical Approach in Fast Track Knee Arthroplasty

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

Nowadays, due to the demands to improve life and health conditions of osteoarthritis patients, more effective surgical treatment methods are needed to obtain satisfactory results when performing total knee arthroplasty (TKA). Fast-track surgical protocols are evidence based multidisciplinary approaches targeted on multimodal patient care and primarily focused on enhancing rapid functional recovery of the patients. These protocols recommend use of minimal invasive approaches for TKA patients to enhance rapid recovery. Although studies in the literature has been reported similar results in medial para-patellar approach (MPP) and minimal invasive approaches in long terms, better surgical outcomes in short term in favor of minimal invasive approaches also encouraged fast-track protocol builders to prefer minimal invasive approaches. However, this recommendation is not evidence based and there is no study comparing surgical outcomes between minimal invasive approaches and MPP approach in terms of pain, length of hospital stays and functional recovery in fast-track TKA patients. Therefore, we aimed to compare the effects of mini mid-vastus (MMV) and MPP approaches on postoperative clinical results (pain, quality of life, functional outcome, and length of hospital stay) in fast-track TKA patients, and to decide whether any additional achievements are obtained with MMV approach in this patient group.

NCT ID: NCT04226339 Recruiting - Clinical trials for Knee Arthroplasty, Total

Evaluation of Walking Analysis After a Total Knee Arthroplasty With Kinematic Alignment Versus Mechanical Alignment

KneeKG Sphere
Start date: September 7, 2020
Phase: N/A
Study type: Interventional

Total knee arthroplasty (TKA) is a treatment for advanced femoro-tibial osteoarthritis. This surgery is justified in case of significant discomfort and failure of medical treatment. The functional results of TKA are good with a recovery of 6 months - 1 year. Nevertheless, very few patients forget their prostheses. A United Kingdom study assessed patient satisfaction in a cohort of 10,000 patients more than one year after TKA: nearly 20% were not satisfied with their TKA. The knee is indeed a complex articulation that works differently in the three space plans. Current knee prostheses are trying to replicate this biomechanics and get as close as possible to the anatomy of a native knee. Bellemans et al. found in 250 asymptomatic patients 32% of men with a constitutional varus greater than 3 ° and 17% of women. Restoration of normal knee function can also be achieved by restoring a moderate constitutional deformity present preoperatively. The objective of the femorotibial alignment was dogmatically fixed at 180° (mechanical femorotibial alignment). In recent years, some surgical teams have attempted to reproduce the preoperative constitutional deformity in varus or valgus with the prosthesis. This femorotibial alignment is called kinematic alignment. This kinematic alignment has already been studied in several randomized studies and has demonstrated improved functional scores. However, these studies focused on specific TKA, which are posterior cruciate TKA, and the assessment was subjective through functional scores. In addition, these TKA were often made with patient specific instrumentation (PSI). Some studies have evaluated walking kinematics after TKA with kinematic alignment. But it was again TKA retaining the posterior cruciate ligament. The investigators would like to prospectively evaluate the restoration of the medially stabilized TKA walking kinematics (medial-stable TKA or ball in socket stability) implanted with a kinematic alignment compared to a mechanical alignment.

NCT ID: NCT04090125 Completed - Clinical trials for Knee Arthroplasty, Total

Improving Physical Activity and Gait Symmetry After Total Knee Arthroplasty

PAS-TKA
Start date: November 8, 2019
Phase: N/A
Study type: Interventional

The purpose of this pilot study is to examine the effectiveness of the Physical Activity and Symmetry (PAS) program, compared to an attention (ATT)control group, for patients with post-total knee arthroplasty (TKA). The investigators hypothesize that the PAS treatment will result in meaningful improvements in physical activity (PA) and joint loading symmetry compared to the ATT group.

NCT ID: NCT03898544 Completed - Clinical trials for Knee Arthroplasty, Total

Gait Kinematics After Primary Total Knee Arthroplasty (TKA) Versus Revision TKA

Stryker-KneeKG
Start date: March 18, 2019
Phase:
Study type: Observational

The functional outcomes after TKA are satisfying with a full recovery at 6 months - 1 year. Nevertheless, the revisions of TKA have often lower functional results than primary TKA with a long delay of recovery. The Stryker TKA present the same device for primary TKA and for revision. The aim of this study is to compare the gait kinematics at 6 months after primary Stryker TKA or Revision Stryker TKA to assess if the objective outcomes are similar with this device.

NCT ID: NCT03703206 Completed - Clinical trials for Knee Arthroplasty, Total

The Analgesic Efficacy of Protocol for Primary Total Knee Arthroplasty (TKA)

Start date: July 1, 2018
Phase: Phase 3
Study type: Interventional

This is a perspective, randomized, blinded study with a parallel design and an allocation ratio of 1 to 1 for the treatment groups to assess the analgesic efficacy of adding the iPACK (injection between the popliteal artery and the capsule of the knee) in addition to the adductor canal block (ACB) for Total Knee Arthoplasty patients (TKA).

NCT ID: NCT03695640 Recruiting - Postoperative Pain Clinical Trials

Effect of Magnesium Sulphate on Analgesia Following Knee Arthroplasty

Start date: November 1, 2018
Phase: Phase 4
Study type: Interventional

This study is designed to investigate the effect of magnesium sulfate added to levobupivacaine in continuous femoral nerve block following total knee arthroplasty.

NCT ID: NCT03622398 Completed - Clinical trials for Knee Arthroplasty, Total

Highly Cross-linked Polyethylene in Total Knee Arthroplasty

Start date: January 2006
Phase: Phase 4
Study type: Interventional

The aim of this study was to determine clinical and radiographic results after posterior cruciate-substituting total knee arthroplasties with highly cross-linked polyethylene in one knee and compression mold conventional polyethylene in the contralateral knee in the same patients.

NCT ID: NCT03492320 Completed - Clinical trials for Total Knee Replacement

Progression of Health Related Quality of Life of Patients Waiting for Total Knee Arthroplasty

TKA HRQoL
Start date: March 1, 2013
Phase:
Study type: Observational

To evaluate the progression on patients suffering from end stage OA whilst being on the waiting list for TKR