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Dental Caries clinical trials

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NCT ID: NCT04032184 Not yet recruiting - Clinical trials for Prevention of Dental Caries

Effectiveness of Different Preventive Regimens in Cariogram Parameters and DMF Scores of High Caries Risk Patients: A Randomized Control Trial

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

66 Participants will be divided into three groups according to the tested regimen (A), where (A1) represents participants exposed to fluoride toothpaste, (A2) represents participants exposed to regimen including fluoride toothpaste and chlorhexidine mouthwash and (A3) represents participants exposed to regimen including fluoride toothpaste, chlorhexidine mouthwash and MI fluoride varnish. The study will be carried over a period of one year, assessment of cariogram will be done in two visits: first visit (baseline: T0) and second visit (after 3 months: T2). In addition assessment of DMF scores will be done in four visits: first visit (baseline: T0), second visit (after 3 months: T1), third visit (after 6 months: T2) and final visit (after 12 months: T3) to obtain the required data

NCT ID: NCT04030117 Not yet recruiting - Clinical trials for Class II Dental Caries

Class II Restoration Using Bioactive Restorative Material vs Polyacid Modified Composite Resin in Primary Molars

Start date: September 2019
Phase: N/A
Study type: Interventional

Successful restoration of cavities in primary molars can be considered challenging. It is different from restoring cavities in permanent molars because factors such as the level of co-operation of the child and the handling properties and setting time of the restorative material will have some influence on the success rate of the restoration. The ideal requirements that a filling material should possess include that it bears the occlusal force, withstands the acidic and bacterial attack, survives in the oral environment in addition to being biocompatible with the oral tissues. In an attempt to achieve this idealism, a new class of restorative materials known as "bioactive materials" has been developed. The concept of bioactive materials was introduced in 1969 and later defined as "one that elicits a specific biological response at the interface of the material which results in the formation of a bond between tissues and the material." An example of bioactive materials is ACTIVAâ„¢ BioACTIVE (Pulpdent, USA). These materials are ionic composite resins which combine the biocompatibility, chemical bond and the ability to release fluoride of glass ionomers with the mechanical properties, esthetic and durability of composite resins. Compomer is widely accepted as a standard restorative material for primary dentition for Class I and II cavities. Its range of success rate in Class II restorations in primary molars is 78-96%. Many randomized clinical trials have reported comparable clinical performance to composite resin with respect to color matching, marginal discoloration, anatomical form, marginal integrity and secondary caries. In comparison to glass ionomer and Resin Modified Glass Ionomer, compomers tend to have better physical properties in the primary dentition. However, their cariostatic properties didn't differ significantly from those materials.

NCT ID: NCT04017884 Not yet recruiting - White Spot Lesion Clinical Trials

Evaluation of Remin Pro Forte Versus Remin Pro on Treatment of White Spot Lesions Post Orthodontic Treatment

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

randomized clinical trial to evaluate caries regression, the change in colour and mineral content of the demineralized enamel after treatment with Remin Pro Forte paste (fluoride, hydroxyapatite, xylitol, ginger, and curcuma) and Remin pro cream which contains (fluoride, hydroxyapatite, xylitol) remineralizing agents with the null hypothesis that Remin Pro forte will have the same clinical performance as Remin Pro in remineralizing white spot lesions post-orthodontic treatment.

NCT ID: NCT03990935 Not yet recruiting - White Spot Lesions Clinical Trials

Remineralization Potential of Ginger and Rosemary Herbals Versus Sodium Fluoride in Treatment of White Spot Lesions

Start date: July 2019
Phase: N/A
Study type: Interventional

To evaluate the effectiveness of ginger and rosemary herbals versus sodium fluoride in remineralization of incipient enamel caries.

NCT ID: NCT03989687 Not yet recruiting - Clinical trials for Dental Caries in Children

Clinical Retention of Glass Ionomer Sealants Placed With and Without Rubber Dam: a Comparative Analysis

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

A comparative analysis of glass ionomer sealant placed on permanent molars with and without a rubber dam to assess the retention over a 2 year period.

NCT ID: NCT03976583 Not yet recruiting - White Spot Lesion Clinical Trials

Remineralization Potential of Pearl Powder Compared to CPP-ACP on Enamel White Spot Lesions

Start date: September 1, 2019
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the remineralization potential of pearl powder on early ('white spot') lesions in enamel in orthodontic patients compared to casein phosphopeptide-amorphous calcium phosphate.

NCT ID: NCT03973554 Not yet recruiting - Clinical trials for White Spot Lesion of Tooth

Caries Prevention Potential of Pearl Powder Versus CPP-ACP on Enamel White Spot Lesions

Start date: October 30, 2019
Phase: Phase 2
Study type: Interventional

to evaluate the caries prevention potential of pearl powder against CPP-ACP in enamel white spot lesions.

NCT ID: NCT03966378 Not yet recruiting - Dental Caries Clinical Trials

Reminerlization Potential of GSE Gel versusCPP-ACP in Carious White Spot Lesions in Post Orthodontic Patients

Start date: October 3, 2019
Phase: N/A
Study type: Interventional

Assess the effectiveness of applying grape seed extract (GSE) gel versus casein phosphopeptide-amorphous calcium phosphate (MI) paste on remineralization of white spot lesion (WSLs) in post orthodontic patients.

NCT ID: NCT03963791 Not yet recruiting - Dental Caries Clinical Trials

Remineralization Effect of Eggshell Powder on Post-orthodontic White Spot Lesions Compared to CPP-ACP

REEPP-WSC
Start date: October 5, 2019
Phase: N/A
Study type: Interventional

This research is conducted to compare the remineralization efficacy of eggshell powder gel and CPP-ACP (MI paste) on post-orthodontic white spot lesions.

NCT ID: NCT03930927 Not yet recruiting - Clinical trials for White Spot Lesion of Tooth

Effect of Self Assembling Peptide on White Spot Lesion

regeneration
Start date: May 1, 2019
Phase: Early Phase 1
Study type: Interventional

During re-mineralization of white spot lesion, Will biomimetic self-assembling peptides improve the re-mineralizating effect of the post orthodontic white spot lesion compared to fluoride-based delivery systems?