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NCT ID: NCT06361485 Recruiting - Low Back Pain Clinical Trials

Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain

Start date: March 25, 2024
Phase: Phase 1
Study type: Interventional

This is a Pilot Study that is an open label, prospective, non-controlled study in which the safety and feasibility of Wharton's Jelly (WJ) allograft will be evaluated in 100 participants suffering with low back pain.

NCT ID: NCT06361303 Recruiting - Infant Death Clinical Trials

The Happiest Baby, Inc. SNOO Postmarket Surveillance Study

Start date: November 29, 2023
Phase:
Study type: Observational

This postmarket surveillance study will evaluate the safety of the SNOO Smart Sleeper Bassinet when used for infants who are at high risk for Sudden Unexpected Infant Death (SUID). This study will survey 1000 caregivers of high-risk infants to examine the frequency of death or serious injury occurring in the SNOO Bassinet.

NCT ID: NCT06361056 Recruiting - Breast Cancer Clinical Trials

Mobile Health App to Promote Participation of Black Women in Breast Cancer Clinical Trials

Start date: May 2, 2022
Phase: N/A
Study type: Interventional

This study explores the overall feasibility, impact, and satisfaction of using the "mHealth app" on clinic workflow for Black or African American women diagnosed with breast cancer. The "mHealth app" which can be used as a platform to share clinical trial education and communication, was created and tested in previous steps of this study.

NCT ID: NCT06360822 Recruiting - Lung Cancer Clinical Trials

Increasing Equity in Lung Cancer Screening

LUCARE
Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The overall objective of this mixed methods study is to: 1) Refine the Emergency Department Lung Cancer Screening (ED-LCS) intervention using qualitative interviews among key stakeholders; 2) pilot test the ED-LCS intervention evaluating the intervention efficacy, acceptability, and feasibility; and 3) provide an in-depth description of stakeholders' experiences with the ED-LCS intervention for future refinement.

NCT ID: NCT06360718 Recruiting - Leukemia Clinical Trials

Effects of Using a Storybook, to Explain Leukemia to Children Versus the Standard Child Life Intervention, on Parental Stress.

Start date: February 3, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to measure the effects of using a storybook versus standard child life intervention with parents of children newly diagnosed with leukemia on parental stress. The main questions it aims to answer are: - What effect will the storybook have on parent/legal guardian stress at three timepoints: baseline, discharge, and follow up? - Will this storybook impact parent/legal guardian comfort levels and improve their child's understanding? Participants will be asked to complete surveys at three timepoints, prior to and following child life intervention and about 3.5 months later. During child life interventions, participants will receive resources and support to explain leukemia to their school aged, 3-16-year-old, child (patient or sibling). Researchers will compare Intervention and Control Groups to see if parental stress is lower in those who received the storybook in addition to the standard child life intervention versus the standard child life intervention alone.

NCT ID: NCT06360705 Recruiting - Clinical trials for Vulvar Lichen Sclerosus

StrataMGT for the Treatment of Vulvar Lichen Sclerosus

Start date: April 2024
Phase: N/A
Study type: Interventional

This study is designed to evaluate the efficacy and safety of StrataMGT for the treatment of vulvar lichen sclerosus.

NCT ID: NCT06360562 Recruiting - Anxiety Disorders Clinical Trials

Reconnecting to Ourselves and Others in Virtual Meetings (ROOM)

Start date: September 15, 2020
Phase: N/A
Study type: Interventional

This study aimed to determine the feasibility and acceptability of delivering Resilience Training in multi-user virtual reality.

NCT ID: NCT06360419 Recruiting - Clinical trials for Major Depressive Disorder

Progressing TAAR-1, Dopamine, and Norepinephrine in Depression Using Solriamfetol

PARADIGM
Start date: March 18, 2024
Phase: Phase 3
Study type: Interventional

PARADIGM (Progressing TAAR-1, Dopamine, and Norepinephrine in Depression Using Solriamfetol) is a Phase 3, randomized, double-blind, placebo-controlled, multicenter trial to assess the safety and efficacy of solriamfetol for the treatment of major depressive disorder (MDD) in adults.

NCT ID: NCT06360367 Recruiting - Diet, Healthy Clinical Trials

mHealth to Improve Diet Quality Among Early Adolescents in SNAP-Ed in Hawaii

Start date: April 23, 2024
Phase: N/A
Study type: Interventional

The goal of this 8-week clinical trial is to learn whether the PortionSize Ed mobile app helps to improve healthy eating habits among early adolescents in the Hawai'i-Food and Lifeskills for Youth (HI-FLY) program. PortionSize Ed is a dietary assessment and nutrition education mobile app, that provides real-time feedback on adherence to tailored dietary recommendations. HI-FLY is a healthy lifestyle program delivered in schools throughout Hawaii. PortionSize Ed also contains educational videos. Participants in this study will be randomly assigned to either the HI-FLY only group (HI-FLY), where they will receive the standard HI-FLY program or to the HI-FLY + PortionSize Ed app (HI-FLY + PSEd) group where they will receive the standard HI-FLY program and a study iPhone with the PortionSize Ed app for the 8-week study. This will allow us to evaluate the effect of the PortionSize Ed app among early adolescents in HI-FLY.

NCT ID: NCT06360354 Recruiting - Clinical trials for Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers

A Study Evaluating AMG 193 in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion

Start date: May 29, 2024
Phase: Phase 1
Study type: Interventional

The study aims to determine maximum tolerated dose (MTD) or recommended combination dose of the MTA-cooperative PRMT5 inhibitor AMG 193 administered in combination with other therapies in adult participants with metastatic or locally advanced methylthioadenosine phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety profile of AMG 193 administered in combination with other therapies in adult participants with metastatic or locally advanced MTAP-deleted gastrointestinal, biliary tract, or pancreatic cancers.