Hypertension Clinical Trial
Official title:
Trace Elements and CVD Risk Factors Among Young Adults
Cardiovascular disease (CVD) affects millions of people in the United States; each year, more people die from CVD than from any other disease. There are many dietary and lifestyle factors that may increase the risk of developing CVD. Preliminary research has shown that the presence of certain trace elements may be associated with the development of CVD. This study will examine toenail clippings and laboratory data to evaluate the link between trace elements and CVD risk factors in young adults.
CVD is a disorder that affects the heart's ability to function normally. The most common
cause of heart disease is narrowing or blockage of the coronary arteries, which supply blood
to the heart. There are many risk factors for CVD, including inflammation, high blood
pressure, high cholesterol, and obesity. Small quantities of trace elements, also known as
micronutrients, are essential in maintaining a healthy body. Research has shown that some
trace elements may be associated with the development of CVD, but more research is needed to
confirm this connection. This study will examine concentrations of several trace elements in
toenail samples of young adults participating in the Coronary Artery Risk Development in
Young Adults (CARDIA) study. The CARDIA study is measuring changes in CVD risk factors in
individuals as they age and is identifying lifestyle habits that influence those changes.
The purpose of this study is to determine the link between trace elements and CVD risk
factors in young adults. The results of this study may help to identify whether dietary,
lifestyle, or environmental factors can be modified at a young age to prevent the
development of CVD.
This study will examine laboratory and medical history data of participants who are already
enrolled in the CARDIA study; there are no additional study visits specifically for this
study. Toenail samples collected from participants during their Year 2 CARDIA study visit in
the late 1980's will be examined to determine the presence of selenium, chromium, arsenic,
and mercury. Participants' CARDIA study data will be reviewed and several CVD risk factors
will be analyzed, including the thickness of heart arteries; calcium buildup within the
arteries; inflammatory markers, such as high sensitivity C-reactive protein and interleukin
6; blood pressure levels; body weight; and levels of cholesterol, fat, and sugar.
;
Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT04591808 -
Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and Dyslipidemia
|
Phase 3 | |
| Recruiting |
NCT04515303 -
Digital Intervention Participation in DASH
|
||
| Completed |
NCT05433233 -
Effects of Lifestyle Walking on Blood Pressure in Older Adults With Hypertension
|
N/A | |
| Completed |
NCT05491642 -
A Study in Male and Female Participants (After Menopause) With Mild to Moderate High Blood Pressure to Learn How Safe the Study Treatment BAY3283142 is, How it Affects the Body and How it Moves Into, Through and Out of the Body After Taking Single and Multiple Doses
|
Phase 1 | |
| Completed |
NCT03093532 -
A Hypertension Emergency Department Intervention Aimed at Decreasing Disparities
|
N/A | |
| Completed |
NCT04507867 -
Effect of a NSS to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III
|
N/A | |
| Completed |
NCT05529147 -
The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail Elderly
|
||
| Recruiting |
NCT05976230 -
Special Drug Use Surveillance of Entresto Tablets (Hypertension)
|
||
| Recruiting |
NCT06363097 -
Urinary Uromodulin, Dietary Sodium Intake and Ambulatory Blood Pressure in Patients With Chronic Kidney Disease
|
||
| Completed |
NCT06008015 -
A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1015" and Co-administration of "BR1015-1" and "BR1015-2" Under Fed Conditions in Healthy Volunteers
|
Phase 1 | |
| Completed |
NCT05387174 -
Nursing Intervention in Two Risk Factors of the Metabolic Syndrome and Quality of Life in the Climacteric Period
|
N/A | |
| Completed |
NCT04082585 -
Total Health Improvement Program Research Project
|
||
| Recruiting |
NCT05121337 -
Groceries for Black Residents of Boston to Stop Hypertension Among Adults Without Treated Hypertension
|
N/A | |
| Withdrawn |
NCT04922424 -
Mechanisms and Interventions to Address Cardiovascular Risk of Gender-affirming Hormone Therapy in Trans Men
|
Phase 1 | |
| Active, not recruiting |
NCT05062161 -
Sleep Duration and Blood Pressure During Sleep
|
N/A | |
| Completed |
NCT05087290 -
LOnger-term Effects of COVID-19 INfection on Blood Vessels And Blood pRessure (LOCHINVAR)
|
||
| Not yet recruiting |
NCT05038774 -
Educational Intervention for Hypertension Management
|
N/A | |
| Completed |
NCT05621694 -
Exploring Oxytocin Response to Meditative Movement
|
N/A | |
| Completed |
NCT05688917 -
Green Coffee Effect on Metabolic Syndrome
|
N/A | |
| Recruiting |
NCT05575453 -
OPTIMA-BP: Empowering PaTients in MAnaging Blood Pressure
|
N/A |