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NCT ID: NCT05895279 Completed - Prostate Carcinoma Clinical Trials

Assessment of Research Digest Impact for Minority With Prostate Cancer, MiCAP Phase III Study

MiCaP
Start date: August 2, 2021
Phase: N/A
Study type: Interventional

This phase III trial determines how well the Minority Prostate Cancer (MiCaP) Research Digest works in providing information to black men about the latest prostate cancer research. MiCaP Research Digest may be an effective method to help people learn about prostate cancer.This goal of this trial is to create educational programming that helps Black men make informed decisions about their prostate healthcare since Black men are diagnosed with prostate cancer more than any other race or ethnicity.

NCT ID: NCT05895266 Completed - Healthy Volunteer Clinical Trials

A Study to Assess Drug-Drug Interaction Between ABBV-903 and Midazolam in Adult Healthy Volunteers

Start date: June 23, 2023
Phase: Phase 1
Study type: Interventional

The main objective of this study is to assess the drug-drug interaction and pharmacokinetics of ABBV-903 and Midazolam in healthy adult participants.

NCT ID: NCT05895084 Completed - Brain Injuries Clinical Trials

Neural Markers of Balance in Adults With Brain Injury

Start date: August 30, 2021
Phase: N/A
Study type: Interventional

The feasibility study is designed to assess the feasibility of conducting a group yoga intervention and acquiring neuroimaging data in adults with chronic brain injury.

NCT ID: NCT05894928 Completed - Healthy Clinical Trials

A Study to Evaluate the Effect of Cholestyramine on LOXO-783 in Healthy Participants

Start date: June 7, 2023
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to conduct blood tests to measure how much LOXO-783 is in the bloodstream and how the body handles and eliminates LOXO-783 when administered alone or in combination with cholestyramine in healthy participants. The study will also evaluate the safety and tolerability of LOXO-783 with and without cholestyramine. Participation could last up to 63 days including screening period.

NCT ID: NCT05894577 Completed - Covid19 Clinical Trials

ACTIV-6: COVID-19 Study of Repurposed Medications - Arm F (Montelukast)

Start date: January 27, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of repurposed medications (study drug(s) in reducing symptoms of non-hospitalized participants with mild to moderate COVID-19. Participants will receive either study drug or placebo. They will self-report any new or worsening symptoms or medical events they may experience while taking study drug or placebo. This study is intended to be all remote with no in person visits, unless the study team feels it is in the best interest of a participant to see them in person. Prior and current drug arms are listed on clinicaltrials.gov and will be updated with the activation of any new drug arms. Each study arm will also have its own clinicaltrials.gov entry and will include "Pro00107921" in the Unique Protocol ID.

NCT ID: NCT05894564 Completed - Covid19 Clinical Trials

ACTIV-6: COVID-19 Study of Repurposed Medications - Arm E (Fluvoxamine 100)

Start date: August 25, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of repurposed medications (study drug(s) in reducing symptoms of non-hospitalized participants with mild to moderate COVID-19. Participants will receive either study drug or placebo. They will self-report any new or worsening symptoms or medical events they may experience while taking study drug or placebo. This study is intended to be all remote with no in person visits, unless the study team feels it is in the best interest of a participant to see them in person. Prior and current drug arms are listed on clinicaltrials.gov and will be updated with the activation of any new drug arms. Each study arm will also have its own clinicaltrials.gov entry and will include "Pro00107921" in the Unique Protocol ID.

NCT ID: NCT05894538 Completed - Covid19 Clinical Trials

ACTIV-6: COVID-19 Study of Repurposed Medications - Arm D (Ivermectin 600)

Start date: February 16, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of repurposed medications (study drug(s) in reducing symptoms of non-hospitalized participants with mild to moderate COVID-19. Participants will receive either study drug or placebo. They will self-report any new or worsening symptoms or medical events they may experience while taking study drug or placebo. This study is intended to be all remote with no in person visits, unless the study team feels it is in the best interest of a participant to see them in person. Prior and current drug arms are listed on clinicaltrials.gov and will be updated with the activation of any new drug arms. Each study arm will also have its own clinicaltrials.gov entry and will include "Pro00107921" in the Unique Protocol ID.

NCT ID: NCT05893862 Completed - Schizophrenia Clinical Trials

A Study To Evaluate The Effect Of A Supratherapeutic Dose Of MK-8189 On The QTc Interval In Participants With Schizophrenia (MK-8189-019)

TQT
Start date: June 26, 2023
Phase: Phase 1
Study type: Interventional

The primary purpose of this study to evaluate the effect of a supratherapeutic dose of 80 mg MK-8189 on the QT interval corrected for heart rate (QTc interval) and to assess the safety and tolerability of multiple once-daily doses of MK-8189 in participants with schizophrenia. The primary hypothesis is that the administration of an 80 mg MK-8189 dose on Day 2 does not prolong the QTc interval to a clinically significant degree. Specifically, the true mean difference (MK-8189 - placebo) in QTc change from baseline is less than 10 milliseconds (msec).

NCT ID: NCT05893043 Completed - Healthy Volunteers Clinical Trials

A Study of Multiple Ascending Doses of GSBR-1290 in Japanese and Non-Japanese Healthy Participants

Start date: April 24, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess safety and tolerability of multiple oral doses of GSBR-1290 (capsule) in healthy adult Japanese participants compared to non-Japanese participants.

NCT ID: NCT05892757 Completed - Healthy Volunteers Clinical Trials

Study to Assess Adverse Events and Compare How Oral Ubrogepant and Oral Atogepant Moves Through the Body of Healthy Female Adult Volunteers

Start date: July 11, 2023
Phase: Phase 1
Study type: Interventional

This study will assess adverse events and compare how ubrogepant and atogepant tablets move through the body of healthy adult lactating female participants. Ubrogepant and atogepant are approved drugs for treatment of migraine in adults. Participants will be assigned to one of the 2 treatment arms to receive atogepant or ubrogepant. Approximately 24 healthy adult lactating female participants will be enrolled at 3 sites in the United States Participants will receive oral tablets of ubrogepant or atogepant on Day 1 and will be followed for 30 days.