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Inflammation clinical trials

View clinical trials related to Inflammation.

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NCT ID: NCT02379676 Recruiting - Clinical trials for Endothelial Dysfunction

Effect of Ticagrelor Versus Clopidogrel on Endothelial Dysfunction and Vascular Inflammation

Start date: January 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the effects of ticagrelor and clopidogrel on endothelial dysfunction and vascular inflammation Ticagrelor will lead to beneficial pleiotropic effects compared with treatment with clopidogrel in patients receiving a drug-eluting stents (DES) during percutaneous coronary intervention (PCI) for non-ST-segment acute coronary syndrome (NSTE-ACS) beyond 1 month after the index event. Ticagrelor treatment will improve percent flow-mediated dilation (FMD) values and reduces inflammatory gene expression on peripheral blood mononuclear cells.

NCT ID: NCT02378259 Active, not recruiting - Obesity Clinical Trials

Randomized Clinical Trial; Medical vs Bariatric Surgery for Adolescents (13-16 y) With Severe Obesity

AMOS2
Start date: August 15, 2014
Phase: N/A
Study type: Interventional

Severe childhood obesity is associated with both immediate and chronic health problems and a severe impact on psychosocial development. Medical and behavioural interventions rarely result in the significant, durable weight loss necessary to improve health outcomes. This is a randomised clinical trial where 50 adolescents, 13-16 years of age, will be randomised to either early bariatric surgery (Roux-en-Y gastric bypass) or intense conservative treatment and possibly surgery after two years of non-surgical treatment or as they have become 18 years.

NCT ID: NCT02378077 Completed - Obesity Clinical Trials

Understanding the Relationship Between Inflammation and Insulin Resistance in the Adipose Tissue

Start date: August 2014
Phase: N/A
Study type: Interventional

This study is being done to better understand the relationship between inflammation and insulin resistance in your Adipose (fat) Tissue .

NCT ID: NCT02378064 Completed - Coronary Disease Clinical Trials

Comparison of Fimasartan Versus Amlodipine Therapy on Carotid PlaquE Inflammation

FACE
Start date: May 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effects of angiotensin receptor 1 blocker versus calcium channel blocker on atherosclerotic plaque inflammation using serial FDG PET/CT imaging of carotid artery.

NCT ID: NCT02376738 Completed - Clinical trials for Coronary Artery Disease

Regional Activation of Leukocytes in Coronary Artery Disease

REAL-CAD
Start date: July 2007
Phase: N/A
Study type: Observational

This study aims to evaluate the role of leukocyte activation in coronary artery disease

NCT ID: NCT02375373 Completed - Inflammation Clinical Trials

Effects of Adding Chickpeas to the American Diet (Long Term Study)

Start date: April 2015
Phase: N/A
Study type: Observational

This prospective study will assess the effects of adding legumes, especially chick peas, to the diet of healthy adults on the commensal bacteria from feces of human subjects and resulting self-reported GI symptoms as well as markers of immune function.

NCT ID: NCT02375347 Completed - Inflammation Clinical Trials

Effects of Adding Chickpeas to the American Diet on Fecal Microbiota Composition and Markers of Inflammation

Start date: March 2015
Phase: N/A
Study type: Observational

This prospective study will assess the effects of adding legumes, especially chick peas, to the diet of healthy adults on the commensal bacteria from feces of human subjects and resulting self-reported GI symptoms as well as markers of immune function.

NCT ID: NCT02372630 Completed - Type 2 Diabetes Clinical Trials

The Effect of LINAGLIPTIN on Inflammation, Oxidative Stress and Insulin Resistance in Obese Type 2 Diabetes Subjects

1971
Start date: May 23, 2014
Phase: Phase 4
Study type: Interventional

This is a single center, prospective randomized double blind, parallel and placebo controlled study to evaluate oxidative stress and inflammation before and after treatment with linagliptin for 12 weeks. We will also, testing whether Linagliptin is an insulin sensitizer.

NCT ID: NCT02370966 Completed - Inflammation Clinical Trials

Berry Intake - Effects on Systemic and Oral Inflammation

Start date: February 2015
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine whether intake of berry powder effective in the treatment of systemic and oral inflammation.

NCT ID: NCT02369666 Completed - Inflammation Clinical Trials

LycoRed 40051 Product as a Countermeasure to Exercise Stress

Start date: November 2014
Phase: N/A
Study type: Interventional

The primary purpose of this study is to determine if 4-weeks ingestion of LycoRed (code 40051) product containing a mixture of tomato extract with carotenoids and phytochemicals by endurance runners attenuates inflammation, muscle damage and soreness, and oxidative stress during 24 hours recovery from a 2-h running bout.