View clinical trials related to Diabetes Mellitus, Type 2.
Filter by:NNC0519-0130 is a new medicine which may possibly help participants with type 2 diabetes. This study, will look into how safe the new medicine NNC0519-0130 is, and we will measure its concentrations in the blood and look at its effects. This study will last for a maximum of 22 weeks and Japanese and Non-Japanese male participants will be included.
Background and aim: Hyperinflammatory host response associated with diabetes mellitus significantly provokes periodontal tissue destruction. In this context, supporting the standard treatment of periodontitis in diabetics with host modulation agents is a current field of study. This clinical study aims to investigate the clinical efficacy of melatonin supplementation in non-surgical periodontal treatment in patients with Type 2 DM and periodontitis and its biological basis (clinical effectiveness) based on some basic markers. Material and method: In this randomized controlled and double-blind study, 27 of 55 patients with diabetic periodontitis underwent full mouth scaling and root planning (fmSRP) alone and 28 of them were administered melatonin (6 mg daily, for 30 days) in addition to fmSRP. The possible therapeutic contribution of melatonin was evaluated clinically and biochemically [gingival crevicular fluid (GCF) RANKL, OPG and MMP-8 and serum IL-1β levels] at 3 and 6 months.
American Diabetes Association and American Clinical Endocrinology American Association of Clinical Endocrinologists, treatment and care of individuals with diabetes in achieving their goals; regulation of nutrition, regulation of physical activity, pharmacological treatment, diabetes education, continuous monitoring and health checks should be done. emphasizes (3,4). Individuals with diabetes receive diabetes self-management education and support when necessary. they should. Diabetes self-management is the knowledge, skills and abilities necessary for the individual's self-care. It is defined as the facilitation process (4,5). Competent and skilled in self-management individuals with diabetes can improve their health outcomes. American Diabetes Association (ADA), diabetes self-management education necessary for the self-care of people with diabetes. take an individual-centered approach and make joint decisions to facilitate knowledge, skills and abilities It defines it as a process based on diagnosis, starting at the diagnosis stage and continuing (5). The goal of diabetes self-management is to introduce new skills and abilities that support diabetes patients' self-management goals. Developing behaviors and forming habits. General objectives of diabetes self-management education On the other hand, it enables individuals diagnosed with diabetes to make informed decisions, problem solving, personal care behavior, metabolic outcomes, health status and quality of life to improve (5). To strengthen the diabetes patient by providing self-management needs knowledge, skills and motivation about the disease. Counseling for nurses ability of the patient to adapt to his/her illness and self-care by doing and educating provides access (6). Coaching sessions to strengthen diabetes self-management and diabetes is applied. The coach is committed to maximizing the client's strengths, To ensure that it is used fully through continuous education, to be more effective, new to develop skills and activities, to be ready for new responsibilities, and to self-management. It is the person who provides the necessary motivation (7). Life Coaching with Diabetes, about lifestyle with diabetes professional life coaching practices, aiming at behavior change in approaches (ICF-International Coaching Federation) is based on the basic principles and principles. life with diabetes coaching is used to help people who have been diagnosed with diabetes make the necessary changes in life through coaching. to give practical applications. Walt Disney is a goal setting coaching exercise. The work consists of 6 steps. These steps it is as follows. 1. Detection of the subject and 3 anchor methods 2. Dreamer + Ground Anchor + Separator 3. Planner + Ground Anchor + Separator 4. Critic + Ground Anchor + Separator 5. Brainstorming 6. Metatest
Studies were found that a significant relationship between the severe periodontitis and increased CAVI values. While the exact mechanisms linking periodontitis, type 2 diabetes, and cardiovascular disease are not yet fully understood, it is clear that these diseases are interconnected. There are limited data in the literature evaluating the risk of atherosclerosis in diabetic individuals with periodontal disease. In our survey, we hypothesised that severe periodontitis may be a risk factor for the development of subclinical atherosclerosis among people with type 2 diabetes. Thus, we aimed to investigate the potential risk of subclinical atherosclerosis by using a new surrogate marker CAVI in severe periodontitis patients with short-term diabetes.
A qualitative study conducted in 2018 Exploring socio-cultural factors impacting adherence to type 2 diabetes therapy in rural Sargodha featured respondents who were primarily doctors, patients, and. Diet, exercise, and smoking were all variables. The void we investigators will fill will be comprised of several professionals assessing sleep and sedentary lifestyle. A book on anthropology published in 2021 shows the gap are still the same about sedentary life style. The investigators aim to determine lifestyle practices in relation to sedentary behaviour in different occupations & comparing which profession is prone to chronic diseases in accordance to lifestyle practices
The COVID-19 pandemic has caused a significant healthcare burden and remains a heavily researched disease entity. Originating in Wuhan, China in late 2019, SARS-CoV-2 has infected over 600 million individuals worldwide. ABO blood groups have been known to increase the human body's susceptibility to different pathogens, such as hepatitis B virus, MERS-COV, SARS-COV, norovirus, and malaria, to name a few. As such, the association of ABO blood groups and COVID-19 infection and disease severity has come into question.
AEYE-DS is a software device developed to increase compliance with diabetic retinopathy screening by automatically detecting more-than-mild diabetic retinopathy from digital funduscopic images using AI-based software. This study has been designed to validate the safety and efficacy of the device at primary care and other point of care sites.
The aim of study is impact of additional treatment with new antidiabetic drugs (semaglutide or empagliflozine) compared to control group in T1DM patients - impact on endothelial function measured by FMD and FPF, arterial stiffness - measured by PWV, inflammatory biomarkers, markers of oxidative stress and endothelial progenitor cells (CD 34+/VDRL2, CD 133+/VDRL2) and correlation with glucovariability or time in range, measured with CGM system.
This study will enroll patients ages 18 and over who have a diagnosis of diabetes, are undergoing an elective surgery under general anesthesia and 1) are taking a GLP-1 receptor agonist medication, or 2) not taking a GLP-1 receptor agonist medication. The patients will have a gastric ultrasound prior to surgery to measure any retained gastric contents. The primary goal is to assess the effect of subcutaneous injectable GLP-1 agonists on preoperative gastric volume in fasted, diabetic surgical patients.
Objective: The objective of this study was to evaluate the prevalence and impact of diabetes mellitus on the severity and mortality of COVID-19. Methods: Data of laboratory-confirmed hospitalized patients at the COVID-19 unit of Ibn El Jazzar University Hospital in Kairouan between September 2020 and August 2021 were analysed, in a cross-sectional study. The population was classified into two groups (COVID-19 patients with versus without diabetes). Primary outcomes were the overall length of hospital stay, the admission to the intensive care unit (ICU), and death.