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Diabetes Mellitus, Type 2 clinical trials

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NCT ID: NCT05898750 Completed - Diabetes Clinical Trials

Antidiabetic Potiential of Moringa and Dom Extract

Start date: April 22, 2023
Phase: Early Phase 1
Study type: Interventional

The Antidiabetic potential of Hyphaene thebaica fruits and Moringa oleifera leaves will be investigated in diabetic patients (type 2). The patients will be maintained on tea of both drugs for 6 weeks. The fasting blood glucose levels of patients will be checked on a daily basis. Other blood biomarkers will be also reported such as insulin concentration, Lipid profile, liver enzymes, c-peptide and glycated hemoglobin

NCT ID: NCT05897528 Completed - COVID-19 Clinical Trials

Insulin Regulation and Severity of Severe Acute Respiratory Syndrome COVID-19 Infection

Start date: October 14, 2021
Phase:
Study type: Observational

The Coronavirus Disease of 2019 (COVID-19) pandemic has caused an international healthcare crisis and produced a large healthcare burden. Diabetes mellitus is a common disease that can be controlled via pharmacologic agents; however, many patients have poor glycemic control, leading to disease-related complications. Diabetes mellitus has been reported in the literature to be associated with increasing morbidity and mortality in COVID-19 patients, and some hypothesize that this is due to insulin dysregulation propagating a pro-inflammatory state. The investigators aim to contribute to the growing body of literature that assesses the associations between glucose homeostasis and COVID-19 disease severity and mortality.

NCT ID: NCT05896319 Completed - Clinical trials for Diabetes Mellitus, Type 2

Hyaluronic Acid Treatment of the Post-extraction Tooth Socket Healing in Subjects With Diabetes Mellitus Type 2

Start date: September 7, 2022
Phase: N/A
Study type: Interventional

The aim of the present split-mouth study was to investigate the effect of Hyaluronic Acid (HA) in improving the post-extraction tooth socket healing in subjects with diabetes mellitus type 2. The null hypothesis was that HA can significantly improve the post extractive healing of diabetic patients compared with no treatment. 36 patients with diabetes mellitus type 2 requiring bilateral extraction of the homologous, not included, teeth were enrolled. After the extractions carried out in the same appointment, following the split-mouth design of the study, one site was randomly assigned to the test (T) group, while the other one was assigned to the control group (C). T group included: Post-operative application of Hyaluronic acid gels 3 times per day C group included: no treatment. Patients were then followed after 3, 7,14 and 21 days and the healing of each socket was evaluated and compared between the 2 groups.

NCT ID: NCT05893784 Completed - Diabetes Mellitus Clinical Trials

The Effect of Progressive Relaxation Exercises Applied to Individuals With Diabetes on Fatigue and Sleep

Start date: January 20, 2022
Phase: N/A
Study type: Interventional

The aim of this study was to examine the effect of the progressive relaxation exercises applied to the individuals with diabetes on fatigue and sleep. This randomized controlled study was a single-blind, parallel intervention and control group experimental study. The researcher applied the training for the progressive relaxation exercises to the intervention group. Socio-demographic data, 'Pittsburgh Sleep Quality Index' and 'The Fatigue Severity Scale' were used for the study.

NCT ID: NCT05887999 Completed - Clinical trials for Diabetes Mellitus, Type 1

A Study of LY3532226 in Participants With Type 1 Diabetes Mellitus

Start date: June 12, 2023
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate the response of glucagon to insulin-induced low blood sugar after administration of the study drug LY3532226 in participants with type 1 diabetes mellitus (T1DM). The study will also evaluate if LY3532226 helped participants to recover from insulin-induced low blood sugar condition compared to placebo. The study will last approximately 16 weeks excluding screening period.

NCT ID: NCT05887895 Completed - Diabetes Clinical Trials

To Compare the Pharmacokinetics and Pharmacodynamics of HR20014, INS068 and INS062 After Single Subcutaneous Injection in Healthy Subjects

Start date: May 23, 2023
Phase: Phase 1
Study type: Interventional

This is a single-center, randomized, open, six-sequence, three-period crossover phase I clinical trial in healthy subjects to compare the PK/PD and safety profiles of single dose of HR20014, INS068, and INS062. In this study, 12 subjects were randomly assigned to 6 administration sequences in a ratio of 1:1:1:1:1:1, and HR20014, INS068 or INS062 injection were given subcutaneously three times before and after each sequence.

NCT ID: NCT05887544 Completed - Clinical trials for Diabetes Mellitus, Type 2

Towards Objective Dietary Assessment in Large-scale Studies

ODA
Start date: June 1, 2023
Phase:
Study type: Observational

Enabling an objective measure of diet, covering individual foods as well as different dietary patterns, in large-scale studies has great potential; this would for instance improve our understanding of the role of diet in long-term disease prevention and care in people with type 2 diabetes. The overarching aim of this study is to develop a framework from which dietary intake can be assessed, both as single foods and dietary patterns, in cohort studies among people with type 2 diabetes. This study is performed to assess which collection strategy best reflects long-term dietary intake and to weigh this up against feasibility and costs in large-scale studies.

NCT ID: NCT05884957 Completed - Diabetes Mellitus Clinical Trials

Role of Nitric Oxide in Diabetic Patients With Erectile Dysfunction

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Erectile dysfunction (ED) is defined as penile erection that is insufficient and unsustainable for a satisfactory sexual performance. The etiology of ED is multifactorial including chronic diseases such as hypertension, diabetes mellitus and coronary artery disease However, the main underlying cause is degenerative changes that result in endothelial dysfunction

NCT ID: NCT05878431 Completed - Diabetes Mellitus Clinical Trials

Foot Reflexology in Diabetic Patients With Neuropathic Pain

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

This study was carried out to determine the effect of foot reflexology applied to diabetic patients with neuropathic pain on their quality of life, hope and pain levels. This research, which was designed as a randomized controlled and experimental study, was conducted between January 2022 and December 2022. It was determined that foot reflexology application increased the quality of life and hope level of diabetic patients with neuropathic pain and decreased the level of pain.

NCT ID: NCT05875259 Completed - Hypertension Clinical Trials

A Clinical Trial Study to Evaluate the Pharmacokinetic Interaction and Safety Between BR1019-1 and BR1019-2 in Healthy Adult Subjects

Start date: May 13, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetic interaction and safety between BR1019-1 and BR1019-2 in healthy adult subjects.