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NCT ID: NCT04882813 Completed - Clinical trials for Chronic Kidney Disease

Replication of the DAPA-CKD (Chronic Kidney Disease) Trial in Healthcare Claims Data

Start date: December 13, 2020
Phase:
Study type: Observational

Investigators are building an empirical evidence base for real world data through large-scale replication of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.

NCT ID: NCT04882800 Completed - Hearing Loss Clinical Trials

Evaluation of Extended Wear Technology

Start date: April 8, 2021
Phase: N/A
Study type: Interventional

Evaluating the efficacy and effectiveness of an advancement in the fitting characteristics of extended wear technology with the commercially available device as a comparator.

NCT ID: NCT04882631 Completed - Healthy Volunteers Clinical Trials

A Study to Evaluate the Skin Irritation Potential of PBI-100 Topical Cream in Healthy Participants

Start date: April 12, 2021
Phase: Phase 1
Study type: Interventional

This is an open-label, single-arm, randomized, evaluator-blinded repeat insult patch testing (RIPT) study wherein test product is applied under an occlusive dressing to the upper back or arm continuously and repeatedly to the same site for a period of 21 days.

NCT ID: NCT04882501 Completed - Clinical trials for Nausea, Postoperative

Effects of Aromatherapy on Nausea Levels

Start date: April 19, 2021
Phase: N/A
Study type: Interventional

Aromatherapy is the therapeutic use of essential oils from plants for the improvement of physical, emotional, and spiritual well-being. Healthcare providers play an important role in improving the care of patients with nausea. Aromatherapy is a complementary therapy that may help with post-operative nausea in the adult post-operative bariatric patient population. The purpose of this study is to evaluate the effects of aromatherapy intervention on nausea levels with post-operative bariatric patients once they are on the surgical unit.

NCT ID: NCT04882384 Completed - Hip Fractures Clinical Trials

Pericapsular Nerve Group Block for Hip Fractures

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

This will be a feasibility study to see if it feasible to perform the Pericapsular Nerve Group Block for hip fractures in the Emergency Department. In addition, we will look at the efficacy of the block in these 10 patients by measuring pain scores at pre-determine time points for 16 hours.

NCT ID: NCT04882319 Completed - Clinical trials for Osteoarthritis of the Knee

Irritation and Sensitization Study of HP-5000 Topical System

Start date: June 3, 2021
Phase: Phase 1
Study type: Interventional

This study will assess skin irritation and sensitization for HP-5000 patch in healthy subjects.

NCT ID: NCT04882150 Completed - Clinical trials for Healthy Participants

A Study to Determine the Safety, Drug Levels and Drug Effects of BMS-986196 and Food and Formulation Effects on Relative Absorption Healthy Participants

Start date: May 27, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to characterize the safety, tolerability, drug levels and drug effects of BMS-986196 in healthy participants. In addition, an evaluation of food and formulation effects on BMS-986196 absorption will be performed.

NCT ID: NCT04882124 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Study of Effect of CSJ117 on Symptoms, Pharmacodynamics and Safety in Patients With COPD

Start date: September 24, 2021
Phase: Phase 2
Study type: Interventional

This is a Phase 2 study in patients with chronic obstructive pulmonary disease (COPD) to assess the efficacy, pharmacodynamics (PD), pharmacokinetics (PK), and safety of two dose levels of CSJ117 in comparison to placebo. For this, the impact of CSJ117 on disease symptom burden and lung function will be explored.

NCT ID: NCT04882111 Completed - Cancer Clinical Trials

ALIGN Intervention in Patients With Advanced Cancer Discharging to a SNF

ALIGN
Start date: September 28, 2020
Phase: Early Phase 1
Study type: Interventional

This is a single arm, pre-post, pilot study assessing the feasibility and acceptability of the ALIGN intervention in metastatic adult cancer patients discharging to local area SNFs.

NCT ID: NCT04881942 Completed - Tobacco Use Clinical Trials

Characterization of Selected Aerosol Constituents Levels in the Exhaled Breath of Adult e-Vapor Users

Start date: March 27, 2017
Phase: N/A
Study type: Interventional

This is an open-label, 4-way crossover study designed to estimate the nicotine, glycerin, propylene glycol, menthol, formaldehyde, acetaldehyde, and acrolein levels in exhaled breath samples during use of four MarkTen® XL e-vapor products. The study will enroll approximately 32 adult e-vapor-using subjects at one site in the United States in High Point, NC.