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Infection clinical trials

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NCT ID: NCT01746108 Completed - Clinical trials for Infections, Streptococcal

Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Pneumococcal Vaccine (Synflorix™) When Administered to Children Who Are at an Increased Risk of Pneumococcal Infection

Start date: June 18, 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the immunogenicity, safety and reactogenicity of GSK Biologicals' 10Pn-PD-DiT vaccine in children aged between 2 and 17 years of age having asplenia, splenic dysfunction or complement deficiencies. In addition, this study will include an age-matched control group of healthy children aged 24-59 months in order to descriptively compare the immunogenicity of 10Pn-PD-DiT vaccine in the at-risk population to that of the general, healthy population one month after each pneumococcal vaccination.

NCT ID: NCT01746095 Completed - Cystic Fibrosis Clinical Trials

Efficacy and Safety Study of AeroVanc for the Treatment of Persistent MRSA Lung Infection in Cystic Fibrosis Patients

Start date: March 2013
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether AeroVanc treatment is safe and effective in reducing the number of MRSA colony forming units in the lungs of cystic fibrosis patients.

NCT ID: NCT01745679 Completed - Meningitis Clinical Trials

Pharmacological Study of High Doses of Ceftriaxone in Meningitidis

Start date: December 2012
Phase: Phase 4
Study type: Interventional

The aim of the study is to describe the concentrations of Ceftriaxone at the steady state, in patients treated for meningitis, to determine pharmacokinetic parameters at high dose in this population. Additionally, we aimed to detect adverse effect, especially neurological trouble related to Ceftriaxone toxicity.

NCT ID: NCT01745328 Recruiting - Clinical trials for Recurrent Urinary Tract Infection

Treatment of Recurrent Urinary Tract Infection (RUTI) by Traditional Chinese Medicine

Start date: January 2009
Phase: N/A
Study type: Interventional

Traditional Chinese Medicine (TCM) could be used to treat Recurrent urinary tract infection (RUTI).

NCT ID: NCT01741649 Completed - Clinical trials for Surgical Wound Infection

Clorhexidine Versus Povidone for the Prevention of Surgical Site Infection After Cesarean Section

Start date: October 2012
Phase: N/A
Study type: Interventional

Many solutions are used for cleaning the skin of a patient previous to a surgery. Although the efficacy of clorhexidine has been proved in other surgical procedures, there is only a retrospective study in cesarean section (they report no benefit of one solution over the other). The investigators would like to evaluate the difference in surgical site infection in patients after cesarean section comparing preparation of the skin with clorhexidine versus povidone.

NCT ID: NCT01739673 Completed - Clinical trials for Infectious Keratitis

Ultraviolet-A and Riboflavin Treatment for Infectious Keratitis

Start date: August 2011
Phase: N/A
Study type: Interventional

This study is to evaluate the efficacy of ultraviolet-A (UVA) and riboflavin application (also often referred to as corneal collagen crosslinking) as a method to enhance treatment of infectious keratitis.

NCT ID: NCT01737307 Completed - Infection Clinical Trials

Effect of Fluoride Varnish and CPP-ACP on Oral and Salivary Symptoms During Chemotherapy

Start date: March 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study was to investigate the effect of Fluoride varnish and Casein Phospho-Peptide Amorphous Calcium Phosphate (CPP-ACP) containing paste on oral symptoms and salivary characteristics in patients under chemotherapy.

NCT ID: NCT01736644 Completed - Surgery Clinical Trials

Bipolar Sealer Aquamantys Use in Total Knee Replacement

Start date: October 2012
Phase: N/A
Study type: Interventional

This study will compare the clinical outcomes for patients undergoing a total knee replacement using a bipolar sealer, the Aquamantys® System, as compared to standard electrocautery. Total blood loss during the hospital stay and knee mobility and discharge factors will be analyzed.

NCT ID: NCT01735136 Completed - Clinical trials for Helicobacter Pylori Infection

Efficacy and Safety of InSan Bamboo Salt on Improvement of Helicobacter Pylori Infection

Start date: November 21, 2012
Phase: N/A
Study type: Interventional

The investigators performed a 4-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of InSan Bamboo Salt on improvement of Helicobacter pylori infection. The investigators measured improvement of Helicobacter pylori infection parameters , including 14C-UBT(Urea breath test), and subjects' symptoms, and monitored their blood pressure.

NCT ID: NCT01735084 Completed - Cough Clinical Trials

Using Pneumococcal Vaccines in Combination for Maximum Protection From Ear and Lung Infections in First 3 Years of Life

PREV-IX_B
Start date: March 12, 2013
Phase: Phase 4
Study type: Interventional

HYPOTHESES: 1. That infants receiving PHiD-CV10 as a booster at 12 months of age, compared to controls having no PHiD-CV10 booster (i.e. standard PCV13), will have higher HiD antibody levels, lower carriage of NTHi, and less tympanic membrane perforation at 18 and 36 months of age. 2. That infants receiving PCV13 as a booster at 12 months of age, compared to controls having no PCV13 (i.e. PHiD-CV10 booster) will have higher antibody levels to serotypes 3, 6A and 19A, less carriage of these serotypes, and less tympanic membrane perforation at 18 and 36 months of age.