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Ischemia clinical trials

View clinical trials related to Ischemia.

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NCT ID: NCT05570968 Not yet recruiting - Clinical trials for Lower Limb Ischemia Critical

Outcomes of Endovascular Revascularization in CLTI in Patients Associated With Heel Ulcers

Start date: October 2022
Phase:
Study type: Observational

The aim of the current study is to assess outcomes of endovascular revascularization of patients with CLTI associated with heel ulcers and identify possible predictors of healing of these ulcers.

NCT ID: NCT05570019 Recruiting - Clinical trials for Peripheral Arterial Disease

Evaluation of Tissue Perfusion in Peripheral Arterial Disease (EVTI-PAD)

EVTI-PAD
Start date: October 1, 2022
Phase:
Study type: Observational

In this prospective single-center observational study, arterial perfusion in patients with lower limb peripheral arterial disease will be assessed with standard diagnostic tools (toe pressure, trans-cutaneous oxygen pressure, ankle-brachial index and fluorescence angiography) before and after standard revascularization procedures (open surgery and/or angioplasty).

NCT ID: NCT05569369 Not yet recruiting - Lower Limb Ischemia Clinical Trials

Endovascular Management of Combined Common Femoral and Superficial Femoral Arteries Lesions

Start date: November 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the technical feasibility, safety, and 1-year clinical efficacy of the endovascular treatment of patients with atherosclerotic common femoral artery (CFA) obstructions with associated superficial femoral artery lesions. Participants will undergo angioplasty with or without stenting of common femoral and superficial femoral arteries.

NCT ID: NCT05566600 Recruiting - Clinical trials for Chronic Heart Failure

Allogeneic iPSC-derived Cardiomyocyte Therapy in Patients With Worsening Ischemic Heart Failure

Start date: October 9, 2022
Phase: Early Phase 1
Study type: Interventional

This study is designed to evaluate the safety and efficacy of allogeneic induced pluripotent cell derived cardiomyocytes (iPSC-CMs) in treating patients with worsening ischemic heart failure undergoing coronary artery bypass graft surgery. After screening, iPSC-CMs will be administrated intramyocardially in consented and eligible patients undergoing open-chest CABG surgery and the estimated population size for the study will be 32 patients.

NCT ID: NCT05561088 Recruiting - Clinical trials for Acute Ischemic Stroke

Efficacy and Safety of Head Acupuncture After Mechanical Thrombectomy for Acute Ischemic Stroke

HEALTH
Start date: April 27, 2023
Phase: N/A
Study type: Interventional

To evaluate the efficacy and safety of head acupuncture combined with endovascular therapy for cerebral infarction compared with endovascular therapy alone

NCT ID: NCT05560672 Recruiting - Clinical trials for Ischemic Bowel Disease

Clinical Application and Mechanism of Cord Blood Mononuclear Cells in the Treatment of Ischemic Bowel Disease

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

Ischemic bowel disease, also known as ischemic bowel disease (IBD), is a type of disease that causes the blood supply to a certain intestinal segment to be reduced or stopped by various reasons such as hypovolemia, shock or recent abdominal surgery, resulting in insufficient blood supply to the intestinal wall, and causing a series of pathological changes in the intestine. Human umbilical cord blood mononuclear cells (HUCB-MNC) can be economically and conveniently isolated from human cord blood. The HUCB-MNC obtained from the isolation of human umbilical cord blood contains a variety of stem cells, such as hematopoietic stem cells, endothelial stem cells, etc. A number of previous studies have confirmed that HUCB-MNC can improve the occurrence of ischemic bowel disease through immunomodulatory and tissue repair. These characteristics make HUCB-MNC a cell with great potential to treat ischemic diseases.

NCT ID: NCT05560152 Not yet recruiting - Clinical trials for Ischemic Stroke, Acute

Analyzing the Pharmacodynamic Substances and the Effects of Yiqihuayu Decotion for Acute Ischemic Stroke (PHYSIS)

PHYSIS
Start date: September 25, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The main purposes of this trial are to analyze the pharmacodynamic substances and the effects of Yiqihuayu Decotion for acute ischemic stroke. The trial is a non-randomized, controlled clinical trial.

NCT ID: NCT05559307 Recruiting - Clinical trials for Ischemic Stroke, Acute

Analyzing the Pharmacodynamic Substances and the Effects of Xingnaojing for Mild-to-Severe Acute Ischemic Stroke

PUBLISH
Start date: August 16, 2022
Phase: Phase 4
Study type: Interventional

The main purposes of this trial are to analyze the pharmacodynamic substances and the effects of Xingnaojing for mild-to-severe acute ischemic stroke.

NCT ID: NCT05553613 Completed - Ischemic Stroke Clinical Trials

Ticagrelor Versus Clopidogrel in Ischemic Stroke

Start date: October 1, 2022
Phase: Phase 3
Study type: Interventional

Along with the current clinical trial, the efficacy and safety of 180 mg loading dose of ticagrelor administered within the first 24 hours of first-ever ischemic stroke compared to 300 mg clopidogrel were assessed through NIHSS, mRS, duration of hospital stay, and possible adverse effects.

NCT ID: NCT05553509 Recruiting - Clinical trials for Chronic Limb Threatening Ischemia

Clinical Outcomes Following Surgical Debridement of Diabetic Foot Infection With Borderline Vascularity

Start date: January 1, 2023
Phase:
Study type: Observational

Observe Timing to complete healing of wounds & Limb salvage in both cohorts those who are undergoing Debridement only and those who are undergoing Debridement plus PTA