There are about 173942 clinical studies being (or have been) conducted in United States. The country of the clinical trial is determined by the location of where the clinical research is being studied. Most studies are often held in multiple locations & countries.
The purpose of this study is to determine whether hydrocortisone biases formation of alcohol-related memories to potentiate drinking.
The purpose of the study is to evaluate the Mechanism Of Action (MOA) of ruxolitinib cream in vitiligo by assessing the change in biomarkers.
This study aims to develop and evaluate an intervention to reduce enacted stigma in healthcare settings aimed at people living with HIV (PLWH) and men who have sex with men (MSM) in China. Enacted stigma will be measured using a quality of care score collected through unannounced standardized patient (SP) visits to consenting providers in sexual health clinics.
The aim of the current project are is examine the incremental predictive utility of the MMPI-2-RF-EX validity scales in detecting simulated underreporting of suicide risk on the MMPI-2-RF-EX and other self-report measures of suicide risk in 150 military Veterans experiencing past-month death or suicidal ideation.
Background: Influenza (flu) is a contagious respiratory illness. It is caused by influenza viruses that infect the nose, throat, and sometimes the lungs. Vaccines are given to teach the body to prevent or fight infection. Researchers want to study a new vaccine to prevent the seasonal flu. Objective: To see if the FluMos-v1 vaccine is safe and how the body responds to it. Eligibility: Healthy adults ages 18-50 who received at least one licensed flu vaccine from 2016 through the 2019-2020 influenza season. Design: Participants will be screened through a separate protocol. Participants will be tested for COVID-19. They may have a pregnancy test. Participants will receive the FluMos-v1 vaccine or the Flucelvax vaccine. It will be injected in the upper arm. Participants will complete a diary card for 7 days. They will record any symptoms they have. They will be given a thermometer to check their temperature. They will also be given a ruler to measure any skin changes at the injection site. Participants will have about 10 study visits. They will be asked how they are feeling and if they have taken any medications. They will have blood drawn. Participants will have oral mucosal samples collected using a thin swab. They may have nose and throat secretions collected using a thin swab. Some participants will have optional apheresis. Blood will be removed through a needle in a vein in one arm. A machine will separate the white blood cells. The rest of the blood will be returned through a needle in a vein in the other arm. Participation will last for 40 weeks.
This is a 4 dose study with 124 participants (7 adults ,117 children). Adults are considered to be participants 18 years of age or older. Participants are going to be enrolled based on conditions that make them immunocompromised. Participants are going to be followed up for 6 months after dose 4, and each participant is projected to be on the study for approximately 15 months. This study will be conducted in the United States, Brazil, Germany and Mexico.
This study tested the effects of a botanical blend to a caffeine and a placebo condition on 1) self-reported alertness, anxiety, and headaches 2) multiple measures of attention 3) physical performance and 4) stress biomarkers.
Improving the health literacy of adolescents and increasing the success of transitions to adulthood from foster care are two defined Healthy People 2030 public health priorities. Skills to promote health literacy and independent living are often lacking in adolescents in foster care and young adults who have aged out of care. Frequent placement changes, no permanent home, lack of trust in adults and systems of care prevent the development of a strong support system for transitioning to adulthood from foster care, which can result in lack of access to personal health information, complicated identity documents, and disconnected child welfare, health care and community resources. These factors limit the ability to transition to adulthood successfully, drive disparities in health outcomes, and may explain lack of educational attainment and career development for young adults formerly in care. Successful transitions to independent living are unattainable unless barriers are addressed with a multidisciplinary, community-based approach. The Rees-Jones Center for Foster Care Excellence at Children's Health and the Krissi Holman Family Resource Library at Children's Health recognized the unique needs of adolescents in foster care and young adults formerly in care (AYAFC) as they transition to independent living. We developed a partnership with community agencies (Empowering Youth Taskforce) that support these youth in the areas of child welfare (TX Department of Family and Protective Services), education (UNT PuSH Program), career development and housing support (TRAC at City Square, Zoie's Place), legal support (SMU Dedman Law School), and others, to increase AYAFC health literacy, access to health care, and awareness and use of available community resources. Frequent placement changes and unstable housing make it difficult for AYAFC to keep their health information, identity records and personal documents together, which is critical for accessing health services, enrolling in health insurance, and maintaining wellness. Since many have access to a smart phone, using technology is one way to promote adolescent health and wellness. An app is a possible solution to address many of the barriers that impede successful transition to independent living. The goal of this project is to engage AYAFC and stakeholders who support these young people throughout North Texas to collaboratively design an app to support the transition from foster care to adulthood. This project will utilize a mixed methods approach to inform the transition process while addressing both individual and systems level barriers to increase the success of AYAFC's transition to independent living. This project builds upon work done by a multidisciplinary community task force led by the Principal Investigator, and the development of an adolescent transition process at the Rees-Jones Clinic. Community partners are fully engaged in the design of the intervention and will be involved in AYAFC and stakeholder recruitment, data analysis, and interpretation of the results.
This study is to see if applying green and violet low level laser light to the neck and shoulders can help to reduce pain in the neck and shoulders.
The purpose of this study is to determine whether the Erchonia HLS Laser is effective in the treatment of irritability associated with autistic disorder in children and adolescents aged five (5) to twelve (12) years.