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Ischemia clinical trials

View clinical trials related to Ischemia.

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NCT ID: NCT04985981 Suspended - Colorectal Cancer Clinical Trials

The Prediction of Anastomotic Insufficiency Risk After Colorectal Surgery (PANIC) Study

Start date: April 1, 2021
Phase:
Study type: Observational [Patient Registry]

The Prediction of Anastomotic Insufficiency risk after Colorectal surgery (PANIC) study aims to establish a machine-learning-based application that allows for accurate preoperative prediction of patients at risk for anastomotic insufficiency after colon and colorectal surgery.

NCT ID: NCT04984577 Suspended - Clinical trials for Acute Ischemic Stroke

Study of Compound Edaravone Injection for Treatment of Acute Ischemic Stroke

Start date: November 15, 2021
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to confirm the efficacy of compound Edaravone Injection via intravenous infusion every 12 hours in the patients with Acute Ischemic Stroke(AIS) in a double-blind, active-controlled manner. The study is also to examine the safety of compound Edaravone Injection for the AIS patients.

NCT ID: NCT04891913 Suspended - Clinical trials for Acute Ischemic Stroke

SY007 in Patients With Acute Ischemic Stroke

Start date: July 1, 2023
Phase: Phase 1
Study type: Interventional

This Phase 1b multiple center, randomized, double-blind, placebo-controlled study is a dose escalation trial evaluating the safety, tolerability, PK characteristics and efficacy of SY-007 after injection in acute ischemicstroke patients. The immunogenicity of SY-007 will be evaluated and this study will provide the recommended dosage for subsequent clinical trials.

NCT ID: NCT04064658 Suspended - Moyamoya Disease Clinical Trials

Effects of Remote Ischemic Pre-Conditioning in Moyamoya Disease Patients

RIME
Start date: October 1, 2019
Phase: N/A
Study type: Interventional

In the present study, investigators evaluated whether RIPC reduce the major neurological complications in adult moyamoya disease patients undergoing encephaloduroarteriosynangiosis (EDAS).

NCT ID: NCT04023058 Suspended - Clinical trials for Ischemic Mitral Regurgitation

Stress Echo for Ischemic Mitral Valve Surgery

SURVIVE
Start date: January 1, 2020
Phase: N/A
Study type: Interventional

Comparison patients with CABG alone vs. CABG+mitral surgery with non-massive ischaemic mitral regurgitation (IMR) depending on stress echo data.

NCT ID: NCT03253328 Suspended - Diabetes Mellitus Clinical Trials

N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes

Start date: December 15, 2016
Phase: N/A
Study type: Interventional

In this pilot clinical study the investigators propose to conduct a prospective, randomized, double-blinded, placebo-controlled clinical trial for 30 days for participants with critical limb ischemia (CLI) who undergo a major (above-knee or below-knee) lower extremity amputation. By exploring the primary endpoints we aim to determine whether NAC can affect amputation stump perfusion and healing. Based on preclinical data, the investigators hypothesize that NAC will augment both amputation stump perfusion as well as healing. The investigators will utilize the data from this trial to determine the true effect size that is necessary for a larger clinical trial to determine the clinical efficacy of NAC is healing surgical sites such as major lower extremity amputation stumps.

NCT ID: NCT03175744 Suspended - Clinical trials for Critical Limb Ischemia

Stellarex DCB Versus Standard Balloon Angioplasty for Treatment of Below-The-Knee (BTK) Arteries

ILLUMENATE-BTK
Start date: May 24, 2017
Phase: N/A
Study type: Interventional

The purpose is to demonstrate the safety and effectiveness of the Stellarex DCB for the treatment of stenosis or occlusions of below-the-knee arteries.

NCT ID: NCT03098732 Suspended - Stroke, Acute Clinical Trials

Magnetically Enhanced Diffusion for Acute Ischaemic Stroke (MEDIS) Trial

MEDIS
Start date: March 22, 2017
Phase: N/A
Study type: Interventional

The objective of the MEDIS study is to determine if subjects experiencing an Acute Ischaemic Stroke due to large vessel occlusion, treated with IV tPA combined with the MED procedure have a greater likelihood of recanalisation 30-90 minutes after the completion of tPA infusion than subjects treated with IV tPA (plus sham device). Safety of the MED System Procedure will be evaluated by the incidence of symptomatic PH-2 haemorrhagic transformation within 24 hours following the procedure. Lastly, a health economics study will be conducted to estimate health care costs for each treatment.

NCT ID: NCT02785120 Suspended - Ischemic Stroke Clinical Trials

A Study to Evaluate the Efficacy and Safety of TF0023 Spray on Subjects With Ischemic Strokes

TF0023
Start date: March 1, 2017
Phase: Phase 2
Study type: Interventional

This is a phase 2, multicenter, randomized, double-blind (within dose), placebo controlled, parallel-group, dose-range finding study to evaluate the efficacy and safety of TF0023 spray versus placebo in functional improvement of patients with ischemic strokes under standard of care.

NCT ID: NCT02533778 Suspended - Ischemic Stroke Clinical Trials

ARISE: After 8 Hours Reperfusion in Ischemic Stroke Embolization

ARISE
Start date: July 2015
Phase: N/A
Study type: Interventional

A prospective pilot study to evaluate the recanalization and safety of mechanical thrombectomy through a cerebral angiogram in patients with stroke symptoms last seen normal between 8 - 24 hours.