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Dental Caries clinical trials

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NCT ID: NCT04329858 Not yet recruiting - Dental Caries Clinical Trials

the Antibacterial Effect of Zinc ,Silver and Fluoride

Start date: July 15, 2021
Phase: N/A
Study type: Interventional

natural teeth will be filled with the 3 different material then the dentin sample will be collected ,bacterial culture and elementary analysis will be done

NCT ID: NCT04303767 Not yet recruiting - Caries,Dental Clinical Trials

The Effect of Casein Phosphopeptide Amorphous Calcium Phosphate on Affected Dentine

Start date: March 1, 2020
Phase: Phase 2
Study type: Interventional

Teeth selected for intervention with Atraumatic Restorative Treatment will receive Glass Ionomer restorations (control) or MI varnish (test) before receiving the Glass Ionomer restoration

NCT ID: NCT04285931 Not yet recruiting - Dental Caries Clinical Trials

Prevelance of Dental Caries in Agroup of Egyption Children Using Caries Assessment Spectrum and Treatment

Start date: March 2020
Phase:
Study type: Observational [Patient Registry]

To explore the prevalence of dental caries in Egyptian children aged from 6 to 9 years oldusing CAST index and DMFT index

NCT ID: NCT04274959 Not yet recruiting - Clinical trials for Posterior Ceramic Onlays

Functional Evaluation of Ceramic Onlay Restorations With Different Preparation Designs

Start date: February 20, 2020
Phase: N/A
Study type: Interventional

Tooth preparation designs for posterior ceramic restorations have been based on traditional cast metal restoration designs, but with more occlusal tooth reduction and with a slightly increased taper. These preparations may involve the removal of considerable tooth structure. As more structure is removed, higher tooth strain and lower fracture resistance may occur.5 The increased tooth structure loss may increase cuspal flexure, thereby reducing the tooth fracture resistance, or open the restoration-tooth interface . However, it has been demonstrated that cusp recovery results in fewer failures, likely increasing the longevity of posterior ceramic restorations. Recently, minimally invasive cavity preparations for posterior indirect restorations were demonstrated to present the benefit of conservation of tooth structure, as well as improved stress distribution. However, the performance of posterior restoration is also material dependent. Due to the continuous advancements in dental ceramics and innovative manufacturing techniques. The aim of this study is to evaluate the clinical functional performance of ceramic onlay restorations with butt joint preparation design and compare them to shoulder preparation design.

NCT ID: NCT04245787 Not yet recruiting - White Spot Lesion Clinical Trials

Remineralization Potential of Curodont Repair Flouride Plus Versus CPP-ACP in Management of White Spot Lesions: Randomized Clinical Trial

Start date: February 2020
Phase: N/A
Study type: Interventional

The goal of modern dentistry is to manage non-cavitated caries lesions non- invasively through re-mineralization process to prevent the disease progression and improve aesthetics, strength, and function. Re-mineralization is defined as the process that supplies calcium, phosphate and flouride ions from an external source to the tooth to convert ion deposition into crystal voids in demineralized enamel. White spot lesions should be managed using a multifactorial approach. The most important strategy is to prevent demineralization and biofilm formationand use of methodologies for remineralization of lesions . Self-assembling peptide (P11-4) has shown great potential for natural repair of early caries lesions through emerging biomimetic re-mineralization properties. (Takahashi Fet al in 2015) This peptide forms a 3D matrix within demineralized carious lesions areas, which enables novo hydroxyapatite crystal formation facilitating the so-called guided enamel regeneration of the lost enamel structure. The peptide has shown encouraging results as a scaffold for enamel regeneration

NCT ID: NCT04183777 Not yet recruiting - Pain Clinical Trials

Assessment of the Age, Reasons, Oral Health Status and Dental Treatment Needs of Children in Their First Dental Visit

Start date: March 1, 2020
Phase:
Study type: Observational

to asses the age, reasons, oral health status and dental treatment needs of children in their first dental visit.

NCT ID: NCT04096209 Not yet recruiting - Badly Decayed Teeth Clinical Trials

Immediate Implant Placement in the Esthetic Zone With and Without Using Autogenous Mixed With Xenograft

Start date: September 30, 2019
Phase: N/A
Study type: Interventional

Xenografts are graft materials derived from the inorganic portion of animal bones; the most common source is bovine the removal of the organic component are processed to remove their antigenicity, while the remaining inorganic components provide a natural matrix as well as an excellent source of calcium. The disadvantage of xenografts is that they are only osteoconductive and the resorption rate of bovine cortical bone is slow. However leaving the jumping gap empty has been the gold standard for immediate implantation as the formed blood clot will allow bone fill in that area.

NCT ID: NCT04052789 Not yet recruiting - Clinical trials for Badly Decayed Teeth andTeeth Restored With Large Filling Restorations and Endodontically Treated Teeth and Malformed Teeth and Malposed Teeth

Clinical Evaluation of Internal Fit of Milled BioHPP Polyetheretherketone (PEEK) - Based Versus Zirconia-Based Single Crowns

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

All ceramic crowns are indicated in case of mild to moderate discoloration, restoration of traumatized or fractured teeth and abnormal tooth anatomy. The success of dental restorations is determined by four main factors: biocompatibility, aesthetic value, resistance to fracture and marginal adaptation. . An inadequate marginal fit may compromise the longevity of the restoration since cement film exposure to the oral environment can lead to its dissolution . . Polyetheretherketone (PEEK) is a polymer that has many potentials uses in dentistry. Polyetheretherketone (PEEK) can be used to support fixed dental prostheses. However, information about physio mechanical characterization is still scarce. Aim of the study: - The aim of this study is to evaluate the internal fit of milled BioHPP PEEK-based versus zirconia-based single crowns.

NCT ID: NCT04033263 Not yet recruiting - Dental Caries Clinical Trials

Maintaining Oral Health With Bio-products

Start date: September 2024
Phase: N/A
Study type: Interventional

This study will follow a randomised, double-blind, cross-over design. Participants will use mouth rinses containing plant extracts and/or fluoride, as well as a mouth rinse containing only water (placebo). They will use oral appliances containing sterilized enamel and dentine slabs, which will be later collected for analyses. The cross-over design will allow participants to use all rinses, allowing for a comparison between the rinses within each individual.

NCT ID: NCT04032210 Not yet recruiting - Clinical trials for Prevention of Dental Caries

The Influence of Preventive Regimens Containing Different Toothpastes on Caries Risk of High Risk Patients: A Randomized Clinical Trial

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

66 Participants will be divided into three groups according to the tested regimen (A), where (A1) represents participants will be exposed to regimen including dual zinc plus arginine based toothpaste (Colgate total), (A2) represents participants will be exposed to regimen including zinc based toothpaste (Crest complete) and (A3) represents control group where participants will be used fluoride based toothpaste (Signal). The study will be carried over a period of one year, assessment of cariogram will be done in two visits: first visit (baseline: T0) and second visit (after 3 months: T3) . In addition assessment of DMF scores will be done in four visits: first visit (baseline: T0), second visit (after 3 months: T3), third visit (after 6 months: T6) and final visit (after 12 months: T12) to obtain the required data