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NCT ID: NCT04820348 Completed - Depression Clinical Trials

Assessing Adherence to Digital Health Technologies Among Hispanic/Latino Adults With or At Risk of Type 2 Diabetes:

Start date: April 9, 2021
Phase:
Study type: Observational

In an effort to personalize medical care, novel approaches have been used to categorize sub-populations of patients with type 2 diabetes (T2D). These are based on biological and genetic variables, allowing identification of clusters with significantly different clinical characteristics and risks of complications that may be more amenable to targeted and precise therapeutic interventions. Increasingly, wearable and other digital health technologies have the potential to capture additional and objective information to support personalized medicine but at present underserved populations have largely been excluded from clinical trials incorporating digital health. With this study, the Investigators aim to build on prior work using specially trained community health workers ("Community Scientists") to support engagement with an underserved population and to encourage adherence to using wearables and other digital health technologies. In the US, this is especially imperative for the Hispanic/Latino population, which is at high risk for T2D and associated complications.

NCT ID: NCT04820218 Completed - Myopia Clinical Trials

At-home Testing Refraction Results With Best Corrected Visual Acuity (BCVA) Outcomes in Adults

Start date: April 21, 2021
Phase: N/A
Study type: Interventional

This study is aimed at examining the BCVA from try-on glasses constructed from measurements from the EyeQue VisionCheck.

NCT ID: NCT04820192 Completed - Clinical trials for Post-Concussion Syndrome

Craniosacral Therapy for Concussion Symptoms

Start date: January 15, 2018
Phase:
Study type: Observational

This study investigated the utilization of CranioSacral Therapy (CST) in patients with Post-Concussion Syndrome (PCS) and capture patient-reported perceptions of their lived experiences of treatment effect upon their symptoms. The first part part was a 10 year chart review of patients who sought out CST to capture data from the medical records. The second part was an anonymous post treatment survey.

NCT ID: NCT04820153 Completed - Clinical trials for Neurological Disorder

Monitoring Physical Activity in Hispanic Women With Chronic Neurological Disorders

Start date: March 26, 2019
Phase: N/A
Study type: Interventional

The primary goal of this proposal is to demonstrate the feasibility of using a Fitbit charge to monitor and promote physical activity in a diverse population of Hispanic women with chronic neurological disorders. Hispanic women will also receive behavioral coaching using a Lifestyle Redesign approach to enhance physical activity in their daily lives. The secondary goal of this proposal is to investigate whether changes in physical activity are associated with (i) quality of life including perception of health and well- being and (ii) frequency of hospital and county clinic visits.

NCT ID: NCT04819906 Completed - Clinical trials for Prolonged QTc Interval

Effect of Estetrol Monohydrate (E4) on QTc Interval

Start date: March 9, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is: - to evaluate if E4 has any effect on how the heart beats when a single dose is given at two different dose levels; - to determine the ability to detect small changes in how the heart beats using a positive control: moxifloxacin, a quinolone antibiotic approved by the FDA as a positive control in thorough QT (TQT) studies; - to assess the safety and tolerability of a single dose of E4 administered at two different dose levels; - to measure the amount of study drug in the blood stream and how long it takes for the body to eliminate it (Pharmacokinetics) after administration.

NCT ID: NCT04819776 Completed - Bipolar I Disorder Clinical Trials

Evaluation of Efficacy and Safety of Iloperidone in the Acute Treatment of Manic or Mixed Episodes Associated With Bipolar I Disorder

Start date: March 22, 2021
Phase: Phase 3
Study type: Interventional

The aim of this study is to investigate the efficacy, safety, and tolerability of iloperidone compared with placebo in treating acute manic or mixed episodes associated with Bipolar I Disorder.

NCT ID: NCT04819646 Completed - Inflammation Clinical Trials

Evaluate the Effects of a Marine Lipid Oil Concentrate Formulation on Inflammation/Discomfort

Start date: January 7, 2021
Phase: N/A
Study type: Interventional

The purpose of the study is to assess the efficacy and safety of a Marine Lipid Oil Concentrate formulation on inflammation/discomfort and overall well-being in male and female subjects who are generally healthy

NCT ID: NCT04819594 Completed - Stress Levels Clinical Trials

The Effects of Aromatherapy on the Stress Levels of Nurses Working in an Urban, Safety-Net Community Hospital

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

Parkland Hospital inpatient nursing staff will be the focus of this study. This project aims to investigate the use of lavender on the stress levels associated with the nursing role. Nurses will wear the Elequil aromatabs ® over a four-hour period and a post survey will be given to assess root cause of stress and changes related to intervention.

NCT ID: NCT04819581 Completed - Healthy Clinical Trials

Pharmacokinetic Study of SP-103 in Healthy Adult Human Subjects

Start date: August 3, 2019
Phase: Phase 1
Study type: Interventional

This study will assess the systemic exposure and pharmacokinetic parameters of SP-103 topical system following one, two, or three topical system applications and compare to the pharmacokinetics of ZTlido.

NCT ID: NCT04819373 Completed - Tumor, Solid Clinical Trials

BDB001-201: A Clinical Study of BDB001 in Patients With PD-(L)1 Refractory Solid Tumors

Start date: August 30, 2021
Phase: Phase 2
Study type: Interventional

BDB001-201 is a multi-center, open-label, Phase II clinical trial to evaluate the efficacy and safety of BDB001 in the treatment of subjects with advanced solid tumors that have progressed on anti-PD-1 or anti-PD-L1 mAb treatment.