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Diabetes Mellitus, Type 2 clinical trials

View clinical trials related to Diabetes Mellitus, Type 2.

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NCT ID: NCT03607448 Completed - Diabetes Mellitus Clinical Trials

Freestyle Libre Flash Glucose Monitoring System

Start date: July 23, 2018
Phase:
Study type: Observational

The purpose of this study is to characterize the Freestyle Libre Flash Glucose Monitoring System performance with respect to YSI reference venous plasma sample measurements.

NCT ID: NCT03607201 Completed - Heart Failure Clinical Trials

Acute Coronary Syndrome in Diabetic Patients

Start date: August 1, 2017
Phase:
Study type: Observational

This study aims to compare the clinical profile and outcomes of acute coronary syndrome patients with diabetes and without diabetes.

NCT ID: NCT03604224 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study to Observe Clinical Effectiveness of Canagliflozin 300 mg Containing Treatment Regimens in Indian Type 2 Diabetes Participants With BMI>25 kg/m^2, in Real World Clinical Setting

Start date: September 5, 2018
Phase:
Study type: Observational

The purpose of this study is to observe clinical effectiveness of canagliflozin by mean haemoglobin A1c (HbA1C) and body weight changes from baseline to 12 weeks in Indian type 2 diabetes participants.

NCT ID: NCT03603704 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study of LY3209590 in Japanese Participants With Type 2 Diabetes

Start date: August 17, 2018
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate the safety of a study drug known as LY3209590 in Japanese participants with type 2 diabetes. Side effects and tolerability will be documented. Blood samples will be taken to compare how the body handles the drug and how it affects blood sugar levels. The study will last about four weeks, not including screening. Screening is required within 4 weeks before the start of the study.

NCT ID: NCT03602846 Completed - Clinical trials for Diabetes, Gestational

Diabetes in Pregnancy and Pregnancy Outcomes

Start date: January 2015
Phase:
Study type: Observational

To compare the clinical, glycemic profile and therapy as well as pregnancy complications and infant mortality among diabetic mothers in Indonesia.

NCT ID: NCT03601884 Completed - Diabetes Mellitus Clinical Trials

Effectiveness of OHP in Improving Self-efficacy in Patients With Diabetes Mellitus

OHP
Start date: October 5, 2018
Phase: N/A
Study type: Interventional

Addressing the increasing trend in diabetes and mental illness co-morbidities, Malaysia is currently in need of a self- management program that promotes patient empowerment and overall well-being - beyond education. Committing to the self-care behaviours is highly dependent on the individual's self-efficacy. Self-efficacy has been shown to have a direct positive relationship with self-care behaviours, direct negative relationship with psychological distress and depression. Self-efficacy has also been found to hold a mediating effect on the relationship between emotional distress and self-care behaviours. The objective of this study is to assess the effectiveness of a self-management program for patients with diabetes, the Optimal Health Program (OHP) in improving self-efficacy, depression, anxiety, diabetes distress, well-being and self-care. This study is a randomized controlled trial study of patients with diabetes attending the four diabetes health clinics within the Putrajaya District. Eligible patients will be randomly allocated to either treatment as usual (TAU) or OHP and treatment as usual (OHP + TAU). The treatment as usual group (TAU) participants will be invited to participate in the OHP at the end of the study. The participants in the OHP + TAU will attend 5 weekly 1.5 hour sessions and a booster session at 3 months. Following ethics approval, recruitment and training will commence in September, data collection expected to be until April 2020. It is hypothesized that the OHP + TAU group will have higher self-efficacy, well-being and self-care scores and reduced depression, anxiety, diabetes related-distress and HbA1c. This study will contribute towards the gap in the literature in the effectiveness of a self-efficacy enhancing psychosocial self-management program among diabetes patients in Malaysia within a primary care setting.

NCT ID: NCT03598738 Completed - Clinical trials for Diabetes Mellitus, Type 2

The Effect of Esomeprazole on Type 2 Diabetes

Start date: December 1, 2015
Phase: N/A
Study type: Interventional

The investigators aimed to prospectively investigate the effects of esomeprazole on glycaemic control in patients with type 2 diabetes mellitus. The investigators also aimed to associate this effect with gastrin levels. Thirty-two type 2 diabetes mellitus objects were recruited into intervention (n=16) and control (n=16) groups. The participants in the intervention group were prescribed 40 mg of esomeprazole treatment for three months. At the beginning of the study and at month 3, HbA1c level (%) and gastrin levels (pmol/L) of participants were assessed. Then the baseline and 3rd month data of groups were compared.

NCT ID: NCT03598621 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Research Study to Look at Similarity Between Semaglutide Versions in Different Injection Tools

Start date: July 23, 2018
Phase: Phase 1
Study type: Interventional

This study will compare four different semaglutide versions and different injection tools. The study aims to show similar levels of semaglutide in the blood using different versions of semaglutide. The researchers also want to look at how well the injection tools work. Participants will get two versions of semaglutide at two separate dosing visits. One of them is a version that doctors already can prescribe and the other will be one of the new versions. Which version participants get first is decided by chance. Participants will get semaglutide as an injection under the skin. The time between injections is 7 to 8 weeks. The study will last for about 16 weeks. Participants will have 27 study visits with the study doctor. For two of the visits, participants will stay at the clinic for 4 days and 3 nights.

NCT ID: NCT03596450 Completed - Clinical trials for Diabetes Mellitus, Type 2

Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial

Start date: July 13, 2018
Phase: Phase 4
Study type: Interventional

The main purpose of this study is to compare the effects of semaglutide (Ozempic®) with the effects of other treatments for type 2 diabetes in a normal practice setting. The participant will be assigned by chance (like flipping a coin) to one of the following treatment groups: Group 1: semaglutide (Ozempic®) (by injection into skin) Group 2: standard of care antidiabetic medication (oral or injectable). The participant has an equal chance of being in either of the treatment groups. Neither the participant nor the study doctor or study staff will be able to pick which group the participant is in, but the participant will know which study drug the participant has been assigned to. The study doctor will provide the participant with a prescription for the study diabetes medication based on the treatment group the participant is assigned. The participation will last about 2 years.

NCT ID: NCT03596177 Completed - Obesity Clinical Trials

A Study to Evaluate the Effect of MEDI0382 on Energy Balance in Overweight and Obese Participants With Type 2 Diabetes Mellitus

Start date: September 26, 2018
Phase: Phase 2
Study type: Interventional

An exploratory study to evaluate the effect of MEDI0382 on energy balance in overweight and obese participants with type 2 diabetes mellitus