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Diabetes Mellitus, Type 2 clinical trials

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NCT ID: NCT01440517 Terminated - Heart Failure Clinical Trials

Results of Tc99m-Maraciclatide Scintigraphy in Subjects With Diabetes Mellitus and Heart Failure With Preserved Left Ventricular Ejection Fraction

Start date: August 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the results of 99mTc maraciclatide scintigraphy in diabetic subjects with HFPEF. A maximum of 20 subjects with Diabetes Mellitus (DM) and Heart Failure With Preserved Left Ventricular Ejection Fraction (HFPEF) will be enrolled and imaged with 99mTc maraciclatide. In addition, a maximum of 10 subjects with DM and diastolic dysfunction but no diagnosis of heart failure (HF) will be enrolled and imaged with 99mTc-maraciclatide.

NCT ID: NCT01393873 Terminated - Obesity Clinical Trials

Progression of Diabetic Retinopathy Post Bariatric Surgery (BS)

Start date: July 2011
Phase: N/A
Study type: Observational

Studies conducted assessing diabetic eye disease have shown a progression of diabetic retinopathy with rapid improvement of glycemic control during pregnancy and in patients with type 1 diabetes. It is also well documented that bariatric surgery may result in rapid improvement of glycemic control in obese patients with type 2 diabetes. To our knowledge the progression of diabetic eye disease seen in pregnancy and type 1 diabetes has not been studied in obese type 2 diabetics undergoing bariatric surgery. To this end, this study will examine the effects of rapid glycemic control which is seen in type 2 diabetics following bariatric surgery on the progression of diabetic retinopathy.

NCT ID: NCT01387659 Terminated - Diabetes Clinical Trials

Evaluate Tolerability of Myfortic®/Simulect® and Tacrolimus Without Steroids in Three Patient Populations

Start date: March 2011
Phase: N/A
Study type: Interventional

This study is designed to evaluate the tolerability of Myfortic®/Simulect® combination in diabetic patients in a steroid free regimen. Due to the diverse ethnicity of our transplant recipient population, the study will determine any different responses, including autoimmunity, between Hispanic, and Caucasian, patients.

NCT ID: NCT01372163 Terminated - Clinical trials for Diabetes Mellitus, Type 2

A Study Of PF-05190457 In Healthy Volunteers And Type-2 Diabetic Patients

Start date: July 2011
Phase: Phase 1
Study type: Interventional

The purpose of the study is to evaluate the safety and tolerability of PF-05190457 after administration of multiple doses to healthy volunteers and Type 2 diabetic patients and to evaluate the plasma drug concentrations after multiple doses.

NCT ID: NCT01368536 Terminated - Hypertension Clinical Trials

Study to Evaluate the Efficacy and Safety of the Combination of Valturna and Amlodipine or Valturna and Chlorthalidone Versus Valturna Alone in Patients With Stage 2 Hypertension and Diabetes

VALENCIA
Start date: May 2011
Phase: Phase 4
Study type: Interventional

This was a study to assess the safety and efficacy of Valturna and amlodipine or Valturna and chlorthalidone when compared to Valturna alone in patients with stage 2 hypertension and diabetes mellitus 2.

NCT ID: NCT01357148 Terminated - Clinical trials for Diabetes Mellitus, Type 2

A Post Marketing Safety Study of Sitagliptin Phosphate/Metformin Hydrochloride (JANUMET®) (MK-0431A-235)

Start date: March 2009
Phase: N/A
Study type: Observational

The primary objective of this study is to obtain safety information on the use of sitagliptin phosphate/metformin hydrochloride (HCl) (JANUMET®) from endocrinologists, diabetologists, internists, and general practitioners.

NCT ID: NCT01351675 Terminated - Clinical trials for Diabetes Mellitus, Type 2

Bardoxolone Methyl Evaluation in Patients With Chronic Kidney Disease and Type 2 Diabetes

BEACON
Start date: June 30, 2011
Phase: Phase 3
Study type: Interventional

This study assesses the efficacy of bardoxolone methyl relative to placebo in delaying progression to end-stage renal disease (ESRD) and cardiovascular deaths in patients with Stage 4 Chronic Kidney Disease (CKD) and type 2 diabetes receiving standard of care.

NCT ID: NCT01350102 Terminated - Clinical trials for Foot Ulcer, Diabetic

The Relationship of Hemoglobin A1c and Diabetic Wound Healing

Start date: February 2012
Phase: Phase 4
Study type: Interventional

The purpose of this study is to investigate the relationship of hemoglobin A1c in diabetic wound healing. Additionally, a comparison of two wound dressings, AmeriGel® (Amerx Health Care Corp., Clearwater, FL) and Bacitracin, with and without vitamin C supplementation, will be done to evaluate impact on time to wound closure.

NCT ID: NCT01349114 Terminated - Hypertension Clinical Trials

Effect of the Direct Renin Inhibitor Aliskiren on Endothelial Function and Arterial Stiffness in Diabetic Subjects

Start date: June 2011
Phase: Phase 4
Study type: Interventional

The study will evaluate the effects of the direct renin inhibitor, aliskiren, on flow-mediated dilation of the brachial artery and on central aortic pressure in diabetic patients with pre-hypertension or Stage 1 hypertension.

NCT ID: NCT01336673 Terminated - Clinical trials for Diabetes Mellitus Type 2

Glucophage XR® Observational Study

Start date: June 2011
Phase: N/A
Study type: Observational

This is a non-interventional, prospective study where no visits or additional interventions to the daily practice of the physician will be performed. Glucophage XR® has recently been available in Thailand for the treatment of patients with type 2 diabetes. A prospective observational study will be valuable to provide information on the day-to-day experience of using Glucophage XR® in the management of this patient population. The data may provide an insight into the use of Glucophage XR® in routine clinical practice in Thailand.