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Hypercholesterolemia clinical trials

View clinical trials related to Hypercholesterolemia.

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NCT ID: NCT00133094 Completed - Clinical trials for Hypercholesterolemia

Systematic Management of High Cholesterol Utilizing Computer Monitoring

Start date: June 2006
Phase: N/A
Study type: Interventional

Employing a physician-directed case management system, utilizing a Certified Registered Nurse Practitioner (CRNP) in conjunction with computer-based decision support technology (CDST) will result in significantly lower total cholesterol and a lower low density lipoprotein cholesterol in a group of subjects enrolled in a general medical clinic compared to subjects managed by primary care providers in the usual care group.

NCT ID: NCT00132717 Completed - Clinical trials for Hypercholesterolemia

A 12 Week Study of MK0653A in Patients Who Have Been Hospitalized for a Possible Heart Problem (0653A-808)

Start date: January 1, 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the effect of an investigational cholesterol-lowering drug in patients who are currently taking an approved medication for hypercholesterolemia (high cholesterol levels) and have been hospitalized for a heart problem.

NCT ID: NCT00129402 Completed - Clinical trials for Hypercholesterolemia

Effects of Ezetimibe With Simvastatin in the Therapy of Adolescents With HeFH (Study P02579)

Start date: August 2005
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, controlled, parallel-group, multicenter, Phase-3 study to evaluate the efficacy and safety of ezetimibe with simvastatin taken alone in subjects ages 10-17 years with Heterozygous Familial Hypercholesterolemia.

NCT ID: NCT00120718 Completed - Atherosclerosis Clinical Trials

The Effect of Fasudil on Vascular Function in Humans

Start date: June 2002
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate how the rho kinase inhibitor, fasudil, affects vascular function in patients with atherosclerosis and hyperlipidemia.

NCT ID: NCT00115232 Completed - Inflammation Clinical Trials

Inflammatory Profiles of Children at High Risk for Atherosclerosis

Start date: July 2004
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate levels of inflammatory mediators in children at risk for cardiovascular disease due to family history. We are measuring inflammatory markers in two groups of children and their parents: children with a family history of early atherosclerotic heart disease (cases), and healthy children without such a family history (controls). The design is a cross-sectional study, gathering a fasting blood sample and clinical and behavioral data on children and a parent.

NCT ID: NCT00114855 Completed - Hyperlipidemia Clinical Trials

The Effect of Hypocol® on Lipids in Subjects With Mild Hypercholesterolemia and Mildly Elevated Blood Glucose

Start date: March 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to determine to what degree Hypocol® (Red Yeast Rice) may lower low density lipoprotein (LDL)-cholesterol in a European population. The effect of Red Yeast Rice on fasting blood glucose and inflammatory markers will also be investigated.

NCT ID: NCT00114491 Completed - Atherosclerosis Clinical Trials

Rosuvastatin Affecting Aortic Valve Endothelium

Start date: September 2003
Phase: Phase 4
Study type: Observational

Recent studies support the hypothesis that aortic stenosis (AS) develops due to atherosclerosis affecting the aortic valve endothelium. The study’s aim was to assess Rosuvastatin on the hemodynamic progression and inflammatory markers of AS by treating low-density lipoprotein (LDL) in patients with AS according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATPIII) guidelines for one year.

NCT ID: NCT00110435 Completed - Clinical trials for Type 2 Diabetes Mellitus

A Multicenter Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Products in Patients With Type 2 Diabetes Mellitus and Hypercholesterolemia (MK-0653A-077)

Start date: May 2005
Phase: Phase 3
Study type: Interventional

The purpose of this 10-week study is to compare the reduction in cholesterol following treatment with two different marketed drugs, in patients with type 2 diabetes mellitus and hypercholesterolemia.

NCT ID: NCT00109603 Completed - HIV Infections Clinical Trials

Effect of Tenofovir Disoproxil Fumarate on Lipid Levels in HIV Infected Adults on Stable Anti-HIV Drug Therapy

Start date: May 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effect of the anti-HIV drug tenofovir disoproxil fumarate (TDF) on lipid levels in HIV infected adults on stable anti-HIV drug therapy. Study hypothesis: The addition of TDF to stable background antiretroviral therapy in HIV infected individuals with dyslipidemia will result in a reduction of non-HDL after 12 weeks of treatment.

NCT ID: NCT00107744 Completed - Hypertension Clinical Trials

Clinical Trial of Protein and Blood Pressure

ProBP
Start date: September 2003
Phase: N/A
Study type: Interventional

The purpose of this randomized, double-blind, controlled trial is to examine the effect of soybean protein supplementation on blood pressure in persons with prehypertension or stage-1 hypertension.